Compile Data Set for Download or QSAR
maximum 50k data
Found 10 of ic50 for monomerid = 104500
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM104500(US8575114, I-12)
Affinity DataIC50:  33nMAssay Description:Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of [14C]-AMG uptake after 3 hrs by microbeta scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM104500(US8575114, I-12)
Affinity DataIC50:  36.6nMAssay Description:The inhibitory activity of the compounds of this invention against the SGLT-1 or SGLT-2 transporters.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 1A2(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM104500(US8575114, I-12)
Affinity DataIC50: >1.10E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM104500(US8575114, I-12)
Affinity DataIC50: >1.10E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM104500(US8575114, I-12)
Affinity DataIC50: >1.10E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM104500(US8575114, I-12)
Affinity DataIC50: >1.10E+4nMAssay Description:Inhibition of CYP2B6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM104500(US8575114, I-12)
Affinity DataIC50: >1.10E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM104500(US8575114, I-12)
Affinity DataIC50: >1.10E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM104500(US8575114, I-12)
Affinity DataIC50: >9.00E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHOK1 cells assessed as inhibition of [14C]-AMG uptake after 3 hrs by microbeta scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Amri

Curated by ChEMBL
LigandPNGBDBM104500(US8575114, I-12)
Affinity DataIC50: >9.00E+4nMAssay Description:The inhibitory activity of the compounds of this invention against the SGLT-1 or SGLT-2 transporters.More data for this Ligand-Target Pair
In DepthDetails US Patent