Affinity DataIC50: 20nMAssay Description:Concentration required to inhibit metabotropic glutamate receptor 2 activity of rat expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Antagonist activity at mGLUR2 expressed in CHO cells assessed as inhibition of glutamate-induced inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Taisho Pharmaceutical
Curated by ChEMBL
Taisho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Concentration required to inhibit metabotropic glutamate receptor 3 activity of rat expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Massachusetts General Hospital
Curated by ChEMBL
Massachusetts General Hospital
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Antagonist activity at mGLUR3 expressed in CHO cells assessed as inhibition of glutamate-induced inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Taisho Pharmaceutical
Curated by ChEMBL
Taisho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.74E+3nMAssay Description:Concentration required to inhibit metabotropic glutamate receptor 4 activity of rat expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 6(Rattus norvegicus (Rat))
Taisho Pharmaceutical
Curated by ChEMBL
Taisho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 2.06E+3nMAssay Description:Concentration required to inhibit metabotropic glutamate receptor 6 activity of rat expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Taisho Pharmaceutical
Curated by ChEMBL
Taisho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.17E+4nMAssay Description:Concentration required to inhibit metabotropic glutamate receptor 5 activity of rat expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9.33E+4nMAssay Description:Concentration required to inhibit metabotropic glutamate receptor 1 activity of rat expressed in CHO cellsMore data for this Ligand-Target Pair