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Found 3 of ic50 for monomerid = 50245656
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245656(CHEMBL4059780)
Affinity DataIC50:  16nMAssay Description:Inhibition of CYP17 in Sprague-Dawley rat testes microsomes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pretreated for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245656(CHEMBL4059780)
Affinity DataIC50:  20nMAssay Description:Inhibition of recombinant human CYP17 expressed in human A549 cell membranes using 17-alpha hydroxyprogesterone as substrate and NADPH as cofactor pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50245656(CHEMBL4059780)
Affinity DataIC50:  8.56E+3nMAssay Description:Inhibition of human hepatic CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed