Affinity DataIC50: 3nMAssay Description:Inhibition of rat mGluR1More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human mGluR1 expressed in 1321N1 cells assessed as effect on L-glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human mGluR1 expressed in 1321N1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Antagonist activity at mGlu1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Antagonist activity at rat mGluR1 expressed in 1321N1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 442nMAssay Description:Antagonist activity at human mGluR5 expressed in 1321N1 cells assessed as effect on L-glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: 442nMAssay Description:Antagonist activity at human mGluR5 expressed in 1321N1 cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.33E+3nMAssay Description:Antagonist activity at rat mGluR5 expressed in 1321N1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human mGluR7 expressed in 1321N1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human mGluR4 expressed in 1321N1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human mGluR2 expressed in 1321N1 cellsMore data for this Ligand-Target Pair