Compile Data Set for Download or QSAR
maximum 50k data
Found 698 of ic50 for UniProtKB: P10828
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18864(3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]pr...)
Affinity DataIC50:  0.0190nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18864(3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]pr...)
Affinity DataIC50:  0.0191nMAssay Description:Inhibition of thyroid hormone receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18864(3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]pr...)
Affinity DataIC50:  0.0191nMAssay Description:Inhibition of human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18865(3-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy...)
Affinity DataIC50:  0.0250nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18865(3-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy...)
Affinity DataIC50:  0.0251nMAssay Description:Inhibition of human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18865(3-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy...)
Affinity DataIC50:  0.0251nMAssay Description:Inhibition of thyroid hormone receptor betaMore data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18862(2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]ac...)
Affinity DataIC50:  0.0407nMAssay Description:Inhibition of thyroid hormone receptor betaMore data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18862(2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]ac...)
Affinity DataIC50:  0.0479nMAssay Description:Inhibition of human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18862(2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]ac...)
Affinity DataIC50:  0.0480nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM50123058(2-(3,5-dichloro-4-(4-hydroxy-3-(piperidin-1-ylsulf...)
Affinity DataIC50:  0.0562nMAssay Description:Inhibition of human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM50178975(4,6-dichloro-5-(4-hydroxy-3-isopropylphenoxy)-1H-i...)
Affinity DataIC50:  0.0600nMAssay Description:Inhibition of human TRbeta1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM50178975(4,6-dichloro-5-(4-hydroxy-3-isopropylphenoxy)-1H-i...)
Affinity DataIC50:  0.0603nMAssay Description:Inhibition of thyroid hormone receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM254887(US9493472, 10)
Affinity DataIC50:  0.0900nMAssay Description:Inhibition of purified human plasma thrombin using Boc-Asp(OBzl)-Pro-Arg-AMC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18867(2-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy...)
Affinity DataIC50:  0.0950nM EC50:  0.200nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18867(2-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy...)
Affinity DataIC50:  0.0950nM EC50:  0.200nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18867(2-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy...)
Affinity DataIC50:  0.0955nMAssay Description:Inhibition of thyroid hormone receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18867(2-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy...)
Affinity DataIC50:  0.0955nMAssay Description:Inhibition of human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18867(2-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy...)
Affinity DataIC50:  0.100nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM398047(US10322118, Entry 5)
Affinity DataIC50:  0.103nMAssay Description:Agonist activity at GAL4 DNA-binding domain fused TRbeta receptor (unknown origin) ligand binding domain expressed in UAS-bla HEK 293T cells assessed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18863((2R)-2-amino-3-{4-[4-hydroxy-3-(propan-2-yl)phenox...)
Affinity DataIC50:  0.110nMAssay Description:Inhibition of thyroid hormone receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18863((2R)-2-amino-3-{4-[4-hydroxy-3-(propan-2-yl)phenox...)
Affinity DataIC50:  0.110nMAssay Description:Inhibition of human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18863((2R)-2-amino-3-{4-[4-hydroxy-3-(propan-2-yl)phenox...)
Affinity DataIC50:  0.110nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM50123044(5-(2,6-dichloro-4-(3,5-dioxo-4,5-dihydro-1,2,4-tri...)
Affinity DataIC50:  0.112nMAssay Description:Inhibition of human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM50123044(5-(2,6-dichloro-4-(3,5-dioxo-4,5-dihydro-1,2,4-tri...)
Affinity DataIC50:  0.112nMAssay Description:Inhibition of human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18870(3-{3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenox...)
Affinity DataIC50:  0.150nM EC50:  0.280nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18870(3-{3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenox...)
Affinity DataIC50:  0.151nMAssay Description:Inhibition of thyroid hormone receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18870(3-{3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenox...)
Affinity DataIC50:  0.151nMAssay Description:Inhibition of human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM50123045(CHEMBL413699 | N-Cyclohexyl-5-[2,6-dichloro-4-(3,5...)
Affinity DataIC50:  0.195nMAssay Description:Inhibition of human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18913(2-{3,5-dichloro-4-[3-(3-ethylphenyl)-4-hydroxyphen...)
Affinity DataIC50:  0.200nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18913(2-{3,5-dichloro-4-[3-(3-ethylphenyl)-4-hydroxyphen...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of thyroid hormone receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18913(2-{3,5-dichloro-4-[3-(3-ethylphenyl)-4-hydroxyphen...)
Affinity DataIC50:  0.200nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataIC50:  0.257nMAssay Description:Inhibition of human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataIC50:  0.260nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataIC50:  0.260nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataIC50:  0.260nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to r...More data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataIC50:  0.260nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM50178971((R)-2-Amino-3-[4-(4-hydroxy-3-iodo-phenoxy)-3,5-di...)
Affinity DataIC50:  0.260nMAssay Description:Inhibition of human TRbeta1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataIC50:  0.260nMAssay Description:Inhibitory concentration against cloned human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM50178971((R)-2-Amino-3-[4-(4-hydroxy-3-iodo-phenoxy)-3,5-di...)
Affinity DataIC50:  0.263nMAssay Description:Inhibition of thyroid hormone receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM50547821(CHEMBL4761137)
Affinity DataIC50:  0.270nMAssay Description:Inhibition of purified human plasma thrombin using Boc-Asp(OBzl)-Pro-Arg-AMC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM18874((2S)-2-(1-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl...)
Affinity DataIC50:  0.270nM EC50:  0.770nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM50178974(4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-1H-in...)
Affinity DataIC50:  0.280nMAssay Description:Inhibition of human TRbeta1 by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM50178974(4,6-dibromo-5-(4-hydroxy-3-isopropylphenoxy)-1H-in...)
Affinity DataIC50:  0.282nMAssay Description:Inhibition of thyroid hormone receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM50123054(5-(2,6-dichloro-4-(3,5-dioxo-4,5-dihydro-1,2,4-tri...)
Affinity DataIC50:  0.282nMAssay Description:Inhibition of human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM254899(US9493472, 21)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of purified human plasma thrombin using Boc-Asp(OBzl)-Pro-Arg-AMC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM50171808(CHEMBL194242 | N-[4-(5-Bromo-6-hydroxy-naphthalen-...)
Affinity DataIC50:  0.300nMAssay Description:Inhibitory concentration against cloned human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM50171802(CHEMBL196642 | N-[3,5-Dichloro-4-(5-isopropyl-6-me...)
Affinity DataIC50:  0.300nMAssay Description:Inhibitory concentration against cloned human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM50171801(CHEMBL198367 | N-[4-(5-Bromo-6-hydroxy-naphthalen-...)
Affinity DataIC50:  0.300nMAssay Description:Inhibitory concentration against cloned human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM50123064(2-(3-chloro-4-(4-hydroxy-3-(piperidin-1-ylsulfonyl...)
Affinity DataIC50:  0.363nMAssay Description:Inhibition of human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio

LigandPNGBDBM50547825(CHEMBL4749829)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of purified human plasma thrombin using Boc-Asp(OBzl)-Pro-Arg-AMC substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
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