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Found 1037 from Bioprojet-Biotech
TargetCoagulation factor X(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652658(4-N-[[2-[(1-methyl-4-piperidyl)methoxy]-4-pyridyl]...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652658(4-N-[[2-[(1-methyl-4-piperidyl)methoxy]-4-pyridyl]...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652659(N8-((2-((1-methylpiperidin-4-yl)methoxy)pyridin-4-...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652659(N8-((2-((1-methylpiperidin-4-yl)methoxy)pyridin-4-...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652660(1-(5-{[(4-{[(1-aminoisoquinolin-5-yl)amino]methyl}...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652662(5-N-{[2-({2-methyl-2-azabicyclo[2.2.1]heptan-5-yl}...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652662(5-N-{[2-({2-methyl-2-azabicyclo[2.2.1]heptan-5-yl}...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652664(5-N-[[2-[(3-methyl-3-azabicyclo[3.2.1]octan-8-yl)m...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652664(5-N-[[2-[(3-methyl-3-azabicyclo[3.2.1]octan-8-yl)m...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652665((5S)-5-{[(4-{[(1-aminoisoquinolin-5-yl)amino]methy...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652665((5S)-5-{[(4-{[(1-aminoisoquinolin-5-yl)amino]methy...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652665((5S)-5-{[(4-{[(1-aminoisoquinolin-5-yl)amino]methy...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652666((5R)-5-{[(4-{[(1-aminoisoquinolin-5-yl)amino]methy...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652666((5R)-5-{[(4-{[(1-aminoisoquinolin-5-yl)amino]methy...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652666((5R)-5-{[(4-{[(1-aminoisoquinolin-5-yl)amino]methy...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652667(5-N-[[2-[(1-methyl-4-piperidyl)methoxy]-6-(trifluo...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652667(5-N-[[2-[(1-methyl-4-piperidyl)methoxy]-6-(trifluo...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652667(5-N-[[2-[(1-methyl-4-piperidyl)methoxy]-6-(trifluo...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652668(5-N-({2-[2-(1-methylimidazol-2-yl)ethoxy]pyridin-4...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652668(5-N-({2-[2-(1-methylimidazol-2-yl)ethoxy]pyridin-4...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652671(4-chloro-6-N-[(2-{[(1-methylpiperidin-4-yl)methyl]...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652671(4-chloro-6-N-[(2-{[(1-methylpiperidin-4-yl)methyl]...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652672(N5-((2-(((1-methylpiperidin-4-yl)methyl)amino)pyri...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652672(N5-((2-(((1-methylpiperidin-4-yl)methyl)amino)pyri...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652675(4-(((1-aminoisoquinolin-5-yl)amino)methyl)-N-(1-me...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652675(4-(((1-aminoisoquinolin-5-yl)amino)methyl)-N-(1-me...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652675(4-(((1-aminoisoquinolin-5-yl)amino)methyl)-N-(1-me...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652676(3-N-({2-[(1-methylpiperidin-4-yl)methoxy]pyridin-4...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652677(5-N-[(2-{[(1R,4R)-5-isopropyl-2,5-diazabicyclo[2.2...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652677(5-N-[(2-{[(1R,4R)-5-isopropyl-2,5-diazabicyclo[2.2...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652677(5-N-[(2-{[(1R,4R)-5-isopropyl-2,5-diazabicyclo[2.2...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652677(5-N-[(2-{[(1R,4R)-5-isopropyl-2,5-diazabicyclo[2.2...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652604(4-chloro-6-N-({2-fluoro-4-[2-(4-methylpiperazin-1-...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652604(4-chloro-6-N-({2-fluoro-4-[2-(4-methylpiperazin-1-...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652605(6-N-[(4-{[(1-methylpiperidin-4-yl)oxy]methyl}pheny...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652606(5-N-[(4-{[(1-methylpiperidin-4-yl)oxy]methyl}pheny...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652606(5-N-[(4-{[(1-methylpiperidin-4-yl)oxy]methyl}pheny...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652611(6-N-[(2-fluoro-4-{[(1-methylpiperidin-4-yl)oxy]met...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652611(6-N-[(2-fluoro-4-{[(1-methylpiperidin-4-yl)oxy]met...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652612(6-N-[(2-chloro-4-{[(1-methylpiperidin-4-yl)oxy]met...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652614(6-N-[(4-{[(3,3-difluoro-1-methylpiperidin-4-yl)oxy...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652615(6-N-[(4-{[(1-cyclopropylpiperidin-4-yl)oxy]methyl}...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652616(6-N-{[4-({[1-(2,2-difluoroethyl)piperidin-4-yl]oxy...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652626(5-N-[[2-fluoro-4-[(2-methyl-2-azaspiro[3.3]heptan-...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652626(5-N-[[2-fluoro-4-[(2-methyl-2-azaspiro[3.3]heptan-...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652628(5-N-[[2-fluoro-4-[2-(1-methylimidazol-2-yl)ethoxym...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652629(5-[[4-[[(1-amino-5-isoquinolyl)amino]methyl]-3-flu...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652629(5-[[4-[[(1-amino-5-isoquinolyl)amino]methyl]-3-flu...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652629(5-[[4-[[(1-amino-5-isoquinolyl)amino]methyl]-3-flu...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM652631(N-(4-(((1-aminoisoquinolin-5-yl)amino)methyl)-3-fl...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of related proteases was determined using an (C50 assay based on standard literature methods (see e.g. Shori et al., Biochem. Pha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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