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Found 3 of ic50 for monomerid = 30452
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate BK) (HCV))
Anadys Pharmaceuticals

LigandPNGBDBM30452(Hexahydro-pyrrolo[1,2-b]pyridazin-2-one, 3 | hexah...)
Affinity DataIC50: <10nM EC50:  34nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate BK) (HCV))
Anadys Pharmaceuticals

LigandPNGBDBM30452(Hexahydro-pyrrolo[1,2-b]pyridazin-2-one, 3 | hexah...)
Affinity DataIC50: <10nM EC50:  34nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Anadys Pharmaceuticals

LigandPNGBDBM30452(Hexahydro-pyrrolo[1,2-b]pyridazin-2-one, 3 | hexah...)
Affinity DataIC50: <25nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme (NS5B H77 1a), RNA substrate, and [alpha-33P]GTP/GTP with inhibitor c...More data for this Ligand-Target Pair