TargetGenome polyprotein [1066-1250,R1182K]/[1394-1440,K1405R,D1408E](Dengue virus 2 (strain TSV01))
Novartis Institute For Tropical Diseases
Novartis Institute For Tropical Diseases
Affinity DataIC50: 1.10E+3nM Kd: 7.70E+3nMpH: 7.5 T: 2°CAssay Description:Inhibitors were assayed in a 96-well plate format. Typically, protease was preincubated with concentrations of test compounds at 37 deg C for 30 min....More data for this Ligand-Target Pair
TargetGenome polyprotein [1066-1250,R1182K]/[1394-1440,K1405R,D1408E](Dengue virus 2 (strain TSV01))
Novartis Institute For Tropical Diseases
Novartis Institute For Tropical Diseases
Affinity DataIC50: 1.60E+3nMpH: 7.5 T: 2°CAssay Description:Inhibitors were assayed in a 96-well plate format. Typically, protease was preincubated with concentrations of test compounds at 37 deg C for 30 min....More data for this Ligand-Target Pair
TargetGenome polyprotein [1066-1250,R1182K]/[1394-1440,K1405R,D1408E](Dengue virus 2 (strain TSV01))
Novartis Institute For Tropical Diseases
Novartis Institute For Tropical Diseases
Affinity DataIC50: 2.30E+3nMpH: 7.5 T: 2°CAssay Description:Inhibitors were assayed in a 96-well plate format. Typically, protease was preincubated with concentrations of test compounds at 37 deg C for 30 min....More data for this Ligand-Target Pair
TargetGenome polyprotein [1066-1250,R1182K]/[1394-1440,K1405R,D1408E](Dengue virus 2 (strain TSV01))
Novartis Institute For Tropical Diseases
Novartis Institute For Tropical Diseases
Affinity DataIC50: 5.80E+3nM Kd: 1.86E+4nMpH: 7.5 T: 2°CAssay Description:Inhibitors were assayed in a 96-well plate format. Typically, protease was preincubated with concentrations of test compounds at 37 deg C for 30 min....More data for this Ligand-Target Pair
TargetGenome polyprotein [1066-1250,R1182K]/[1394-1440,K1405R,D1408E](Dengue virus 2 (strain TSV01))
Novartis Institute For Tropical Diseases
Novartis Institute For Tropical Diseases
Affinity DataIC50: 6.00E+3nM Kd: 7.20E+3nMpH: 7.5 T: 2°CAssay Description:Inhibitors were assayed in a 96-well plate format. Typically, protease was preincubated with concentrations of test compounds at 37 deg C for 30 min....More data for this Ligand-Target Pair
TargetGenome polyprotein [1066-1250,R1182K]/[1394-1440,K1405R,D1408E](Dengue virus 2 (strain TSV01))
Novartis Institute For Tropical Diseases
Novartis Institute For Tropical Diseases
Affinity DataIC50: 8.90E+3nMpH: 7.5 T: 2°CAssay Description:Inhibitors were assayed in a 96-well plate format. Typically, protease was preincubated with concentrations of test compounds at 37 deg C for 30 min....More data for this Ligand-Target Pair
TargetGenome polyprotein [1066-1250,R1182K]/[1394-1440,K1405R,D1408E](Dengue virus 2 (strain TSV01))
Novartis Institute For Tropical Diseases
Novartis Institute For Tropical Diseases
Affinity DataIC50: 1.02E+4nM Kd: 1.63E+4nMpH: 7.5 T: 2°CAssay Description:Inhibitors were assayed in a 96-well plate format. Typically, protease was preincubated with concentrations of test compounds at 37 deg C for 30 min....More data for this Ligand-Target Pair
TargetGenome polyprotein [1066-1250,R1182K]/[1394-1440,K1405R,D1408E](Dengue virus 2 (strain TSV01))
Novartis Institute For Tropical Diseases
Novartis Institute For Tropical Diseases
Affinity DataIC50: 2.74E+4nM Kd: 2.29E+4nMpH: 7.5 T: 2°CAssay Description:Inhibitors were assayed in a 96-well plate format. Typically, protease was preincubated with concentrations of test compounds at 37 deg C for 30 min....More data for this Ligand-Target Pair
Affinity DataIC50: 4.82E+4nMpH: 8.5Assay Description:To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...More data for this Ligand-Target Pair
TargetGenome polyprotein [1066-1250,R1182K]/[1394-1440,K1405R,D1408E](Dengue virus 2 (strain TSV01))
Novartis Institute For Tropical Diseases
Novartis Institute For Tropical Diseases
Affinity DataIC50: 5.50E+4nM Kd: 5.40E+4nMpH: 7.5 T: 2°CAssay Description:Inhibitors were assayed in a 96-well plate format. Typically, protease was preincubated with concentrations of test compounds at 37 deg C for 30 min....More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMpH: 8.5Assay Description:To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMpH: 8.5Assay Description:To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMpH: 8.5Assay Description:To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMpH: 8.5Assay Description:To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMpH: 8.5Assay Description:To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMpH: 8.5Assay Description:To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMpH: 8.5Assay Description:To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMpH: 8.5Assay Description:To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMpH: 8.5Assay Description:To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMpH: 8.5Assay Description:To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMpH: 8.5Assay Description:To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMpH: 8.5Assay Description:To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMpH: 8.5Assay Description:To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMpH: 8.5Assay Description:To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMpH: 8.5Assay Description:To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMpH: 8.5Assay Description:To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMpH: 8.5Assay Description:To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...More data for this Ligand-Target Pair
TargetGenome polyprotein [1066-1250,R1182K]/[1394-1440,K1405R,D1408E](Dengue virus 2 (strain TSV01))
Novartis Institute For Tropical Diseases
Novartis Institute For Tropical Diseases
Affinity DataIC50: >1.00E+5nM Kd: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:Inhibitors were assayed in a 96-well plate format. Typically, protease was preincubated with concentrations of test compounds at 37 deg C for 30 min....More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMpH: 8.5Assay Description:To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...More data for this Ligand-Target Pair
Affinity DataIC50: 1.22E+5nMpH: 8.5Assay Description:To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...More data for this Ligand-Target Pair
