Compile Data Set for Download or QSAR
maximum 50k data
Found 65 of ic50 for UniProtKB: P08581
LigandPNGBDBM588211(US11542259, Compound 5 | methyl 4-[4-[[1-[(4- fluo...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588212(4-[4-[[1-[(4- fluorophenyl)carbamoyl]- cyclopropan...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588213(1-N-[4-(6-carbamoyl-7- methoxyquinolin-4- yl)oxyph...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588214(1-N'-(4-fluorophenyl)-1-N- [4-[7-methoxy-6- (methy...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588215(1-N-[4-[6-[2- (dimethylamino)ethylcarbamoyl]- 7-me...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588216(1-N'-(4-fluorophenyl)-N-[4-[7- methoxy-6-(2-piperi...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588217(1-N'-(4-fluorophenyl)-1-N- [4-[7-methoxy-6-(2-morp...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588218(1-N'-(4-fluorophenyl)-1-N- [4-[7-methoxy-6-(oxetan...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588219(1-N'-(4-fluorophenyl)-1-N- [4-[7-methoxy-6- [(1-me...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588221(1-N'-(4-fluorophenyl)-1-N- [4-[6-(3-hydroxyazetidi...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588222(1-N'-(4-fluorophenyl)-1-N- [4-[7-methoxy-6- [[(2R)...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588223(1-N'-(4-fluorophenyl)-1-N- [4-[7-methoxy-6- [[(2S)...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588225(1-N'-(4-fluorophenyl)-1-N- [4-[7-methoxy-6-(1,3-ox...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588232(1-N-[4-[6-carbamoyl-7-(3- morpholin-4- ylpropoxy)q...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588233(1-N-[4-[6-carbamoyl-7-(2- methoxyethoxy)quinolin-4...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588234(US11542259, Compound 128 | methyl 4-[2-chloro-4-[[...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588236(1-N'-[4-(6-carbamoyl-7- methoxyquinolin-4-yl)oxy-3...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588237(1-N'-[3-chloro-4-[7-methoxy-6 (methylcarbamoyl)qui...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588238(US11542259, Compound 129 | methyl 4-[2-fluoro-4-[[...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588239(4-[2-fluoro-4-[[1-[(4- fluorophenyl)carbamoyl]- cy...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588240(1-N'-[4-(6-carbamoyl-7- methoxyquinolin-4-yl)oxy-3...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588241(1-N'-[3-fluoro-4-[7-methoxy-6 (methylcarbamoyl)qui...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588244(1-N-[4-(7-carbamoyl-6- methylquinolin-4-yl)oxyphen...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588245(1-N'-(4-fluorophenyl)-1-N- [4-[6-methyl-7- (methyl...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588246(US11542259, Compound 150 | methyl 4-[4-[[1-[(4- fl...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588248(1-N-[4-(7-carbamoyl-6- methoxyquinolin-4- yl)oxyph...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588252(1-N-[4-(7-carbamoylquinolin- 4-yl)oxyphenyl]-1-N'-...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588253(1-N'-(4-fluorophenyl)-1-N-[4- [7-(methylcarbamoyl)...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588258(1-N'-(4-fluorophenyl)-1-N- [4-[7-methoxy-6- (1-met...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588259(1-N'-(4-fluorophenyl)-1-N- [4-[7-methoxy-6- (1,2-o...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588261(1-N'-(4-fluorophenyl)-1-N- [4-[7-methoxy-6-(1H-pyr...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588262(1-N'-(4-fluorophenyl)-1-N- [4-[7-methoxy-6- (1H-py...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588264(1-N'-(4-fluorophenyl)-1-N- [4-[7-methoxy-6- (1H-py...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588266(1-N'-(4-fluorophenyl)-1-N- [4-[6-(3-hydroxyoxetan-...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588267(1-N'-(4-fluorophenyl)-1-N- [4-[6-(3-hydroxyazetidi...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588269(1-N'-(4-fluorophenyl)-1-N- [4-[6-(3-hydroxyazetidi...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588271(1-N'-(4-fluorophenyl)-1-N-[4-(7- methoxy-6-pyridin...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588272(1-N'-(4-fluorophenyl)-1-N-[4-(7- methoxy-6-pyridin...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588273(1-N'-(4-fluorophenyl)-1-N-[4-(7- methoxy-6-sulfamo...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588274(1-N'-(4-fluorophenyl)-1-N-[4-(7- methoxy-6- methyl...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588275(1-N'-(4-fluorophenyl)-1-N-[4-[7- methoxy-6-(1,3,4-...)
Affinity DataIC50: <10nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588220(1-N-[4-[6-(azetidine-1- carbonyl)-7-methoxyquinoli...)
Affinity DataIC50:  55nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588270(1-N-[4-[6-(3,3-difluoroazetidin- 1-yl)-7-methoxyqu...)
Affinity DataIC50:  55nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588226(1-N-[4-(6-carbamoylquinolin- 4-yl)oxyphenyl]-1-N'-...)
Affinity DataIC50:  55nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588227(1-N'-(4-fluorophenyl)-1-N- [4-[6- (methylcarbamoyl...)
Affinity DataIC50:  55nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588228(1-N'-(4-fluorophenyl)-1-N- [4-[6-[(1-methylazetidi...)
Affinity DataIC50:  55nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588229(1-N-[4-(6-carbamoyl-7- fluoroquinolin-4-yl)oxyphen...)
Affinity DataIC50:  55nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588230(1-N-[4-(6-carbamoyl-7- chloroquinolin-4-yl)- oxyph...)
Affinity DataIC50:  55nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588231(1-N-[4-(7-bromo-6- carbamoylquinolin-4- yl)oxyphen...)
Affinity DataIC50:  55nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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LigandPNGBDBM588235(4-[2-chloro-4-[[1-[(4- fluorophenyl)carbamoyl]- cy...)
Affinity DataIC50:  55nMAssay Description:Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM KKKGQEEEYVFIE (SEO ID NO...More data for this Ligand-Target Pair
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