Compile Data Set for Download or QSAR
maximum 50k data
Found 25 of ic50 for UniProtKB: P30550
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50158698(CHEMBL266078 | [N40,Pro1,Tyr4]BB)
Affinity DataIC50:  0.0600nMAssay Description:Displacement of [125 I-Tyr4]BB from human gastrin releasing peptide receptor expressed in PC-3 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50158699(CHEMBL414307 | [(N4-Bzdig)0]BB(7-14))
Affinity DataIC50:  0.0800nMAssay Description:Displacement of [125 I-Tyr4]BB from human gastrin releasing peptide receptor expressed in PC-3 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50158697(CHEMBL268222 | [N40,Pro1,Tyr4,Nle 14]BB)
Affinity DataIC50:  0.150nMAssay Description:Displacement of [125 I-Tyr4]BB from human gastrin releasing peptide receptor expressed in PC-3 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50158698(CHEMBL266078 | [N40,Pro1,Tyr4]BB)
Affinity DataIC50:  0.470nMAssay Description:Inhibition of gastrin releasing peptide receptor expressed in human prostate cancer cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50279041((2S)-N1-((5S,8S,11S,17S,20S,23S,26S,29S,35S,38S)-1...)
Affinity DataIC50:  0.590nMAssay Description:Displacement of [125I-Tyr4]BN form BB2 receptor in human PC3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50066009(CHEMBL3401466)
Affinity DataIC50:  0.600nMAssay Description:Displacement of [125I-Tyr4]bombesin from GRPR (unknown origin) expressed in human PC3 cells after 45 mins by gamma counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50158700(CHEMBL266079 | [(N4-Bzdig)0,Nle14]BB(7-14))
Affinity DataIC50:  0.600nMAssay Description:Displacement of [125 I-Tyr4]BB from human gastrin releasing peptide receptor expressed in PC-3 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50158699(CHEMBL414307 | [(N4-Bzdig)0]BB(7-14))
Affinity DataIC50:  0.650nMAssay Description:Inhibition of gastrin releasing peptide receptor expressed in human prostate cancer cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50158702(CHEMBL413893 | Universal ligand)
Affinity DataIC50:  0.720nMAssay Description:Inhibition of gastrin releasing peptide receptor expressed in human prostate cancer cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50158701(CHEMBL407101 | [Tyr4]Bombesin)
Affinity DataIC50:  0.850nMAssay Description:Displacement of [125 I-Tyr4]BB from human gastrin releasing peptide receptor expressed in PC-3 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50279043((S)-N1-((5S,8S,11S,17S,20S,23S,26S,29S,35S,38S)-11...)
Affinity DataIC50:  1.24nMAssay Description:Displacement of [125I-Tyr4]BN form BB2 receptor in human PC3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50158700(CHEMBL266079 | [(N4-Bzdig)0,Nle14]BB(7-14))
Affinity DataIC50:  1.30nMAssay Description:Inhibition of gastrin releasing peptide receptor expressed in human prostate cancer cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50279042((2S)-N1-((5S,8S,11S,17S,20S,23S)-11-((1H-imidazol-...)
Affinity DataIC50:  1.45nMAssay Description:Displacement of [125I-Tyr4]BN form BB2 receptor in human PC3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50158697(CHEMBL268222 | [N40,Pro1,Tyr4,Nle 14]BB)
Affinity DataIC50:  1.94nMAssay Description:Inhibition of gastrin releasing peptide receptor expressed in human prostate cancer cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM85484(Bombesin)
Affinity DataIC50:  2nMAssay Description:Displacement of [125I]-Tyr4-BBN from human GRPR overexpressed in human T47D cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50441006(CHEMBL2429987)
Affinity DataIC50:  5.30nMAssay Description:Displacement of [125I]-Tyr4-bombesin from GRP receptor in human PC3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50441004(CHEMBL2429980)
Affinity DataIC50:  8.30nMAssay Description:Displacement of [125I]-Tyr4-bombesin from GRP receptor in human PC3 cells after 1 hr by gamma-counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50071739((S)-3-(1H-Indol-3-yl)-N-[1-(5-methoxy-pyridin-2-yl...)
Affinity DataIC50:  16nMAssay Description:Antagonistic activity against labelled Bombesin receptor bb2 binding sites in rat cerebral cortex by using [125I]- [Tyr] bombesin in presence of NMB;...More data for this Ligand-Target Pair
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50425231(CHEMBL2314835)
Affinity DataIC50:  18nMAssay Description:Displacement of [125I]-Tyr4-BBN from human GRPR overexpressed in human T47D cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50441003(CHEMBL2429981)
Affinity DataIC50:  23nMAssay Description:Displacement of [125I]-Tyr4-bombesin from GRP receptor in human PC3 cells after 1 hr by gamma-counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50441005(CHEMBL2429964)
Affinity DataIC50:  23nMAssay Description:Binding affinity to GRP receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50314969(2-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)et...)
Affinity DataIC50:  6.40E+3nMAssay Description:Displacement of [125I]D-Tyr6-betaAla11-Phe13-Nle14-bombesin from human GRP-R expressed in NFAT-CHO cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50295236(11-(2-chloro-6-fluorophenyl)-3,3,8-trimethyl-2,3,4...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition gastrin-releasing peptide receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50313710(4'-(2-(5-butyl-1H-imidazol-2-yl)-5-hydroxypentyl)b...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]-[D-Tyr6,beta-Ala11,Phe13,Nle14]bombesin from human bombesin BB2 receptor expressed in NFAT-CHO cells after 2 hrs by liquid sci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
National Center For Scientific Research Demokritos

Curated by ChEMBL
LigandPNGBDBM50336886(1-[4-(2,2-dimethylpropyl)-1H-imidazol-2-yl]-2-[4-(...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human GRPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed