Found 450 of kd for monomerid = 25028 TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
University Of Basel
Curated by ChEMBL
University Of Basel
Curated by ChEMBL
Affinity DataKd: 0.760nMAssay Description:Binding affinity to human PI3Kalpha (R108 to N1068 residues) expressed in mammalian expression system by Kinomescan assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
University Of Basel
Curated by ChEMBL
University Of Basel
Curated by ChEMBL
Affinity DataKd: 0.860nMAssay Description:Binding constant for PIK3CA(E545A) kinase domainMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
University Of Basel
Curated by ChEMBL
University Of Basel
Curated by ChEMBL
Affinity DataKd: 1.10nMAssay Description:Binding constant for PIK3CA kinase domainMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
University Of Basel
Curated by ChEMBL
University Of Basel
Curated by ChEMBL
Affinity DataKd: 1.20nMAssay Description:Binding constant for PIK3CA(E545K) kinase domainMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
University Of Basel
Curated by ChEMBL
University Of Basel
Curated by ChEMBL
Affinity DataKd: 1.5nMAssay Description:Binding constant for PIK3CA(C420R) kinase domainMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
University Of Basel
Curated by ChEMBL
University Of Basel
Curated by ChEMBL
Affinity DataKd: 1.5nMAssay Description:Binding constant for PIK3CA(E542K) kinase domainMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
University Of Basel
Curated by ChEMBL
University Of Basel
Curated by ChEMBL
Affinity DataKd: 1.70nMAssay Description:Binding constant for PIK3CA(Q546K) kinase domainMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
University Of Basel
Curated by ChEMBL
University Of Basel
Curated by ChEMBL
Affinity DataKd: 2.10nMAssay Description:Binding affinity to human PI3Kbeta (P118 to S1070 residues) expressed in mammalian expression system by Kinomescan assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
University Of Basel
Curated by ChEMBL
University Of Basel
Curated by ChEMBL
Affinity DataKd: 3.30nMAssay Description:Binding affinity to human PI3Kdelta (R108 to Q1044 residues) expressed in mammalian expression system by Kinomescan assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
University Of Basel
Curated by ChEMBL
University Of Basel
Curated by ChEMBL
Affinity DataKd: 3.70nMAssay Description:Binding constant for PIK3CA(H1047L) kinase domainMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
University Of Basel
Curated by ChEMBL
University Of Basel
Curated by ChEMBL
Affinity DataKd: 4.10nMAssay Description:Binding constant for PIK3CA(H1047Y) kinase domainMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
University Of Basel
Curated by ChEMBL
University Of Basel
Curated by ChEMBL
Affinity DataKd: 4.5nMAssay Description:Binding constant for PIK3CA(M1043I) kinase domainMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
University Of Basel
Curated by ChEMBL
University Of Basel
Curated by ChEMBL
Affinity DataKd: 5nMAssay Description:Binding constant for PIK3CD kinase domainMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
University Of Basel
Curated by ChEMBL
University Of Basel
Curated by ChEMBL
Affinity DataKd: 7.10nMAssay Description:Binding constant for PIK3CA(I800L) kinase domainMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
University Of Basel
Curated by ChEMBL
University Of Basel
Curated by ChEMBL
Affinity DataKd: 7.70nMAssay Description:In vitro renin inhibition was measured at pH 7.4 by using human plasma renin assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
University Of Basel
Curated by ChEMBL
University Of Basel
Curated by ChEMBL
Affinity DataKd: 16nMAssay Description:Binding constant for PIK3CB kinase domainMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
University Of Basel
Curated by ChEMBL
University Of Basel
Curated by ChEMBL
Affinity DataKd: 40nMAssay Description:Binding affinity to human PI3KC2beta (M1 to L1634 residues) expressed in mammalian expression system by Kinomescan assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
University Of Basel
Curated by ChEMBL
University Of Basel
Curated by ChEMBL
Affinity DataKd: 48nMAssay Description:Binding constant for PIK3CG kinase domainMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
University Of Basel
Curated by ChEMBL
University Of Basel
Curated by ChEMBL
Affinity DataKd: 48nMAssay Description:Binding affinity to human mTOR (L1382 to W2549 residues) expressed in mammalian expression system at 10 uMMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
University Of Basel
Curated by ChEMBL
University Of Basel
Curated by ChEMBL
Affinity DataKd: 130nMAssay Description:Binding constant for PIK3C2B kinase domainMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
University Of Basel
Curated by ChEMBL
University Of Basel
Curated by ChEMBL
Affinity DataKd: 200nMAssay Description:Binding constant for MTOR kinase domainMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase C2 domain-containing subunit gamma(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 300nMAssay Description:Binding constant for PIK3C2G kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 430nMAssay Description:Binding constant for JAK1(JH2domain-pseudokinase) kinase domainMore data for this Ligand-Target Pair
TargetHomeodomain-interacting protein kinase 2(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 520nMAssay Description:Binding constant for HIPK2 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 560nMAssay Description:Binding constant for JNK3 kinase domainMore data for this Ligand-Target Pair
TargetHomeodomain-interacting protein kinase 3(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 600nMAssay Description:Binding constant for HIPK3 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 600nMAssay Description:Binding constant for CLK2 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 670nMAssay Description:Binding constant for RIOK2 kinase domainMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 710nMAssay Description:Binding constant for FLT3(D835Y) kinase domainMore data for this Ligand-Target Pair
TargetMyosin light chain kinase family member 4(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 780nMAssay Description:Binding constant for MYLK4 kinase domainMore data for this Ligand-Target Pair
TargetHomeodomain-interacting protein kinase 1(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 1.10E+3nMAssay Description:Binding constant for HIPK1 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.10E+3nMAssay Description:Binding constant for PCTK1 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.10E+3nMAssay Description:Binding constant for CLK1 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.10E+3nMAssay Description:Binding constant for STK16 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.20E+3nMAssay Description:Binding constant for CSNK1E kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.20E+3nMAssay Description:Binding constant for CSNK1D kinase domainMore data for this Ligand-Target Pair
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
University Of Basel
Curated by ChEMBL
University Of Basel
Curated by ChEMBL
Affinity DataKd: 1.30E+3nMAssay Description:In vitro renin inhibition was measured at pH 7.4 by using purified human kidney renin assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.50E+3nMAssay Description:Binding constant for JNK1 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.50E+3nMAssay Description:Binding constant for CLK4 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.60E+3nMAssay Description:Binding constant for EPHB6 kinase domainMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 1.70E+3nMAssay Description:Binding constant for FLT3(D835H) kinase domainMore data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 3(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 1.70E+3nMAssay Description:Binding constant for IRAK3 kinase domainMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 1.80E+3nMAssay Description:Binding constant for TYK2(JH2domain-pseudokinase) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.80E+3nMAssay Description:Binding constant for JNK2 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.80E+3nMAssay Description:Binding constant for DAPK3 kinase domainMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 2.20E+3nMAssay Description:Binding constant for FLT3(ITD) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 2.40E+3nMAssay Description:Binding constant for CSNK2A2 kinase domainMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 2.60E+3nMAssay Description:Binding constant for FLT3(K663Q) kinase domainMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Ambit Biosciences
Curated by ChEMBL
Ambit Biosciences
Curated by ChEMBL
Affinity DataKd: 2.60E+3nMAssay Description:Binding constant for FLT3 kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 2.60E+3nMAssay Description:Binding constant for PLK4 kinase domainMore data for this Ligand-Target Pair
