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Found 14 of ic50 for monomerid = 238345
TargetRAF proto-oncogene serine/threonine-protein kinase [Y340D,Y341D](Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM238345(US9388165, 1)
Affinity DataIC50:  6.10nMAssay Description:The compounds prepared in Examples were tested for inhibitory activities against three subtypes of RAF, i.e. RAF1 Y340D Y341D, BRAF normal type and B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM238345(US9388165, 1)
Affinity DataIC50:  61nMAssay Description:In a similar manner to Experimental Example 1, the % inhibitory activity (concentration of the compound 1.0 μM) and the IC50 values of the inven...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM238345(US9388165, 1)
Affinity DataIC50:  66nMAssay Description:In a similar manner to Experimental Example 1, the % inhibitory activity (concentration of the compound 1.0 μM) and the IC50 values of the inven...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM238345(US9388165, 1)
Affinity DataIC50:  87nMAssay Description:In a similar manner to Experimental Example 1, the % inhibitory activity (concentration of the compound 1.0 μM) and the IC50 values of the inven...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM238345(US9388165, 1)
Affinity DataIC50:  261nMAssay Description:In a similar manner to Experimental Example 1, the % inhibitory activity (concentration of the compound 1.0 μM) and the IC50 values of the inven...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM238345(US9388165, 1)
Affinity DataIC50:  393nMAssay Description:In a similar manner to Experimental Example 1, the % inhibitory activity (concentration of the compound 1.0 μM) and the IC50 values of the inven...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM238345(US9388165, 1)
Affinity DataIC50: >2.50E+3nMAssay Description:In a similar manner to Experimental Example 1, the % inhibitory activity (concentration of the compound 1.0 μM) and the IC50 values of the inven...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM238345(US9388165, 1)
Affinity DataIC50: >2.50E+3nMAssay Description:In a similar manner to Experimental Example 1, the % inhibitory activity (concentration of the compound 1.0 μM) and the IC50 values of the inven...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM238345(US9388165, 1)
Affinity DataIC50: >2.50E+3nMAssay Description:In a similar manner to Experimental Example 1, the % inhibitory activity (concentration of the compound 1.0 μM) and the IC50 values of the inven...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM238345(US9388165, 1)
Affinity DataIC50: >2.50E+3nMAssay Description:In a similar manner to Experimental Example 1, the % inhibitory activity (concentration of the compound 1.0 μM) and the IC50 values of the inven...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM238345(US9388165, 1)
Affinity DataIC50: >2.50E+3nMAssay Description:In a similar manner to Experimental Example 1, the % inhibitory activity (concentration of the compound 1.0 μM) and the IC50 values of the inven...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM238345(US9388165, 1)
Affinity DataIC50: >2.50E+3nMAssay Description:In a similar manner to Experimental Example 1, the % inhibitory activity (concentration of the compound 1.0 μM) and the IC50 values of the inven...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM238345(US9388165, 1)
Affinity DataIC50: >2.50E+3nMAssay Description:In a similar manner to Experimental Example 1, the % inhibitory activity (concentration of the compound 1.0 μM) and the IC50 values of the inven...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM238345(US9388165, 1)
Affinity DataIC50: >2.50E+3nMAssay Description:In a similar manner to Experimental Example 1, the % inhibitory activity (concentration of the compound 1.0 μM) and the IC50 values of the inven...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent