Compile Data Set for Download or QSAR
maximum 50k data
Found 4 of ic50 for monomerid = 50267481
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50267481(6-tert-Butyl-4-{[(4-hydroxy-5-propoxy-pyridin-2-yl...)
Affinity DataIC50:  20nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin) assessed as inhibition of retinoblastoma susceptibility gene product phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoblastoma-associated protein(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50267481(6-tert-Butyl-4-{[(4-hydroxy-5-propoxy-pyridin-2-yl...)
Affinity DataIC50:  200nMAssay Description:Inhibition of retinoblastoma susceptibility gene product phosphorylation in human MCF7 cells after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50267481(6-tert-Butyl-4-{[(4-hydroxy-5-propoxy-pyridin-2-yl...)
Affinity DataIC50:  960nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin) assessed as inhibition of retinoblastoma susceptibility gene product phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50267481(6-tert-Butyl-4-{[(4-hydroxy-5-propoxy-pyridin-2-yl...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of CDK1/Cyclin B1 (unknown origin) assessed as inhibition of retinoblastoma susceptibility gene product phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed