TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Cephalon (France)
Curated by ChEMBL
Cephalon (France)
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of rat DATMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Cephalon (France)
Curated by ChEMBL
Cephalon (France)
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Displacement of 3H-WIN-35428 from DAT in rat striata after 120 minsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Cephalon (France)
Curated by ChEMBL
Cephalon (France)
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of rat DATMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Cephalon (France)
Curated by ChEMBL
Cephalon (France)
Curated by ChEMBL
Affinity DataIC50: >3.80E+3nMAssay Description:Inhibition of rat brain DAT assessed as reduction of [3H]-DA re-uptake preincubated for 30 mins followed by [3H]-DA addition measured after 5 mins by...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Cephalon (France)
Curated by ChEMBL
Cephalon (France)
Curated by ChEMBL
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of rat DAT-mediated dopamine reuptakeMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Cephalon (France)
Curated by ChEMBL
Cephalon (France)
Curated by ChEMBL
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of rat DAT-mediated dopamine reuptakeMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat brain NET assessed as reduction of [3H]-NE re-uptake preincubated for 30 mins followed by [3H]-NE addition measured after 5 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
University of Vienna
Curated by ChEMBL
University of Vienna
Curated by ChEMBL
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of re-uptake of [3H]-dopamine at human DAT expressed in HEK293 cells preincubated for 5 mins followed by [3H]-dopamine addition measured a...More data for this Ligand-Target Pair
Affinity DataIC50: 6.39E+4nMAssay Description:Inhibition of rat NET-mediated norepinephrine reuptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 6.39E+4nMAssay Description:Inhibition of rat NET-mediated norepinephrine reuptakeMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University of Vienna
Curated by ChEMBL
University of Vienna
Curated by ChEMBL
Affinity DataIC50: 2.84E+5nMAssay Description:Inhibition of re-uptake of [3H]MPP+ at human NET expressed in HEK293 cells preincubated for 5 mins followed by [3H]-dopamine addition measured after ...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of rat SERT-mediated serotonin reuptakeMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of rat SERT-mediated serotonin reuptakeMore data for this Ligand-Target Pair