Compile Data Set for Download or QSAR
maximum 50k data
Found 47 of ic50 for UniProtKB: P79350
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50013385(CHEMBL166355 | methyl 2-[4-cyclopropylmethyl-10,17...)
Affinity DataIC50:  0.180nMAssay Description:In vitro binding affinity against Opioid receptor mu 1 from bovine caudate nucleus determined in presence of [3H]DAGO (1 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50287332(1N-[4-cyclopropylmethyl-10-hydroxy-(13R,14R)-12-ox...)
Affinity DataIC50:  0.210nMAssay Description:Compound was tested for Inhibition of [3H]-DAMGO (0.25 nM) binding to mu receptor from bovine striatal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50456193(CHEMBL607068)
Affinity DataIC50:  0.280nMAssay Description:Binding affinity against mu opioid receptor from calf frontal cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50013761((R)-1-(3-cyclopropylmethyl-11,15-dimethoxy-13-oxa-...)
Affinity DataIC50:  0.320nMAssay Description:Inhibition of 0.5 nM [3H]- Bremazocine binding to Opioid receptor mu 1 of bovine striatum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50033645(1N-[10-hydroxy-4,13-dimethyl-14-oxo-(13R,17S)-12-o...)
Affinity DataIC50:  0.330nMAssay Description:Binding affinity against mu opioid receptor from calf frontal cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50030143(CHEMBL41098 | bis-(1N-[10-hydroxy-4-methyl-14-oxo-...)
Affinity DataIC50:  0.400nMAssay Description:Inhibitory activity of the compound against Opioid receptor mu 1 binding to bovine striatal membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50030143(CHEMBL41098 | bis-(1N-[10-hydroxy-4-methyl-14-oxo-...)
Affinity DataIC50:  0.400nMAssay Description:Evaluation for the inhibition of mu opioid binding to bovine striatal membranes by the affinity ligand 0.25 nM [3H]DAMGO radiolabeled opioidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50033654(1N-[10-methoxy-4-methyl-14-oxo-(13R,17S)-12-oxa-4-...)
Affinity DataIC50:  0.440nMAssay Description:Binding affinity against mu opioid receptor from calf frontal cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50013388(6-Ethyl-3-(1-hydroxy-cyclopropylmethyl)-11,11-dime...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of 0.5 nM [3H]- Bremazocine binding to Opioid receptor mu 1 of bovine striatum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50033647(1N-[4-cyclopropylmethyl-10-hydroxy-13-methyl-14-ox...)
Affinity DataIC50:  0.520nMAssay Description:Binding affinity against mu opioid receptor from calf frontal cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50287331(1N-[10-hydroxy-4-methyl-(13R,14R)-12-oxa-4-azapent...)
Affinity DataIC50:  0.560nMAssay Description:Compound was tested for Inhibition of [3H]-DAMGO (0.25 nM) binding to mu receptor from bovine striatal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50030144(1N-[10-hydroxy-4-methyl-14-oxo-12-oxa-4-azapentacy...)
Affinity DataIC50:  0.630nMAssay Description:Evaluation for the inhibition of mu opioid binding to bovine striatal membranes by the affinity ligand 0.25 nM [3H]DAMGOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50406411(CHEMBL2021332)
Affinity DataIC50:  0.760nMAssay Description:Inhibition of 0.5 nM [3H]- Bremazocine binding to Opioid receptor mu 1 of bovine striatum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50033648(1N-[10-hydroxy-4,13-dimethyl-14-oxo-(13R,17S)-12-o...)
Affinity DataIC50:  0.800nMAssay Description:Binding affinity against mu opioid receptor from calf frontal cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50013764(5-(3-cyclopropylmethyl-11-hydroxy-15-methoxy-13-ox...)
Affinity DataIC50:  1nMAssay Description:Inhibition of 0.5 nM [3H]- Bremazocine binding to Opioid receptor mu 1 of bovine striatum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50013387(4-cyclopropylmethyl-10,17-dihydroxy-12-oxa-4-azape...)
Affinity DataIC50:  1nMAssay Description:In vitro binding affinity against Opioid receptor mu 1 from bovine caudate nucleus determined in presence of [3H]DAGO (1 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50033642(1N-[10-methoxy-4-methyl-14-oxo-(13R,17S)-12-oxa-4-...)
Affinity DataIC50:  1nMAssay Description:Binding affinity against mu opioid receptor from calf frontal cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50001714(2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(1S,2...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of 0.5 nM [3H]- Bremazocine binding to Opioid receptor mu 1 of bovine striatum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50421363(CHEMBL2304424)
Affinity DataIC50:  1.40nMAssay Description:Inhibitory activity of the compound against Opioid receptor mu 1 binding to bovine striatal membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50033657(1N-[4-cyclopropylmethyl-10-methoxy-14-oxo-(13R,17S...)
Affinity DataIC50:  1.5nMAssay Description:Binding affinity against mu opioid receptor from calf frontal cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50000790(CHEMBL76023 | methyl 2-[4-cyclopropylmethyl-10,17-...)
Affinity DataIC50:  1.5nMAssay Description:In vitro binding affinity against Opioid receptor mu 1 from bovine caudate nucleus determined in presence of [3H]DAGO (1 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50033651(1N-[10-hydroxy-4-methyl-14-oxo-(13R,17S)-12-oxa-4-...)
Affinity DataIC50:  1.5nMAssay Description:Binding affinity against mu opioid receptor from calf frontal cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50013386(4,5alpha-Epoxy-3,6alpha, 14-trihydroxy-6beta-(2-ca...)
Affinity DataIC50:  1.80nMAssay Description:In vitro binding affinity against Opioid receptor mu 1 from bovine caudate nucleus determined in presence of [3H]DAGO (1 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50033656(1N-[4-cyclopropylmethyl-10-hydroxy-13-methyl-14-ox...)
Affinity DataIC50:  1.90nMAssay Description:Binding affinity against mu opioid receptor from calf frontal cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50287045(CHEMBL14680 | N-CBM-TAMO)
Affinity DataIC50:  2nMAssay Description:Compound was tested for binding activity against mu opioid receptor in bovine striatal membranes using 0.25 nM [3H]-DAMGO as the radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50284914(CHEMBL297605 | MET-TAMO and N-CPM-MET-TAMO analogu...)
Affinity DataIC50:  2.90nMAssay Description:Inhibitory activity of the compound against Opioid receptor mu 1 binding to bovine striatal membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50030145(CHEMBL290701 | bis-(1N-[4-cyclopropylmethyl-10-hyd...)
Affinity DataIC50:  3.30nMAssay Description:Evaluation for the inhibition of mu opioid binding to bovine striatal membranes by the affinity ligand 0.25 nM [3H]DAMGO radiolabeled opioidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50030145(CHEMBL290701 | bis-(1N-[4-cyclopropylmethyl-10-hyd...)
Affinity DataIC50:  3.90nMAssay Description:Inhibitory activity of the compound against Opioid receptor mu 1 binding to bovine striatal membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataIC50:  5nMAssay Description:Inhibition of 0.5 nM [3H]- Bremazocine binding to Opioid receptor mu 1 of bovine striatum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50287333(1N-[10-hydroxy-4-methyl-14-oxo-(13R,17S)-12-oxa-4-...)
Affinity DataIC50:  5.80nMAssay Description:Compound was tested for Inhibition of [3H]-DAMGO (0.25 nM) binding to mu receptor from bovine striatal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50013763((S)-19-(1-isothiocyanatoethyl)-15-methoxy-3-methyl...)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of 0.5 nM [3H]- Bremazocine binding to Opioid receptor mu 1 of bovine striatum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50452754(CHEMBL3084322)
Affinity DataIC50:  6.80nMAssay Description:In vitro binding affinity against Opioid receptor mu 1 from bovine caudate nucleus determined in presence of [3H]DAGO (1 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50033653(1N-[4-cyclopropylmethyl-10-hydroxy-14-oxo-(13R,17S...)
Affinity DataIC50:  7.80nMAssay Description:Binding affinity against mu opioid receptor from calf frontal cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50033641(1N-[4-cyclopropylmethyl-10-hydroxy-14-oxo-(13R,17S...)
Affinity DataIC50:  12.1nMAssay Description:Binding affinity against mu opioid receptor from calf frontal cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50287334(1N-[4-cyclopropylmethyl-10-hydroxy-14-oxo-(13R,17S...)
Affinity DataIC50:  24nMAssay Description:Compound was tested for Inhibition of [3H]-DAMGO (0.25 nM) binding to mu receptor from bovine striatal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50033655(1N-[4-cyclopropylmethyl-10-hydroxy-13-methyl-14-ox...)
Affinity DataIC50:  24nMAssay Description:Binding affinity against mu opioid receptor from calf frontal cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50033644(1N-[4-cyclopropylmethyl-10-methoxy-13-methyl-14-ox...)
Affinity DataIC50:  32nMAssay Description:Binding affinity against mu opioid receptor from calf frontal cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50013768(3-O-(tert-Butyldimethylsilyl)-6,14-endo-etheno-7al...)
Affinity DataIC50:  34nMAssay Description:Inhibition of 0.5 nM [3H]- Bremazocine binding to Opioid receptor mu 1 of bovine striatum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50033646(1N-[10-methoxy-4,13-dimethyl-14-oxo-(13R,17S)-12-o...)
Affinity DataIC50:  36nMAssay Description:Binding affinity against mu opioid receptor from calf frontal cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50033650(1N-[4-cyclopropylmethyl-10-methoxy-13-methyl-14-ox...)
Affinity DataIC50:  37nMAssay Description:Binding affinity against mu opioid receptor from calf frontal cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50033652(1N-[4-cyclopropylmethyl-10-methoxy-14-oxo-(13R,17S...)
Affinity DataIC50:  39.1nMAssay Description:Binding affinity against mu opioid receptor from calf frontal cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50406413(CHEMBL2021335)
Affinity DataIC50:  63nMAssay Description:Inhibition of 0.5 nM [3H]- Bremazocine binding to Opioid receptor mu 1 of bovine striatum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50033643(1N-[10-methoxy-4,13-dimethyl-14-oxo-(13R,17S)-12-o...)
Affinity DataIC50:  104nMAssay Description:Binding affinity against mu opioid receptor from calf frontal cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50013769((S)-1-(3-cyclopropylmethyl-11,15-dimethoxy-13-oxa-...)
Affinity DataIC50:  171nMAssay Description:Inhibition of 0.5 nM [3H]- Bremazocine binding to Opioid receptor mu 1 of bovine striatum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50013766((S)-1-(11,15-dimethoxy-3-methyl-13-oxa-3-azahexacy...)
Affinity DataIC50:  323nMAssay Description:Inhibition of 0.5 nM [3H]- Bremazocine binding to Opioid receptor mu 1 of bovine striatum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50406412(CHEMBL2021333)
Affinity DataIC50:  434nMAssay Description:Inhibition of 0.5 nM [3H]- Bremazocine binding to Opioid receptor mu 1 of bovine striatum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50013760((R)-1-(11,15-dimethoxy-3-methyl-13-oxa-3-azahexacy...)
Affinity DataIC50:  1.16E+3nMAssay Description:Inhibition of 0.5 nM [3H]- Bremazocine binding to Opioid receptor mu 1 of bovine striatum membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed