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Found 17 of ic50 for monomerid = 50342601
TargetAcetylcholinesterase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50342601(CHEMBL1255901 | Huperzine A)
Affinity DataIC50:  0.540nMAssay Description:Inhibition of acetylcholinesterase (unknown origin) assessed as inhibition of acetylcholine hydrolysis after 30 mins by Ellmann's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50342601(CHEMBL1255901 | Huperzine A)
Affinity DataIC50:  5nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50342601(CHEMBL1255901 | Huperzine A)
Affinity DataIC50:  5nMAssay Description:In vitro inhibitory activity against Acetylcholinesterase (AChE).More data for this Ligand-Target Pair
In DepthDetails Article
TargetAcetylcholinesterase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50342601(CHEMBL1255901 | Huperzine A)
Affinity DataIC50:  5nMAssay Description:Inhibition of AChE-induced amyloid beta aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50342601(CHEMBL1255901 | Huperzine A)
Affinity DataIC50:  12nMAssay Description:Inhibition of human AChE pre-incubated for 10 mins before acetylthiocholine iodide substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50342601(CHEMBL1255901 | Huperzine A)
Affinity DataIC50:  44.5nMAssay Description:Compound was tested for its ability to inhibit the action of acetylcholinesterase isolated from rat brain cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50342601(CHEMBL1255901 | Huperzine A)
Affinity DataIC50:  45nMAssay Description:Compound was tested for its ability to inhibit the action of acetylcholinesterase isolated from rat brain cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50342601(CHEMBL1255901 | Huperzine A)
Affinity DataIC50:  80nMAssay Description:Acetylcholinesterase inhibitory activity in rat striatal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50342601(CHEMBL1255901 | Huperzine A)
Affinity DataIC50:  80nMAssay Description:In vitro inhibitory activity against Acetylcholinesterase (AChE) using rat brain hippocampal crude homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Mus musculus (mouse))
Ume£

Curated by ChEMBL
LigandPNGBDBM50342601(CHEMBL1255901 | Huperzine A)
Affinity DataIC50:  82nMAssay Description:Inhibition of mouse AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50342601(CHEMBL1255901 | Huperzine A)
Affinity DataIC50:  94nMAssay Description:Inhibitory activity against acetylcholinesterase in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCholinesterase(Homo sapiens (Human))
Alchemical Research

Curated by ChEMBL
LigandPNGBDBM50342601(CHEMBL1255901 | Huperzine A)
Affinity DataIC50:  100nMAssay Description:Inhibition of BChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50342601(CHEMBL1255901 | Huperzine A)
Affinity DataIC50:  114nMAssay Description:Inhibitory potency against acetylcholinesterase (AChE) of rat cortex homogenate with ethopropazine as BChE inhibitorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Mayo Clinic

Curated by ChEMBL
LigandPNGBDBM50342601(CHEMBL1255901 | Huperzine A)
Affinity DataIC50:  114nMAssay Description:Inhibition of rat AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50342601(CHEMBL1255901 | Huperzine A)
Affinity DataIC50:  150nMAssay Description:Inhibitory activity against acetylcholinesterase in human RBCMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50342601(CHEMBL1255901 | Huperzine A)
Affinity DataIC50:  1.35E+5nMAssay Description:Inhibitory potency against rat serum Butyrylcholinesterase with BW284c51 as AChE inhibitorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50342601(CHEMBL1255901 | Huperzine A)
Affinity DataIC50: >1.00E+6nMAssay Description:The compound was tested for Butyrylcholinesterase inhibitory activity in rat striatal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed