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Found 1869 of ic50 for UniProtKB: P49327
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50124410(CHEMBL3623457)
Affinity DataIC50:  3nMAssay Description:Inhibition of fatty acid synthase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM128366(US8802864, 132)
Affinity DataIC50:  3nMpH: 7.0Assay Description:Assay #1:Inhibition of FAS activity can be measured based on the detection of residual NADPH substrate after the FAS assay is quenched. This assay is...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM128362(US8802864, 42)
Affinity DataIC50:  5nMpH: 7.0Assay Description:Assay #1:Inhibition of FAS activity can be measured based on the detection of residual NADPH substrate after the FAS assay is quenched. This assay is...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244437(US10226449, cpd 46 | US9428502, 46)
Affinity DataIC50:  5nMAssay Description:FASN activity of the SKBr3 cell extract was determined by measuring either NADPH oxidation or the amount of thiol-containing coenzyme A (CoA) release...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244437(US10226449, cpd 46 | US9428502, 46)
Affinity DataIC50:  5nMT: 2°CAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM128359(US8802864, 14)
Affinity DataIC50:  6nMpH: 7.0Assay Description:Assay #1:Inhibition of FAS activity can be measured based on the detection of residual NADPH substrate after the FAS assay is quenched. This assay is...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244398(US10226449, cpd 7 | US9428502, 7)
Affinity DataIC50:  6nMT: 2°CAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244404(US10226449, cpd 13 | US9428502, 13)
Affinity DataIC50:  6nMT: 2°CAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244404(US10226449, cpd 13 | US9428502, 13)
Affinity DataIC50:  6nMAssay Description:FASN activity of the SKBr3 cell extract was determined by measuring either NADPH oxidation or the amount of thiol-containing coenzyme A (CoA) release...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50391838(CHEMBL2147033)
Affinity DataIC50:  6nMAssay Description:Inhibition of fatty acid synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244398(US10226449, cpd 7 | US9428502, 7)
Affinity DataIC50:  6nMAssay Description:FASN activity of the SKBr3 cell extract was determined by measuring either NADPH oxidation or the amount of thiol-containing coenzyme A (CoA) release...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50124413(CHEMBL3623460)
Affinity DataIC50:  6nMAssay Description:Inhibition of fatty acid synthase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244438(US10226449, cpd 47 | US9428502, 47)
Affinity DataIC50:  7nMT: 2°CAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244435(US10226449, cpd 44 | US9428502, 44)
Affinity DataIC50:  7nMAssay Description:FASN activity of the SKBr3 cell extract was determined by measuring either NADPH oxidation or the amount of thiol-containing coenzyme A (CoA) release...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244435(US10226449, cpd 44 | US9428502, 44)
Affinity DataIC50:  7nMT: 2°CAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244438(US10226449, cpd 47 | US9428502, 47)
Affinity DataIC50:  7nMAssay Description:FASN activity of the SKBr3 cell extract was determined by measuring either NADPH oxidation or the amount of thiol-containing coenzyme A (CoA) release...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM119133((S)-4-(4-(Benzofuran-5-yl)phenyl)-3-((1-(cycloprop...)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of FAS by GSK2194069 was measured by an endpoint assay for thiols using a fluorescent maleimide.More data for this Ligand-Target Pair
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50124411(CHEMBL3623458)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of fatty acid synthase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244581(US10226449, cpd 190 | US9428502, 190)
Affinity DataIC50:  8nMAssay Description:FASN activity of the SKBr3 cell extract was determined by measuring either NADPH oxidation or the amount of thiol-containing coenzyme A (CoA) release...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244581(US10226449, cpd 190 | US9428502, 190)
Affinity DataIC50:  8nMT: 2°CAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244418(US10226449, cpd 27 | US9428502, 27)
Affinity DataIC50:  9nMT: 2°CAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244769(US10226449, cpd 381 | US9428502, 381)
Affinity DataIC50:  9nMAssay Description:FASN activity of the SKBr3 cell extract was determined by measuring either NADPH oxidation or the amount of thiol-containing coenzyme A (CoA) release...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244439(US10226449, cpd 48 | US9428502, 48)
Affinity DataIC50:  9nMT: 2°CAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244440(US10226449, cpd 49 | US9428502, 49)
Affinity DataIC50:  9nMT: 2°CAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244575(US10226449, cpd 184 | US9428502, 184)
Affinity DataIC50:  9nMT: 2°CAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244632(US10226449, cpd 241 | US9428502, 241)
Affinity DataIC50:  9nMT: 2°CAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244743(US10226449, cpd 353 | US9428502, 353)
Affinity DataIC50:  9nMT: 2°CAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244769(US10226449, cpd 381 | US9428502, 381)
Affinity DataIC50:  9nMT: 2°CAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244418(US10226449, cpd 27 | US9428502, 27)
Affinity DataIC50:  9nMAssay Description:FASN activity of the SKBr3 cell extract was determined by measuring either NADPH oxidation or the amount of thiol-containing coenzyme A (CoA) release...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244436(US10226449, cpd 45 | US9428502, 45)
Affinity DataIC50:  9nMAssay Description:FASN activity of the SKBr3 cell extract was determined by measuring either NADPH oxidation or the amount of thiol-containing coenzyme A (CoA) release...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244439(US10226449, cpd 48 | US9428502, 48)
Affinity DataIC50:  9nMAssay Description:FASN activity of the SKBr3 cell extract was determined by measuring either NADPH oxidation or the amount of thiol-containing coenzyme A (CoA) release...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244440(US10226449, cpd 49 | US9428502, 49)
Affinity DataIC50:  9nMAssay Description:FASN activity of the SKBr3 cell extract was determined by measuring either NADPH oxidation or the amount of thiol-containing coenzyme A (CoA) release...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244575(US10226449, cpd 184 | US9428502, 184)
Affinity DataIC50:  9nMAssay Description:FASN activity of the SKBr3 cell extract was determined by measuring either NADPH oxidation or the amount of thiol-containing coenzyme A (CoA) release...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244632(US10226449, cpd 241 | US9428502, 241)
Affinity DataIC50:  9nMAssay Description:FASN activity of the SKBr3 cell extract was determined by measuring either NADPH oxidation or the amount of thiol-containing coenzyme A (CoA) release...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244743(US10226449, cpd 353 | US9428502, 353)
Affinity DataIC50:  9nMAssay Description:FASN activity of the SKBr3 cell extract was determined by measuring either NADPH oxidation or the amount of thiol-containing coenzyme A (CoA) release...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244436(US10226449, cpd 45 | US9428502, 45)
Affinity DataIC50:  9nMT: 2°CAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM119133((S)-4-(4-(Benzofuran-5-yl)phenyl)-3-((1-(cycloprop...)
Affinity DataIC50:  10nMpH: 7.0Assay Description:Assay #1:Inhibition of FAS activity can be measured based on the detection of residual NADPH substrate after the FAS assay is quenched. This assay is...More data for this Ligand-Target Pair
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50526389(CHEMBL4450081)
Affinity DataIC50:  10nMAssay Description:Inhibition of full length recombinant human FASN using acetyl-CoA/malonyl-CoA as substrate preincubated for 60 mins followed by substrate addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM137324(US8871790, 410)
Affinity DataIC50:  10nMAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM137333(US8871790, 419)
Affinity DataIC50:  10nMAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244396(US10226449, cpd 5 | US9428502, 5)
Affinity DataIC50:  10nMT: 2°CAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244595(US10226449, cpd 204 | US9428502, 204)
Affinity DataIC50:  10nMT: 2°CAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244629(US10226449, cpd 238 | US9428502, 238)
Affinity DataIC50:  10nMT: 2°CAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244722(US10226449, cpd 332 | US9428502, 332)
Affinity DataIC50:  10nMT: 2°CAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50124414(CHEMBL3623461)
Affinity DataIC50:  10nMAssay Description:Inhibition of fatty acid synthase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50391837(CHEMBL2147032)
Affinity DataIC50:  10nMAssay Description:Inhibition of fatty acid synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244396(US10226449, cpd 5 | US9428502, 5)
Affinity DataIC50:  10nMAssay Description:FASN activity of the SKBr3 cell extract was determined by measuring either NADPH oxidation or the amount of thiol-containing coenzyme A (CoA) release...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244595(US10226449, cpd 204 | US9428502, 204)
Affinity DataIC50:  10nMAssay Description:FASN activity of the SKBr3 cell extract was determined by measuring either NADPH oxidation or the amount of thiol-containing coenzyme A (CoA) release...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244629(US10226449, cpd 238 | US9428502, 238)
Affinity DataIC50:  10nMAssay Description:FASN activity of the SKBr3 cell extract was determined by measuring either NADPH oxidation or the amount of thiol-containing coenzyme A (CoA) release...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM244722(US10226449, cpd 332 | US9428502, 332)
Affinity DataIC50:  10nMAssay Description:FASN activity of the SKBr3 cell extract was determined by measuring either NADPH oxidation or the amount of thiol-containing coenzyme A (CoA) release...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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