TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Guangzhou Institutes Of Biomedicine And Health
Curated by ChEMBL
Guangzhou Institutes Of Biomedicine And Health
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of Ovine COX-1 preincubated for 15 mins by fluorescence analysisMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Guangzhou Institutes Of Biomedicine And Health
Curated by ChEMBL
Guangzhou Institutes Of Biomedicine And Health
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of recombinant human COX-2 preincubated for 15 mins by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Compound was tested in vitro for inhibition of human platelet Prostaglandin G/H synthase 1 at 10 microMMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Guangzhou Institutes Of Biomedicine And Health
Curated by ChEMBL
Guangzhou Institutes Of Biomedicine And Health
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition activity against recombinant human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition activity against recombinant human Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Guangzhou Institutes Of Biomedicine And Health
Curated by ChEMBL
Guangzhou Institutes Of Biomedicine And Health
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of EGFR (unknown origin) using tyrosine 4 as substrate by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of PGHS1 assessed as conversion of arachidonic acid to prostaglandinMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibitory activity against 5-lipoxygenase catalysis (5-LO) in sonicated rat basophilic leukemia cell lysateMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Guangzhou Institutes Of Biomedicine And Health
Curated by ChEMBL
Guangzhou Institutes Of Biomedicine And Health
Curated by ChEMBL
Affinity DataIC50: 2.43E+4nMAssay Description:Compound was tested in vitro for inhibition of human umbilical cord endothelial cells(ECV-304 cell line) Prostaglandin G/H synthase 2 at 10 microMMore data for this Ligand-Target Pair