BindingDB PrimarySearch

Found 19 of ec50 for monomerid = 50239940

RNA-directed RNA polymerase(Hepatitis C virus)
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)

EC50: 64nMAssay Description:Inhibition of Hepatitis C virus genotype 1b NS5B RNA-dependent-RNA polymerase assessed as reduction in viral replication after 72 hrs by indirect imm...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/TrEMBL
B.MOAD GoogleScholar

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RNA-directed RNA polymerase(Hepatitis C virus)
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)

EC50: 230nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1b Con1 infected in human HuH7 replicon cells assessed as inhibition of viral replication after 3 days ...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/TrEMBL
B.MOAD GoogleScholar

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Genome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL

BDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)

EC50: 120nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus infected in human NPC assessed as antiviral activity by DAPI-staining based assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar

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RNA-directed RNA polymerase(Hepatitis C virus)
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)

EC50: 44nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1b/5a chimeric replicon infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/TrEMBL
B.MOAD GoogleScholar

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RNA-directed RNA polymerase(Hepatitis C virus)
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)

EC50: 300nMAssay Description:Inhibition of NS5B polymerase S282T mutant in HCV genotype 1b infected in human Huh7 replicon cells after 5 days by RT-PCR assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/TrEMBL
B.MOAD GoogleScholar

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RNA-directed RNA polymerase(Hepatitis C virus)
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)

EC50: 58nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1b/4a chimeric replicon infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/TrEMBL
B.MOAD GoogleScholar

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Details Article PubMed

RNA-directed RNA polymerase(Hepatitis C virus)
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)

PDB Reactome pathway
UniProtKB/TrEMBL
B.MOAD GoogleScholar

Purchase MCE
PC cid PC sid PDB Similars

Details Article PubMed

RNA-directed RNA polymerase(Hepatitis C virus)
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)

EC50: 61nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1a infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/TrEMBL
B.MOAD GoogleScholar

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Details Article PubMed

RNA-directed RNA polymerase(Hepatitis C virus)
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)

EC50: 34nMAssay Description:Inhibition of NS5B polymerase in wild type HCV genotype 1b infected in human Huh7 replicon cells after 5 days by RT-PCR assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/TrEMBL
B.MOAD GoogleScholar

Purchase MCE
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Details Article PubMed

RNA-directed RNA polymerase(Hepatitis C virus)
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)

EC50: 43nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 2a infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/TrEMBL
B.MOAD GoogleScholar

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Details Article PubMed

RNA-directed RNA polymerase(Hepatitis C virus)
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)

EC50: 43nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 2a infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/TrEMBL
B.MOAD GoogleScholar

Purchase MCE
PC cid PC sid PDB Similars

Details Article PubMed

RNA-directed RNA polymerase(Hepatitis C virus)
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)

PDB Reactome pathway
UniProtKB/TrEMBL
B.MOAD GoogleScholar

Purchase MCE
PC cid PC sid PDB Similars

Details Article PubMed

RNA-directed RNA polymerase(Hepatitis C virus)
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)

EC50: 300nMAssay Description:Inhibition of NS5B polymerase S282T mutant in HCV genotype 1b infected in human Huh7 replicon cells after 5 days by RT-PCR assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/TrEMBL
B.MOAD GoogleScholar

Purchase MCE
PC cid PC sid PDB Similars

Details Article PubMed

RNA-directed RNA polymerase(Hepatitis C virus)
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)

EC50: 61nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1a infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/TrEMBL
B.MOAD GoogleScholar

Purchase MCE
PC cid PC sid PDB Similars

Details Article PubMed

RNA-directed RNA polymerase(Hepatitis C virus)
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)

EC50: 34nMAssay Description:Inhibition of NS5B polymerase in wild type HCV genotype 1b infected in human Huh7 replicon cells after 5 days by RT-PCR assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/TrEMBL
B.MOAD GoogleScholar

Purchase MCE
PC cid PC sid PDB Similars

Details Article PubMed

RNA-directed RNA polymerase(Hepatitis C virus)
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)

EC50: 64nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1b/3a chimeric replicon infected in human HuH7 replicon cells after 5 days by RT-PCR analysisMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/TrEMBL
B.MOAD GoogleScholar

Purchase MCE
PC cid PC sid PDB Similars

Details Article PubMed

RNA-directed RNA polymerase(Hepatitis C virus)
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)

PDB Reactome pathway
UniProtKB/TrEMBL
B.MOAD GoogleScholar

Purchase MCE
PC cid PC sid PDB Similars

Details Article PubMed

RNA-directed RNA polymerase(Hepatitis C virus)
Shenyang Pharmaceutical University

Curated by ChEMBL

BDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)

EC50: 155nMAssay Description:Inhibition of NS5B polymerase in HCV genotype 1a H77 infected in human HuH7 replicon cells assessed as inhibition of viral replication after 3 days b...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/TrEMBL
B.MOAD GoogleScholar

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Details Article PubMed

Genome polyprotein(Zika virus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL

BDBM50239940(CHEBI:85083 | PSI-7977, GS-7977 | Sofosbuvir | Sov...)

EC50: 3.09E+4nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus infected in African green monkey Vero cells assessed as antiviral activity by DAPI-staining ...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar

Purchase MCE
PC cid PC sid PDB Similars

Details Article PubMed