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Found 5 of ic50 for monomerid = 31469
TargetCoagulation factor VII(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31469(substituted biphenyl derivative, 36i)
Affinity DataIC50:  34nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
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TargetPlasminogen(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31469(substituted biphenyl derivative, 36i)
Affinity DataIC50:  127nMT: 2°CAssay Description:The assay is an amidolytic assay based upon the absorbance of derivatized thiols from the hydrolysis of Z-Lys-SBzl (Bachem) in the presence of 5,5-Di...More data for this Ligand-Target Pair
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TargetSerine protease 1(Bos taurus (bovine))
Biocryst Pharmaceuticals

LigandPNGBDBM31469(substituted biphenyl derivative, 36i)
Affinity DataIC50:  1.66E+3nMT: 2°CAssay Description:Trypsin assay reactions were performed in a mixture containing trypsin, and test compounds were added at varied concentrations. The reactions were in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31469(substituted biphenyl derivative, 36i)
Affinity DataIC50:  5.22E+3nMT: 2°CAssay Description:FXa assay reactions were performed in a reaction mixture containing FXa, and test compounds were added at varied concentrations and reactions were in...More data for this Ligand-Target Pair
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TargetProthrombin(Homo sapiens (Human))
Biocryst Pharmaceuticals

LigandPNGBDBM31469(substituted biphenyl derivative, 36i)
Affinity DataIC50:  5.00E+4nMT: 2°CAssay Description:Thrombin assay reactions were performed in a reaction mixture containing thrombin, and test compounds were added at varied concentrations. The reacti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed