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TargetD(2) dopamine receptor(Homo sapiens (Human))TBA
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)
Affinity DataKi:  0.5nM ΔG°:  -54.0kJ/mole IC50:  2.56nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
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TargetD(2) dopamine receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50429044(CHEMBL2334893 | US9359372, DC037029)
Affinity DataKi:  32.2nM ΔG°:  -43.5kJ/mole IC50:  91.1nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50387557(CHEMBL2057457 | US9359372, DC037031)
Affinity DataKi:  161nM ΔG°:  -39.4kJ/mole IC50:  456nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50387560(CHEMBL2057451 | US9359372, DC037017)
Affinity DataKi:  224nM ΔG°:  -38.6kJ/mole IC50:  1.16E+3nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))TBA
LigandPNGBDBM235775(US9359372, DC037012)
Affinity DataKi:  240nM ΔG°:  -38.4kJ/mole IC50:  1.24E+3nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetD(2) dopamine receptor(Homo sapiens (Human))TBA
LigandPNGBDBM235773(US9359372, DC037008)
Affinity DataKi:  334nM ΔG°:  -37.6kJ/mole IC50:  1.73E+3nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetD(2) dopamine receptor(Homo sapiens (Human))TBA
LigandPNGBDBM235777(US9359372, DC037013 | US9359372, DC037034)
Affinity DataKi:  485nM ΔG°:  -36.6kJ/mole IC50:  2.51E+3nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent