Compile Data Set for Download or QSAR
maximum 50k data
Found 17 of ic50 for UniProtKB: P27791
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rattus norvegicus (rat))
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  27nMAssay Description:Inhibition of cAMP-dependent kinase PKA(Protein kinase A) catalytic subunit at 100 uMMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rattus norvegicus (rat))
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM83205((E,2S,3R)-2-amino-4-octadecene-1,3-diol | (E,2S,3R...)
Affinity DataIC50:  98nMAssay Description:Inhibition of cAMP-dependent kinase PKA(Protein kinase A) catalytic subunit at 100 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rattus norvegicus (rat))
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM2691(3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1H-indol-3-...)
Affinity DataIC50:  500nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rattus norvegicus (rat))
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM2684(3-[3-(dimethylamino)propyl]-3,13,23-triazahexacycl...)
Affinity DataIC50:  500nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rattus norvegicus (rat))
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM2685(3-(1H-indol-3-yl)-4-{1-[2-(piperidin-2-yl)ethyl]-1...)
Affinity DataIC50:  1.20E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rattus norvegicus (rat))
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM2687(Bisindolyl deriv. 13 | methyl 3-{3-[4-(1H-indol-3-...)
Affinity DataIC50:  1.50E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rattus norvegicus (rat))
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM2583(3,4-Bis(3-indolyl)-1H-pyrrole-2,5-dione | 3,4-bis(...)
Affinity DataIC50:  2.00E+3nMpH: 7.0 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rattus norvegicus (rat))
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM2694(3-(1H-indol-3-yl)-4-{1-[2-(1-methylpyrrolidin-2-yl...)
Affinity DataIC50:  2.00E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rattus norvegicus (rat))
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
Affinity DataIC50:  2.00E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rattus norvegicus (rat))
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM2692(3-(1H-indol-3-yl)-4-{1-[(1-methylpiperidin-3-yl)me...)
Affinity DataIC50:  2.50E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rattus norvegicus (rat))
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM2693(3-(1H-indol-3-yl)-4-{1-[3-(morpholin-4-yl)propyl]-...)
Affinity DataIC50:  3.00E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rattus norvegicus (rat))
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM2681(3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-(1...)
Affinity DataIC50:  3.50E+3nMpH: 7.0 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rattus norvegicus (rat))
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM2686(3-(1H-indol-3-yl)-4-{1-[3-(piperazin-1-yl)propyl]-...)
Affinity DataIC50:  4.40E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rattus norvegicus (rat))
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM2688(3-(1H-indol-3-yl)-4-[1-(2-methoxyethyl)-1H-indol-3...)
Affinity DataIC50:  4.50E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rattus norvegicus (rat))
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM2682(3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-[1...)
Affinity DataIC50:  6.00E+3nMpH: 7.0 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rattus norvegicus (rat))
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM2690(3-(1-{2-[(dimethylamino)methyl]propyl}-1H-indol-3-...)
Affinity DataIC50:  6.60E+3nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Rattus norvegicus (rat))
Nova Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM2689(3-[1-(3-dymethylaminopropyl)-indol-3-yl]-4-(indol-...)
Affinity DataIC50: >1.00E+4nMAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In DepthDetails PubMed