Found 42 of ic50 for monomerid = 50451132 TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie
Curated by ChEMBL
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:The compound was tested in vitro for high binding affinity for the Dopamine transporter (DAT) using competitive binding assay.More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie
Curated by ChEMBL
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of [3H]3-beta-(4-fluorophenyl)tropane-2beta-carboxylic acid methyl ester binding to dopamine transporter of cynomolgus monkey striatumMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie
Curated by ChEMBL
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:inhibition of [3H]WIN-35428 binding to the dopamine transporter (DAT) in monkey caudate-putamen.More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie
Curated by ChEMBL
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]WIN-35428 from monkey dopamine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:In vitro inhibitory activity against radioligand [3H]-WN 35,428 binding to dopamine transporter (DAT) in rat striatal tissueMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Concentration required to inhibit 50% of radioligand binding ([3H]WIN-35428) to the dopamine (DA) transporter in ratMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Binding affinity at the Dopamine transporter in rat striata by inhibition of 0.5 nM [3H]WIN-35428 bindingMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Compound was tested for binding affinity to dopamine reuptake sites in the tissue homogenates prepared from primate rat striatum using [3H]CFT as rad...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of [3H]WIN-35428l binding to Dopamine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Affinity against cocaine binding site of dopamine transporter in rat striatum using [3H]2b as radioligand.More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Compound was evaluated for inhibition of specifically bound [3H]- cocaine (2.7 nM) against Dopamine transporter in cynomolgus monkeysMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Displacement of 0.5 nM [3H]WIN-35248 from Dopamine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Displacement of 0.5 nM [3H]WIN-35248 from Dopamine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of dopamine Transporter Affinity against rat whole brain using [3H]WIN-35428 as radioligandMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Compound was tested for inhibitory activity to displace [3H]WIN-35428 at dopamine transporter in Rat Striatal Membranes.More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of [3H]cocaine binding to the dopamine transporter.More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of [3H]GBR-12935 binding to the dopamine transporter.More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie
Curated by ChEMBL
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie
Curated by ChEMBL
Affinity DataIC50: 139nMAssay Description:The compound was tested in vitro for low binding affinity for the Dopamine transporter (DAT) using competitive binding assay.More data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Binding affinity of [3H]citalopram for serotonin transporter in monkeyMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of [3H]citalopram binding to the serotonin transporter (5-HT) in monkey caudate-putamen.More data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Ability to inhibit [3H]citalopram binding to serotonin transporter in cynomolgus monkey striatumMore data for this Ligand-Target Pair
Affinity DataIC50: 258nMAssay Description:Inhibition of norepinephrine Transporter Affinity against rat whole brain using [3H]nisoxetine radioligandMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Biochemicals
Curated by ChEMBL
Research Biochemicals
Curated by ChEMBL
Affinity DataIC50: 479nMAssay Description:Compound was tested for binding affinity to Serotonin transporter sites in homogenates prepared from rat cortical membranes using [3H]paroxetine as r...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Biochemicals
Curated by ChEMBL
Research Biochemicals
Curated by ChEMBL
Affinity DataIC50: 690nMAssay Description:Inhibition of serotonin Transporter Affinity against rat whole brain using [3H]paroxetine as radioligandMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Biochemicals
Curated by ChEMBL
Research Biochemicals
Curated by ChEMBL
Affinity DataIC50: 692nMAssay Description:In vitro inhibitory activity against radioligand [3H]paroxetine binding to serotonin transporter (5-HTT) in rat midbrain tissueMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Biochemicals
Curated by ChEMBL
Research Biochemicals
Curated by ChEMBL
Affinity DataIC50: 692nMAssay Description:Binding affinity at the Serotonin transporter in rat midbrain by inhibition of 0.5 nM [3H]-paroxetine bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 759nMAssay Description:The compound was tested in vitro for binding affinity for the serotonin transporter (5-HTT) using competitive binding assay.More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Biochemicals
Curated by ChEMBL
Research Biochemicals
Curated by ChEMBL
Affinity DataIC50: 759nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Biochemicals
Curated by ChEMBL
Research Biochemicals
Curated by ChEMBL
Affinity DataIC50: 759nMAssay Description:Inhibition of [3H]paroxetine binding to Serotonin transporterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Biochemicals
Curated by ChEMBL
Research Biochemicals
Curated by ChEMBL
Affinity DataIC50: 810nMAssay Description:Binding potency for Serotonin transporter using [3H]- paroxetineMore data for this Ligand-Target Pair
Affinity DataIC50: 834nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie
Curated by ChEMBL
Institut F£R Bioanorganische Und Radiopharmazeutische Chemie
Curated by ChEMBL
Affinity DataIC50: 834nMAssay Description:The compound was tested in vitro for binding affinity for the norepinephrine transporter (NET) using competitive binding assay.More data for this Ligand-Target Pair
Affinity DataIC50: 835nMAssay Description:In vitro inhibitory activity against radioligand [3H]-nisoxatine binding to norepinephrine transporter (NET) in rat cortical tissueMore data for this Ligand-Target Pair
Affinity DataIC50: 835nMAssay Description:Binding potency for Norepinephrine transporter using [3H]NEMore data for this Ligand-Target Pair
Affinity DataIC50: 835nMAssay Description:Binding affinity at the Norepinephrine transporter in rat frontal cortex by inhibition of 0.5 nM [3H]nisoxetine bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of 0.5 nM [3H]nisoxetine binding toNorepinephrine transporterMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of 0.5 nM [3H]nisoxetine binding toNorepinephrine transporterMore data for this Ligand-Target Pair
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of [3H]mazindol binding to Norepinephrine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Biochemicals
Curated by ChEMBL
Research Biochemicals
Curated by ChEMBL
Affinity DataIC50: 5.06E+3nMAssay Description:Inhibition of 0.2 nM [3H]paroxetine binding to Serotonin transporterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Biochemicals
Curated by ChEMBL
Research Biochemicals
Curated by ChEMBL
Affinity DataIC50: 5.06E+3nMAssay Description:Inhibition of 0.2 nM [3H]paroxetine binding to Serotonin transporterMore data for this Ligand-Target Pair
