Compile Data Set for Download or QSAR
maximum 50k data
Found 50 of ki for UniProtKB: P35364
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50371998(CHEMBL404372)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to rat 5HT5A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50051944(3-((1R,2S)-2-Dipropylamino-cyclopropyl)-phenol | C...)
Affinity DataKi:  2.60nMAssay Description:Inhibition of specific [3H]-OH-DPAT binding at 5-hydroxytryptamine 1A receptor in rat hippocampal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50371996(CHEMBL541993)
Affinity DataKi:  2.90nMAssay Description:Binding affinity to rat 5HT5A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50051956(2-((1R,2S)-2-Dipropylamino-cyclopropyl)-phenol | C...)
Affinity DataKi:  4.90nMAssay Description:Inhibition of specific [3H]-OH-DPAT binding at 5-hydroxytryptamine 1A receptor in rat hippocampal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50027065((5'alpha)-12'-hydroxy-2'-methyl-5'-(phenylmethyl)e...)
Affinity DataKi:  6.30nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM21392(3-(2-aminoethyl)-1H-indole-5-carboxamide | 5-CT | ...)
Affinity DataKi:  12.6nMMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50027065((5'alpha)-12'-hydroxy-2'-methyl-5'-(phenylmethyl)e...)
Affinity DataKi:  15.7nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50051950(CHEMBL34652 | [(1S,2R)-2-(2-Methoxy-phenyl)-cyclop...)
Affinity DataKi:  17nMAssay Description:Inhibition of specific [3H]-OH-DPAT binding at 5-hydroxytryptamine 1A receptor in rat hippocampal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM78940(METHIOTHEPIN | MLS000859918 | Methiothepin mesylat...)
Affinity DataKi:  28.8nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50288778(3-((1S,2R)-2-Dipropylaminomethyl-cyclopropyl)-phen...)
Affinity DataKi:  58nMAssay Description:Inhibition of specific [3H]-OH-DPAT binding at 5-hydroxytryptamine 1A receptor in rat hippocampal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM78940(METHIOTHEPIN | MLS000859918 | Methiothepin mesylat...)
Affinity DataKi:  146nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50288773(3-((1S,2S)-2-Dipropylaminomethyl-cyclopropyl)-phen...)
Affinity DataKi:  186nMAssay Description:Inhibition of specific [3H]-OH-DPAT binding at 5-hydroxytryptamine 1A receptor in rat hippocampal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50031942((6aR,9R)-4,6a,7-Trimethyl-4,6,6a,7,8,9-hexahydro-i...)
Affinity DataKi:  195nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50288781(CHEMBL134331 | [(1S,2S)-2-(2-Methoxy-phenyl)-cyclo...)
Affinity DataKi:  239nMAssay Description:Inhibition of specific [3H]-OH-DPAT binding at 5-hydroxytryptamine 1A receptor in rat hippocampal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataKi:  240nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50288780(CHEMBL336124 | [(1S,2S)-2-(3-Methoxy-phenyl)-cyclo...)
Affinity DataKi:  310nMAssay Description:Inhibition of specific [3H]-OH-DPAT binding at 5-hydroxytryptamine 1A receptor in rat hippocampal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50288782(2-((1S,2R)-2-Dipropylaminomethyl-cyclopropyl)-phen...)
Affinity DataKi:  379nMAssay Description:Inhibition of specific [3H]-OH-DPAT binding at 5-hydroxytryptamine 1A receptor in rat hippocampal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50288775(CHEMBL133935 | [(1R,2S)-2-(3-Methoxy-phenyl)-cyclo...)
Affinity DataKi:  388nMAssay Description:Inhibition of specific [3H]-OH-DPAT binding at 5-hydroxytryptamine 1A receptor in rat hippocampal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50288783(CHEMBL423527 | Diethyl-[(1S,2S)-2-(2-methoxy-pheny...)
Affinity DataKi:  431nMAssay Description:Inhibition of specific [3H]-OH-DPAT binding at 5-hydroxytryptamine 1A receptor in rat hippocampal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50288776(2-((1S,2S)-2-Diethylaminomethyl-cyclopropyl)-pheno...)
Affinity DataKi:  506nMAssay Description:Inhibition of specific [3H]-OH-DPAT binding at 5-hydroxytryptamine 1A receptor in rat hippocampal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50288774(CHEMBL334553 | [(1R,2R)-2-(3-Methoxy-phenyl)-cyclo...)
Affinity DataKi:  736nMAssay Description:Inhibition of specific [3H]-OH-DPAT binding at 5-hydroxytryptamine 1A receptor in rat hippocampal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50288779(2-((1S,2S)-2-Dipropylaminomethyl-cyclopropyl)-phen...)
Affinity DataKi:  752nMAssay Description:Inhibition of specific [3H]-OH-DPAT binding at 5-hydroxytryptamine 1A receptor in rat hippocampal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50288777(CHEMBL135894 | [(1R,2S)-2-(2-Methoxy-phenyl)-cyclo...)
Affinity DataKi:  998nMAssay Description:Inhibition of specific [3H]-OH-DPAT binding at 5-hydroxytryptamine 1A receptor in rat hippocampal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50013515((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50013515((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50010301(8-Bromo-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-be...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM35234(DL-[7-3H]norepinephrine | NOREPINEPHRINE | Noradre...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM21393(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50000492((zacopride)4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM21393(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM21393(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM28582(1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine | CHE...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50031942((6aR,9R)-4,6a,7-Trimethyl-4,6,6a,7,8,9-hexahydro-i...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM30704((phenylmethyl) N-[[(6aR,9S,10aR)-4,7-dimethyl-6,6a...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50024204(1H-imidazo[4,5-c]pyridine derivative | 2N-[4,7-dim...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM9019(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50106251(2-(1-Benzenesulfonyl-1H-indol-4-yl)-ethylamine | C...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 5A receptor in HEK 293 cells was determined using [3H]-LSD as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataKi:  1.33E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50106246(CHEMBL126340 | [1-Benzenesulfonyl-4-(2-dimethylami...)
Affinity DataKi:  1.60E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 5A receptor in HEK 293 cells was determined using [3H]-LSD as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50106249(CHEMBL92139 | [2-(1-Benzenesulfonyl-1H-indol-4-yl)...)
Affinity DataKi:  3.40E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 5A receptor in HEK 293 cells was determined using [3H]-LSD as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50106250(CHEMBL93868 | N,N-dimethyl-2-(1-(phenylsulfonyl)-1...)
Affinity DataKi:  4.00E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 5A receptor in HEK 293 cells was determined using [3H]-LSD as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50106252(CHEMBL263700 | [3-(2-Dimethylamino-ethyl)-5-hydrox...)
Affinity DataKi:  4.50E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 5A receptor in HEK 293 cells was determined using [3H]-LSD as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM34141(CHEMBL76237 | MS-245)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 5A receptor in HEK 293 cells was determined using [3H]-LSD as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50106248((4S,5S)-4-Dimethylamino-1-(toluene-4-sulfonyl)-1,3...)
Affinity DataKi: >6.40E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 5A receptor in HEK 293 cells was determined using [3H]-LSD as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A/1B/1D/1F/2A/2B/2C/3A/3B/4/5A/5B/6/7(Rattus norvegicus)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM50231569(Cilansetron | KC-9946)
Affinity DataKi: >1.00E+4nMAssay Description:The binding affinity was measured on 5-hydroxytryptamine receptor uptake receptor using [3H]- paroxetine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50094703(5-(3-Bromo-phenyl)-7-(6-morpholin-4-yl-pyridin-3-y...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM35234(DL-[7-3H]norepinephrine | NOREPINEPHRINE | Noradre...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 1A/1B/1D/1F/2A/2B/2C/3A/3B/4/5A/5B/6/7(Rattus norvegicus)
Solvay Duphar

Curated by ChEMBL
LigandPNGBDBM85330(CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]- GR-65,630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 5A(RAT)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50288772(CHEMBL132580 | [(1R,2R)-2-(2-Methoxy-phenyl)-cyclo...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of specific [3H]-OH-DPAT binding at 5-hydroxytryptamine 1A receptor in rat hippocampal membranesMore data for this Ligand-Target Pair
In DepthDetails Article