Compile Data Set for Download or QSAR
maximum 50k data
Found 11 of ki for monomerid = 50341680
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Northwestern University

US Patent
LigandPNGBDBM50341680(6,6'-(2,2'-(Pyridine-2,6-diyl)bis(ethane-2,1-diyl)...)
Affinity DataKi:  99nMAssay Description:The NOSs isoform assays involved subjecting 3-8 to an oxyhemoglobin NO capture assay using a Biotek Gen5™ microplate reader. IC50 values for each com...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

US Patent
LigandPNGBDBM50341680(6,6'-(2,2'-(Pyridine-2,6-diyl)bis(ethane-2,1-diyl)...)
Affinity DataKi:  99nMAssay Description:Enzyme inhibition was evaluated by measuring NO production with the hemoglobin capture assay, which was performed with purified NOSs in 96-well plate...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

US Patent
LigandPNGBDBM50341680(6,6'-(2,2'-(Pyridine-2,6-diyl)bis(ethane-2,1-diyl)...)
Affinity DataKi:  99nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli by UV-vis spectrometric analysisMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

US Patent
LigandPNGBDBM50341680(6,6'-(2,2'-(Pyridine-2,6-diyl)bis(ethane-2,1-diyl)...)
Affinity DataKi:  4.75E+3nMAssay Description:Enzyme inhibition was evaluated by measuring NO production with the hemoglobin capture assay, which was performed with purified NOSs in 96-well plate...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Northwestern University

US Patent
LigandPNGBDBM50341680(6,6'-(2,2'-(Pyridine-2,6-diyl)bis(ethane-2,1-diyl)...)
Affinity DataKi:  4.75E+3nMAssay Description:The NOSs isoform assays involved subjecting 3-8 to an oxyhemoglobin NO capture assay using a Biotek Gen5™ microplate reader. IC50 values for each com...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

US Patent
LigandPNGBDBM50341680(6,6'-(2,2'-(Pyridine-2,6-diyl)bis(ethane-2,1-diyl)...)
Affinity DataKi:  4.75E+3nMAssay Description:Inhibition of mouse macrophage recombinant iNOS expressed in Escherichia coli by UV-vis spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Northwestern University

US Patent
LigandPNGBDBM50341680(6,6'-(2,2'-(Pyridine-2,6-diyl)bis(ethane-2,1-diyl)...)
Affinity DataKi:  4.75E+3nMAssay Description:Inhibition assay using nitric oxide synthases.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50341680(6,6'-(2,2'-(Pyridine-2,6-diyl)bis(ethane-2,1-diyl)...)
Affinity DataKi:  9.40E+3nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli by UV-vis spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50341680(6,6'-(2,2'-(Pyridine-2,6-diyl)bis(ethane-2,1-diyl)...)
Affinity DataKi:  9.40E+3nMAssay Description:Enzyme inhibition was evaluated by measuring NO production with the hemoglobin capture assay, which was performed with purified NOSs in 96-well plate...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Northwestern University

US Patent
LigandPNGBDBM50341680(6,6'-(2,2'-(Pyridine-2,6-diyl)bis(ethane-2,1-diyl)...)
Affinity DataKi:  9.40E+3nMAssay Description:The NOSs isoform assays involved subjecting 3-8 to an oxyhemoglobin NO capture assay using a Biotek Gen5™ microplate reader. IC50 values for each com...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Northwestern University

US Patent
LigandPNGBDBM50341680(6,6'-(2,2'-(Pyridine-2,6-diyl)bis(ethane-2,1-diyl)...)
Affinity DataKi:  9.40E+3nMAssay Description:Inhibition assay using nitric oxide synthases.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed