TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Displacement of (R)-Na-Diphenylacetyl-Nomega[2-([2,3-3H]-propionylamino)ethyl]aminocarbonyl (4-hydroxybenzyl)-argininamide from NPY1R in human SK-N-M...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataIC50: 8.80nMAssay Description:Inhibition of neuropeptide Y1 receptor in human SK-N-MC cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 10 mins by Fura-2 dye bas...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 10 secs by Fura-2 dye bas...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 5 mins by Fura-2 dye base...More data for this Ligand-Target Pair