Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at rat GAL4-DBD fused MR ligand binding domain transfected in human Huh7 cells co-expressing GAL4-RE-Luc assessed as reduction in...More data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Antagonist activity at gal4-fused rat mineralocorticoid receptor LBD in expressed in human U2OS cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at gal4-fused rat mineralocorticoid receptor LBD in expressed in human U2OS cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Displacement of [3H]-Aldosterone from MR in rat kidney cytosolic fraction measured after 18 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Displacement of [3H]-aldosterone from rat mineralocorticoid receptor after 18 hrs by liquid scintillation counter analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Displacement of [3H]Aldosterone C from rat mineralocorticoid receptor by liquid scintillation counter analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Displacement of [3H]-Aldosterone from MR in rat renal soluble fraction measured after 18 hrs in presence of glucocorticoid receptor antagonist RU-486...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Displacement of [3H]-Aldosterone from MR in rat renal soluble fraction measured after 18 hrs in presence of glucocorticoid receptor antagonist RU-486...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Antagonist activity at gal4-fused rat mineralocorticoid receptor LBD in expressed in human U2OS cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Displacement of [3H]Aldo from mineralocorticoid receptor in Sprague-Dawley rat kidney after 2 hrs by liquid scintillation countingChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Displacement of [3H]aldosterone from Sprague-Dawley rat MR by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Displacement of [3H]-Aldosterone from MR in rat renal soluble fraction measured after 18 hrs in presence of glucocorticoid receptor antagonist RU-486...More data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Displacement of [3H]-Aldosterone from MR in rat renal soluble fraction measured after 18 hrs in presence of glucocorticoid receptor antagonist RU-486...More data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Antagonist activity at gal4-fused rat mineralocorticoid receptor LBD in expressed in human U2OS cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Antagonist activity at gal4-fused rat mineralocorticoid receptor LBD in expressed in human U2OS cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:Displacement of [3H]-Aldosterone from MR in rat renal soluble fraction measured after 18 hrs in presence of glucocorticoid receptor antagonist RU-486...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]-Aldosterone from MR in rat renal soluble fraction measured after 18 hrs in presence of glucocorticoid receptor antagonist RU-486...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Antagonist activity at gal4-fused rat mineralocorticoid receptor LBD in expressed in human U2OS cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Antagonist activity at gal4-fused rat mineralocorticoid receptor LBD in expressed in human U2OS cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: <500nMAssay Description:Binding affinity to rat mineralocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: <500nMAssay Description:Displacement of [3H]-Aldosterone from MR in Sprague-Dawley rat kidney cytosolic fraction measured after overnight incubation by liquid scintillation ...More data for this Ligand-Target Pair
Affinity DataIC50: <500nMAssay Description:Inhibition of Ha-ras polymerase-chain reaction productMore data for this Ligand-Target Pair
Affinity DataIC50: <500nMAssay Description:Displacement of [3H]-Aldosterone from MR in Sprague-Dawley rat kidney cytosolic fraction measured after overnight incubation by liquid scintillation ...More data for this Ligand-Target Pair
Affinity DataIC50: <500nMAssay Description:Displacement of [3H]-Aldosterone from MR in Sprague-Dawley rat kidney cytosolic fraction measured after overnight incubation by liquid scintillation ...More data for this Ligand-Target Pair
Affinity DataIC50: 580nMAssay Description:Antagonist activity at rat mineralocorticoid receptor-ligand binding domain expressed in AH109 yeast cells co expressing pGADT7-hSRC-1 by two hybrid ...More data for this Ligand-Target Pair
Affinity DataIC50: 820nMAssay Description:Antagonist activity at rat mineralocorticoid receptor-ligand binding domain expressed in AH109 yeast cells co expressing pGADT7-hSRC-1 by two hybrid ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.11E+3nMAssay Description:Antagonist activity at rat mineralocorticoid receptor-ligand binding domain expressed in AH109 yeast cells co expressing pGADT7-hSRC-1 by two hybrid ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Displacement of [3H]Aldo from mineralocorticoid receptor in Sprague-Dawley rat kidney after 2 hrs by liquid scintillation countingChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Displacement of [3H]aldosterone from Sprague-Dawley rat MR by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 2.78E+3nMAssay Description:Antagonist activity at rat mineralocorticoid receptor-ligand binding domain expressed in AH109 yeast cells co expressing pGADT7-hSRC-1 by two hybrid ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Antagonist activity at rat mineralocorticoid receptor-ligand binding domain expressed in AH109 yeast cells co expressing pGADT7-hSRC-1 by two hybrid ...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:The IC50s were determined by incubating the receptors with radiolabeled aldosterone in the presence of full log scale concentrations (10-11 M to 10-6...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:The IC50s were determined by incubating the receptors with radiolabeled aldosterone in the presence of full log scale concentrations (10-11 M to 10-6...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:The IC50s were determined by incubating the receptors with radiolabeled aldosterone in the presence of full log scale concentrations (10-11 M to 10-6...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:The IC50s were determined by incubating the receptors with radiolabeled aldosterone in the presence of full log scale concentrations (10-11 M to 10-6...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:The IC50s were determined by incubating the receptors with radiolabeled aldosterone in the presence of full log scale concentrations (10-11 M to 10-6...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:The IC50s were determined by incubating the receptors with radiolabeled aldosterone in the presence of full log scale concentrations (10-11 M to 10-6...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30E+3nMAssay Description:Displacement of [3H]aldosterone from Sprague-Dawley rat MR by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 6.51E+3nMAssay Description:Antagonist activity at rat mineralocorticoid receptor-ligand binding domain expressed in AH109 yeast cells co expressing pGADT7-hSRC-1 by two hybrid ...More data for this Ligand-Target Pair
Affinity DataIC50: 7.40E+3nMAssay Description:Binding affinity for rat mineralocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 7.56E+3nMAssay Description:Binding affinity for rat mineralocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 8.93E+3nMAssay Description:Antagonist activity at rat mineralocorticoid receptor-ligand binding domain expressed in AH109 yeast cells co expressing pGADT7-hSRC-1 by two hybrid ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity for rat mineralocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity for rat mineralocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity for rat mineralocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity for rat mineralocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+4nMAssay Description:Displacement of [3H]Aldo from mineralocorticoid receptor in Sprague-Dawley rat kidney after 2 hrs by liquid scintillation countingChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.66E+4nMAssay Description:Antagonist activity at rat mineralocorticoid receptor-ligand binding domain expressed in AH109 yeast cells co expressing pGADT7-hSRC-1 by two hybrid ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.17E+4nMAssay Description:Antagonist activity at rat mineralocorticoid receptor-ligand binding domain expressed in AH109 yeast cells co expressing pGADT7-hSRC-1 by two hybrid ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+5nMAssay Description:Displacement of [3H]Aldo from mineralocorticoid receptor in Sprague-Dawley rat kidney after 2 hrs by liquid scintillation countingChecked by AuthorMore data for this Ligand-Target Pair
