Affinity DataIC50: 3nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-stimulated cAMP production after 1 hr by HTRF assa...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK293 cells by scintillation counting in presence of 10% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 78nMAssay Description:Antagonist activity at EP4 receptor in human whole blood assessed as blockade of inhibition of TNFalpha-induced IP10 releaseMore data for this Ligand-Target Pair
Affinity DataIC50: 78nMAssay Description:Antagonist activity at EP4 receptor in LPS-stimulated human whole blood assessed as inhibition of PGE2-induced TNF-alpha release pretreated for 30 mi...More data for this Ligand-Target Pair