Compile Data Set for Download or QSAR
maximum 50k data
Found 16 of ic50 for monomerid = 50156055
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Cephalon (France)

Curated by ChEMBL
LigandPNGBDBM50156055(2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of rat DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Cephalon (France)

Curated by ChEMBL
LigandPNGBDBM50156055(2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...)
Affinity DataIC50:  3.70E+3nMAssay Description:Displacement of 3H-WIN-35428 from DAT in rat striata after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Cephalon (France)

Curated by ChEMBL
LigandPNGBDBM50156055(2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of rat DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Cephalon (France)

Curated by ChEMBL
LigandPNGBDBM50156055(2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...)
Affinity DataIC50: >3.80E+3nMAssay Description:Inhibition of rat brain DAT assessed as reduction of [3H]-DA re-uptake preincubated for 30 mins followed by [3H]-DA addition measured after 5 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Cephalon (France)

Curated by ChEMBL
LigandPNGBDBM50156055(2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of rat DAT-mediated dopamine reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Cephalon (France)

Curated by ChEMBL
LigandPNGBDBM50156055(2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of rat DAT-mediated dopamine reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Biocon Bristol-Myers Squibb R&D Centre

Curated by ChEMBL
LigandPNGBDBM50156055(2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat brain NET assessed as reduction of [3H]-NE re-uptake preincubated for 30 mins followed by [3H]-NE addition measured after 5 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Cephalon (France)

Curated by ChEMBL
LigandPNGBDBM50156055(2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCytochrome P450 2C19(Homo sapiens (Human))
Cephalon (France)

Curated by ChEMBL
LigandPNGBDBM50156055(2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCytochrome P450 2C19(Homo sapiens (Human))
Cephalon (France)

Curated by ChEMBL
LigandPNGBDBM50156055(2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
University of Vienna

Curated by ChEMBL
LigandPNGBDBM50156055(2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...)
Affinity DataIC50:  1.15E+4nMAssay Description:Inhibition of re-uptake of [3H]-dopamine at human DAT expressed in HEK293 cells preincubated for 5 mins followed by [3H]-dopamine addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetTransporter(Rattus norvegicus (rat))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50156055(2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...)
Affinity DataIC50:  6.39E+4nMAssay Description:Inhibition of rat NET-mediated norepinephrine reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50156055(2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...)
Affinity DataIC50:  6.39E+4nMAssay Description:Inhibition of rat NET-mediated norepinephrine reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Vienna

Curated by ChEMBL
LigandPNGBDBM50156055(2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...)
Affinity DataIC50:  2.84E+5nMAssay Description:Inhibition of re-uptake of [3H]MPP+ at human NET expressed in HEK293 cells preincubated for 5 mins followed by [3H]-dopamine addition measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50156055(2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of rat SERT-mediated serotonin reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50156055(2-(Diphenyl-methanesulfinyl)-acetamide | 2-(benzhy...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of rat SERT-mediated serotonin reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed