TargetHistone deacetylase 3(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human recombinant His-tagged HDAC3 expressed in baculovirus expression system incubated for 2 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human recombinant full-length His-tagged HDAC2 expressed in baculovirus expression system incubated for 2 hrs by fluorescence based ana...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human recombinant His-tagged HDAC8 expressed in Escherichia coli incubated for 2 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human recombinant His-tagged HDAC1 expressed in baculovirus expression system incubated for 2 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibitory activity against partially purified histone deacetylase of human leukemia K562 cells.More data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+5nMAssay Description:Inhibition of HDAC in human Hela cells nuclear extracts by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of LPS-induced tissue factor activity in HUVEC preincubated for 4 hrs assessed after 4 hrs of LPS challenge by one stage clotting assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+6nMAssay Description:Inhibition of TNF-alpha-induced tissue factor activity in HUVEC preincubated for 4 hrs assessed after 4 hrs of TNFalpha challenge by one stage clotti...More data for this Ligand-Target Pair