Compile Data Set for Download or QSAR
maximum 50k data
Found 46 of ic50 for UniProtKB: P10827
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18815(1-(4-hexylphenyl)-3-[(2-hydroxyethyl)(methyl)amino...)
Affinity DataIC50:  3.00E+3nMpH: 7.2 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18814(1-(4-hexylphenyl)-3-[methyl(2-phenylethyl)amino]pr...)
Affinity DataIC50:  3.60E+3nMpH: 7.2 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18816(3-[bis(propan-2-yl)amino]-1-(4-hexylphenyl)propan-...)
Affinity DataIC50:  4.10E+3nMpH: 7.2 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18818(1-(4-hexylphenyl)-3-(morpholin-4-yl)propan-1-one |...)
Affinity DataIC50:  4.10E+3nMpH: 7.2 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18857(3-bromo-1-(4-hexylphenyl)propan-1-one | beta-bromo...)
Affinity DataIC50:  4.20E+3nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18817(1-(4-hexylphenyl)-3-(pyrrolidin-1-yl)propan-1-one ...)
Affinity DataIC50:  4.30E+3nMpH: 7.2 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18819(beta-Aminophenylketone, 3f | methyl 1-[3-(4-hexylp...)
Affinity DataIC50:  6.30E+3nMpH: 7.2 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18820(3-(dibutylamino)-1-(4-hexylphenyl)propan-1-one | b...)
Affinity DataIC50:  6.90E+3nMpH: 7.2 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18821(3-(dimethylamino)-1-(4-hexylphenyl)propan-1-one | ...)
Affinity DataIC50:  1.06E+4nMpH: 7.2 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18823(3-(dicyclohexylamino)-1-(4-hexylphenyl)propan-1-on...)
Affinity DataIC50:  1.65E+4nMpH: 7.2 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18854(4-hexylphenyl prop-2-ynoate | Propiolic acid deriv...)
Affinity DataIC50:  1.67E+4nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18847((2Z)-3-[(4-hexylphenyl)carbamoyl]prop-2-enoic acid...)
Affinity DataIC50:  1.75E+4nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18827((2E)-1-(4-heptylphenyl)but-2-en-1-one | Enone, 4b)
Affinity DataIC50:  1.89E+4nMpH: 7.2 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18826((2E)-4-(4-hexylphenyl)-4-oxobut-2-enoic acid | Eno...)
Affinity DataIC50:  1.92E+4nMpH: 7.2 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18839(4-octylphenyl prop-2-enoate | Substituted Acrylate...)
Affinity DataIC50:  2.14E+4nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18846(N-(4-hexylphenyl)prop-2-enamide | Substituted Acry...)
Affinity DataIC50:  2.16E+4nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18822(3-[(furan-2-ylmethyl)(methyl)amino]-1-(4-hexylphen...)
Affinity DataIC50:  2.26E+4nMpH: 7.2 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18838(4-heptylphenyl prop-2-enoate | Substituted Acrylat...)
Affinity DataIC50:  2.30E+4nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18824(1-(4-hexylphenyl)-3-(propylamino)propan-1-one | be...)
Affinity DataIC50:  2.58E+4nMpH: 7.2 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18825(1-(4-hexylphenyl)prop-2-en-1-one | Enone, 1)
Affinity DataIC50:  2.81E+4nMpH: 7.2 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18859(2-[(4-hexylphenyl)carbonyl]oxirane | epoxy-ketone,...)
Affinity DataIC50:  3.32E+4nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18843(Substituted Acrylate, 6k | hexyl 2-(prop-2-enoylox...)
Affinity DataIC50:  3.91E+4nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18837(4-hexylphenyl prop-2-enoate | Substituted Acrylate...)
Affinity DataIC50:  4.52E+4nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18855(2-chloro-1-(4-hexylphenyl)ethan-1-one | alpha-chlo...)
Affinity DataIC50:  4.77E+4nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18828(1-(4-heptylphenyl)-2-methylprop-2-en-1-one | Enone...)
Affinity DataIC50:  5.29E+4nMpH: 7.2 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18835(4-pentylphenyl prop-2-enoate | Substituted Acrylat...)
Affinity DataIC50:  6.09E+4nMpH: 7.2 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18853(N-(4-hexylphenyl)prop-2-ynamide | Propiolic acid d...)
Affinity DataIC50:  6.89E+4nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18836(4-(2-methylbutan-2-yl)phenyl prop-2-enoate | Subst...)
Affinity DataIC50:  6.96E+4nMpH: 7.2 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18834(4-butylphenyl prop-2-enoate | Substituted Acrylate...)
Affinity DataIC50:  7.10E+4nMpH: 7.2 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18840(4-(2-methylbutan-2-yl)cyclohexyl prop-2-enoate | S...)
Affinity DataIC50:  7.56E+4nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18845(5,6,7,8-tetrahydronaphthalen-2-yl prop-2-enoate | ...)
Affinity DataIC50:  8.53E+4nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18848((2E)-N-(4-hexylphenyl)but-2-enamide | Substituted ...)
Affinity DataIC50: >1.00E+5nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18849(N-(4-hexylphenyl)-3-methylbut-2-enamide | Substitu...)
Affinity DataIC50: >1.00E+5nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18841(Substituted Acrylate, 6i | propyl 4-(prop-2-enoylo...)
Affinity DataIC50: >1.00E+5nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18851(3-[(4-hexylphenyl)carbamoyl]-2-methylidenepropanoi...)
Affinity DataIC50: >1.00E+5nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18832(1-(4-hexylphenyl)propan-1-one | Enone, 4g)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18831((2E)-1-(4-heptylphenyl)-3-phenylprop-2-en-1-one | ...)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18830((2E)-1-(4-heptylphenyl)-2-methylbut-2-en-1-one | E...)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18852(3-[(4-hexylphenyl)carbamoyl]propanoic acid | Subst...)
Affinity DataIC50: >1.00E+5nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18856(2-fluoro-1-(4-hexylphenyl)ethan-1-one | alpha-fluo...)
Affinity DataIC50: >1.00E+5nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18829(1-(4-heptylphenyl)-3-methylbut-2-en-1-one | Enone,...)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18858(4-bromo-1-(4-hexylphenyl)butan-1-one | gamma-bromo...)
Affinity DataIC50: >1.00E+5nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18833(4-propylphenyl prop-2-enoate | Substituted Acrylat...)
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18844(4-butanamidophenyl prop-2-enoate | Substituted Acr...)
Affinity DataIC50: >1.00E+5nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18842(Substituted Acrylate, 6j | pentyl 4-(prop-2-enoylo...)
Affinity DataIC50: >1.00E+5nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha [148-410](Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM18850((2E)-N-(4-hexylphenyl)-3-phenylprop-2-enamide | Su...)
Affinity DataIC50: >1.00E+5nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed