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Found 3 of ic50 for monomerid = 50393892
TargetBeta-secretase 2(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50393892(CHEMBL2158253)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of BACE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50393892(CHEMBL2158253)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Eu-EVNLDAEFK as substrate incubated for 30 mins prior to substrate addition m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50393892(CHEMBL2158253)
Affinity DataIC50:  18nMAssay Description:Inhibition of BACE1 in human HEK cells expressing APP Swedish mutant assessed as reduction in amyloid beta40 level by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed