TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
University Of Basel
Curated by ChEMBL
University Of Basel
Curated by ChEMBL
Affinity DataKd: 0.140nMAssay Description:Inhibition of human mTOR (1382 to 2549 residues) expressed in mammalian expression system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
University Of Basel
Curated by ChEMBL
University Of Basel
Curated by ChEMBL
Affinity DataKd: 33nMAssay Description:Inhibition of human PI3Kalpha (108 to 1068 residues) expressed in mammalian expression system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
University Of Basel
Curated by ChEMBL
University Of Basel
Curated by ChEMBL
Affinity DataKd: 1.50E+3nMAssay Description:Inhibition of human PI3Kdelta (108 to 1044 residues) expressed in mammalian expression system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
University Of Basel
Curated by ChEMBL
University Of Basel
Curated by ChEMBL
Affinity DataKd: 3.30E+3nMAssay Description:Inhibition of human PI3Kbeta (118 to 1070 residues) expressed in mammalian expression system by KINOMEscan assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.40E+3nMAssay Description:Briefly, 5 mg of a protein mixture of the four cell lines or a single cell line were incubated with compound dilution series in DMSO (3 nM, 10 nM, 30...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
University Of Basel
Curated by ChEMBL
University Of Basel
Curated by ChEMBL
Affinity DataKd: 8.40E+3nMAssay Description:Inhibition of human PI3Kgamma (144 to 1102 residues) expressed in mammalian expression system by KINOMEscan assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
University Of Basel
Curated by ChEMBL
University Of Basel
Curated by ChEMBL
Affinity DataKd: 2.30E+4nMAssay Description:Inhibition of human VPS34 (282 to 879 residues) expressed in mammalian expression system by KINOMEscan assayMore data for this Ligand-Target Pair
Affinity DataKd: >3.00E+4nMAssay Description:Inhibition of human PI4Kbeta (1 to 828 residues) expressed in mammalian expression system by KINOMEscan assayMore data for this Ligand-Target Pair