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Found 6 of ec50 for monomerid = 50395587
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM50395587(CHEMBL2165126 | UNC10000006 | US9156822, 2)
Affinity DataEC50:  126nMpH: 7.4Assay Description:HEK293T cells co-expressing the cAMP biosensor GloSensor-22F (Promega) and hD2 receptors were seeded (10,000 cells/20 ul/well) into white, clear-bott...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM50395587(CHEMBL2165126 | UNC10000006 | US9156822, 2)
Affinity DataEC50:  3.30nMpH: 7.4Assay Description:Recruitment of β-arrestin to agonist-stimulated D2 receptors was performed using a previously described Tango-type assay (Barnea et al., Proc. N...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM50395587(CHEMBL2165126 | UNC10000006 | US9156822, 2)
Affinity DataEC50:  270nMAssay Description:Partial agonist activity at human D2SR expressed in HEK293T cells co-expressing (EA)beta-arrestin2 and GRK2 assessed as induction of beta-arrestin2 r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM50395587(CHEMBL2165126 | UNC10000006 | US9156822, 2)
Affinity DataEC50:  2nMAssay Description:Partial agonist activity at D2L receptor in human HTLA cells assessed as beta arrestin recruitment at 6 uM after 18 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM50395587(CHEMBL2165126 | UNC10000006 | US9156822, 2)
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at human D2S receptor expressed in HEK293T cell membranes coexpressing Galphao1 assessed as induction of nucleotide exchange preincu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM50395587(CHEMBL2165126 | UNC10000006 | US9156822, 2)
Affinity DataEC50:  2.50E+3nMpH: 7.4Assay Description:Cell Culture: Chinese Hamster Ovary (CHO) cells stably expressing the hD2L dopamine receptor (Urban et al., Neuropsychopharmacology 32:67 (2007)) wer...More data for this Ligand-Target Pair
In DepthDetails US Patent