Compile Data Set for Download or QSAR
maximum 50k data
Found 4 of ic50 for monomerid = 50382686
TargetRho-associated protein kinase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50382686(CHEMBL2023154 | US9409868, 18)
Affinity DataIC50:  650nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1 [1-535](Homo sapiens (Human))
H. Lee Moffin Cancer Center and Research Institute

US Patent
LigandPNGBDBM50382686(CHEMBL2023154 | US9409868, 18)
Affinity DataIC50:  650nMpH: 7.5 T: 2°CAssay Description:A robust FRET-based, enzyme-coupled assay format, Z-Lyte® Kinase Assay Ser/Thr 13 Peptide Kit (Invitrogen, cat. PV3793), was employed in this stu...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50382686(CHEMBL2023154 | US9409868, 18)
Affinity DataIC50:  670nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2 [1-552](Homo sapiens (Human))
H. Lee Moffin Cancer Center and Research Institute

US Patent
LigandPNGBDBM50382686(CHEMBL2023154 | US9409868, 18)
Affinity DataIC50:  670nMpH: 7.5 T: 2°CAssay Description:A robust FRET-based, enzyme-coupled assay format, Z-Lyte® Kinase Assay Ser/Thr 13 Peptide Kit (Invitrogen, cat. PV3793), was employed in this stu...More data for this Ligand-Target Pair
In DepthDetails US Patent