Compile Data Set for Download or QSAR
Report error Found 1 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3 [781-1124]' and Ligand = 'BDBM493018'
TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 493018BDBM493018(US10981906, Example 117 | ethyl (R)-4-((1-(2-cyano...)
Affinity DataIC50: 550nMAssay Description:The activity of JAK3 (a.a. 781-1124, ThermoFisher) was quantified by measuring the phosphorylation of SRCtide (FAM-GEEPLYWSFPAKKK-NH2). Kinase reacti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2021
Entry Details
US Patent