Compile Data Set for Download or QSAR
maximum 50k data
Found 18 of ki for monomerid = 50258424
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50258424(CHEMBL494221 | trans-4-(3-(3-(trifluoromethyl)phen...)
Affinity DataKi:  230nMAssay Description:Inhibition of GSK3beta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50258424(CHEMBL494221 | trans-4-(3-(3-(trifluoromethyl)phen...)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of PKCtheta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50258424(CHEMBL494221 | trans-4-(3-(3-(trifluoromethyl)phen...)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50258424(CHEMBL494221 | trans-4-(3-(3-(trifluoromethyl)phen...)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50258424(CHEMBL494221 | trans-4-(3-(3-(trifluoromethyl)phen...)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50258424(CHEMBL494221 | trans-4-(3-(3-(trifluoromethyl)phen...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50258424(CHEMBL494221 | trans-4-(3-(3-(trifluoromethyl)phen...)
Affinity DataKi:  3.10E+3nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50258424(CHEMBL494221 | trans-4-(3-(3-(trifluoromethyl)phen...)
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of ITK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50258424(CHEMBL494221 | trans-4-(3-(3-(trifluoromethyl)phen...)
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50258424(CHEMBL494221 | trans-4-(3-(3-(trifluoromethyl)phen...)
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of COT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50258424(CHEMBL494221 | trans-4-(3-(3-(trifluoromethyl)phen...)
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50258424(CHEMBL494221 | trans-4-(3-(3-(trifluoromethyl)phen...)
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50258424(CHEMBL494221 | trans-4-(3-(3-(trifluoromethyl)phen...)
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of MAP3K7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50258424(CHEMBL494221 | trans-4-(3-(3-(trifluoromethyl)phen...)
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of MET (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50258424(CHEMBL494221 | trans-4-(3-(3-(trifluoromethyl)phen...)
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50258424(CHEMBL494221 | trans-4-(3-(3-(trifluoromethyl)phen...)
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50258424(CHEMBL494221 | trans-4-(3-(3-(trifluoromethyl)phen...)
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50258424(CHEMBL494221 | trans-4-(3-(3-(trifluoromethyl)phen...)
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of SRC (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed