TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: 80nMAssay Description:Inhibition of PLK1-mediated mitosis in human HeLaS3 cells after 18 hrsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: 200nMAssay Description:Inhibition of PLK1 in thymidine synchronized human HeLa cells using casein as substrate preincubated with compound for 13 hrs followed by substrate a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: 210nMAssay Description:Inhibition of PLK1-mediated mitosis in human HeLaS3 cells after 18 hrsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: 310nMAssay Description:Inhibition of PLK1-mediated mitosis in human HeLaS3 cells after 18 hrsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: 614nMAssay Description:List of compounds to be tested: Compounds that met the active criterion of Z-score is = -3 in the in vitro PLK1-PBD binding primary screen AID 693,...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: 650nMAssay Description:Binding affinity to PLK1 in human PC-3 cells incubated for 2 hrs followed by heat shock for 10 mins by cellular thermal shift assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: 723nMAssay Description:List of compounds to be tested: Compounds that met the active criterion of Z-score is = -3 in the in vitro PLK1-PBD binding primary screen AID 693,...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: 820nMAssay Description:Binding affinity to full length PLK1 in human PC-3 cells assessed as stabilized protein incubated for 2 hrs followed by aggregation temperature at 56...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: 1.05E+3nMAssay Description:Inhibition of PLK1 in human MIAPaCa2 cells after 48 hrs by MTT assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: 1.15E+3nMAssay Description:Inhibition of PLK1-mediated mitosis in human HeLaS3 cells after 18 hrsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: 1.16E+3nMAssay Description:Inhibition of PLK1-mediated mitosis in human HeLaS3 cells after 18 hrsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: 1.47E+3nMAssay Description:Inhibition of PLK1 in human MIAPaCa2 cells after 48 hrs by MTT assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: 1.47E+3nMAssay Description:Inhibition of PLK1 in human MIAPaCa2 cells after 48 hrs by MTT assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: 1.58E+3nMAssay Description:List of compounds to be tested: Compounds that met the active criterion of Z-score is = -3 in the in vitro PLK1-PBD binding primary screen AID 693,...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: 1.61E+3nMAssay Description:Inhibition of PLK1 in human MIAPaCa2 cells after 48 hrs by MTT assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: 2.00E+3nMAssay Description:Inhibition of PLK1-mediated mitosis in human HeLaS3 cells after 18 hrsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: 2.55E+3nMAssay Description:Inhibition of PLK1 in human MIAPaCa2 cells after 48 hrs by MTT assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: 2.86E+3nMAssay Description:Inhibition of PLK1 in human MIAPaCa2 cells after 48 hrs by MTT assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: 2.86E+3nMAssay Description:Inhibition of PLK1 in human MIAPaCa2 cells after 48 hrs by MTT assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: 3.75E+3nMAssay Description:Inhibition of PLK1-mediated mitosis in human HeLaS3 cells after 18 hrsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: 5.00E+3nMAssay Description:Inhibition of PLK1 in human MIAPaCa2 cells after 48 hrs by MTT assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: 5.00E+3nMAssay Description:Inhibition of PLK1-mediated mitosis in human HeLaS3 cells after 18 hrsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: 8.28E+3nMAssay Description:Inhibition of PLK1 in human MIAPaCa2 cells after 48 hrs by MTT assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: 8.32E+3nMAssay Description:Inhibition of PLK1 in human MIAPaCa2 cells after 48 hrs by MTT assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: 8.89E+3nMAssay Description:Inhibition of PLK1 in human MIAPaCa2 cells after 48 hrs by MTT assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: 1.33E+4nMAssay Description:List of compounds to be tested: Compounds that met the active criterion of Z-score is = -3 in the in vitro PLK1-PBD binding primary screen AID 693,...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: 1.90E+4nMAssay Description:Inhibition of PLK1-mediated mitosis in human HeLaS3 cells after 18 hrsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: 2.82E+4nMAssay Description:List of compounds to be tested: Compounds that met the active criterion of Z-score is = -3 in the in vitro PLK1-PBD binding primary screen AID 693,...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: 2.91E+4nMAssay Description:List of compounds to be tested: Compounds that met the active criterion of Z-score is = -3 in the in vitro PLK1-PBD binding primary screen AID 693,...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of PLK1 in human MIAPaCa2 cells after 48 hrs by MTT assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of PLK1 in human MIAPaCa2 cells after 48 hrs by MTT assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: 3.60E+4nMAssay Description:Inhibition of PLK1-mediated mitosis in human HeLaS3 cells after 18 hrsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: 3.70E+4nMAssay Description:Inhibition of PLK1-mediated mitosis in human HeLaS3 cells after 18 hrsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: 4.80E+4nMAssay Description:Inhibition of PLK1-mediated mitosis in human HeLaS3 cells after 18 hrsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: 4.80E+4nMAssay Description:Inhibition of PLK1-mediated mitosis in human HeLaS3 cells after 18 hrsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: >5.00E+4nMAssay Description:List of compounds to be tested: Compounds that met the active criterion of Z-score is = -3 in the in vitro PLK1-PBD binding primary screen AID 693,...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: >5.00E+4nMAssay Description:List of compounds to be tested: Compounds that met the active criterion of Z-score is = -3 in the in vitro PLK1-PBD binding primary screen AID 693,...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: >5.00E+4nMAssay Description:List of compounds to be tested: Compounds that met the active criterion of Z-score is = -3 in the in vitro PLK1-PBD binding primary screen AID 693,...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: >5.00E+4nMAssay Description:List of compounds to be tested: Compounds that met the active criterion of Z-score is = -3 in the in vitro PLK1-PBD binding primary screen AID 693,...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: >5.00E+4nMAssay Description:List of compounds to be tested: Compounds that met the active criterion of Z-score is = -3 in the in vitro PLK1-PBD binding primary screen AID 693,...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: >5.00E+4nMAssay Description:List of compounds to be tested: Compounds that met the active criterion of Z-score is = -3 in the in vitro PLK1-PBD binding primary screen AID 693,...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: >5.00E+4nMAssay Description:List of compounds to be tested: Compounds that met the active criterion of Z-score is = -3 in the in vitro PLK1-PBD binding primary screen AID 693,...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: >5.00E+4nMAssay Description:List of compounds to be tested: Compounds that met the active criterion of Z-score is = -3 in the in vitro PLK1-PBD binding primary screen AID 693,...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: >5.00E+4nMAssay Description:List of compounds to be tested: Compounds that met the active criterion of Z-score is = -3 in the in vitro PLK1-PBD binding primary screen AID 693,...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: >5.00E+4nMAssay Description:List of compounds to be tested: Compounds that met the active criterion of Z-score is = -3 in the in vitro PLK1-PBD binding primary screen AID 693,...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: >5.00E+4nMAssay Description:List of compounds to be tested: Compounds that met the active criterion of Z-score is = -3 in the in vitro PLK1-PBD binding primary screen AID 693,...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: >5.00E+4nMAssay Description:List of compounds to be tested: Compounds that met the active criterion of Z-score is = -3 in the in vitro PLK1-PBD binding primary screen AID 693,...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: >5.00E+4nMAssay Description:List of compounds to be tested: Compounds that met the active criterion of Z-score is = -3 in the in vitro PLK1-PBD binding primary screen AID 693,...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: >5.00E+4nMAssay Description:List of compounds to be tested: Compounds that met the active criterion of Z-score is = -3 in the in vitro PLK1-PBD binding primary screen AID 693,...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Banyu Tsukuba Research Institute
Curated by ChEMBL
Banyu Tsukuba Research Institute
Curated by ChEMBL
Affinity DataEC50: >5.00E+4nMAssay Description:List of compounds to be tested: Compounds that met the active criterion of Z-score is = -3 in the in vitro PLK1-PBD binding primary screen AID 693,...More data for this Ligand-Target Pair