Compile Data Set for Download or QSAR
maximum 50k data
Found 228 of ic50 for UniProtKB: P62937
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM172717(US9090657, 24)
Affinity DataIC50:  0.310nMAssay Description:The PPlase activity of recombinant CypA or D, produced by thrombin cleavage of GST-CypA or D, was determined by following the rate of hydrolysis of N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM172715(US9090657, DEBIO-025, 2)
Affinity DataIC50:  0.800nMAssay Description:The PPlase activity of recombinant CypA or D, produced by thrombin cleavage of GST-CypA or D, was determined by following the rate of hydrolysis of N...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50295470(1-(2-Chloro-6-fluorobenzoyl)-3-(9H-fluoren-9-yl)-u...)
Affinity DataIC50:  1.52nMAssay Description:Inhibition of peptidyl-prolyl isomerase activity of Cyclophilin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataIC50:  2nMAssay Description:Immunosuppressive activity was measured by inhibition of the IL-2 production in Jurkat cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50037809((R)-30-Ethyl-33-((E)-(1R,2R)-1-hydroxy-2-methyl-he...)
Affinity DataIC50:  2.30nMAssay Description:Compound was evaluated for in vitro binding affinity to cyclophilin A (CyP-A)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM172716(US9090657, Sanglifehrin A, 5)
Affinity DataIC50:  2.40nMAssay Description:The PPlase activity of recombinant CypA or D, produced by thrombin cleavage of GST-CypA or D, was determined by following the rate of hydrolysis of N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50295469(1-(2,6-Dichlorobenzoyl)-3-(9H-fluoren-9-yl)-urea |...)
Affinity DataIC50:  2.59nMAssay Description:Inhibition of peptidyl-prolyl isomerase activity of Cyclophilin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50323715(2-(((2R,5S,8S,11S,14S,17S,23S,26S,29S,32S)-17-ethy...)
Affinity DataIC50:  2.79nMAssay Description:Inhibition of PPIase activity of cyclophilin 18 by protease coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50136490(CHEMBL3038087 | Cyclosporin A analogue)
Affinity DataIC50:  3nMAssay Description:Immunosuppressive activity was measured by inhibition of the IL-2 production in Jurkat cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of PPIase activity of cyclophilin 18 by protease coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50323716(2-(((2R,5S,8S,11S,14S,17S,23S,26S,29S,32S)-17-ethy...)
Affinity DataIC50:  4.75nMAssay Description:Inhibition of PPIase activity of cyclophilin 18 by protease coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50356016(CHEMBL1911379)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of PPIase activity of human recombinant cyclophilin-A using succinyl-Ala-Ala-Pro-Phe-4-nitroanilide as substrate by protease coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50500613(CHEMBL3752642)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of Cyclophilin A peptidyl-prolyl cis-trans isomerase activity (unknown origin) using Succ-Ala-Leu-Pro-Phe-p-nitroaniline as substrate by I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataIC50:  7.20nMAssay Description:Inhibition of Cyclophilin A peptidyl-prolyl cis-trans isomerase activity (unknown origin) using Succ-Ala-Leu-Pro-Phe-p-nitroaniline as substrate by I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataIC50:  8.33nMAssay Description:Binding affinity to cyclophilin A by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataIC50:  9nMAssay Description:Compound was evaluated for in vitro binding affinity to cyclophilin A (CyP-A)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50330185(2-((2R,5S,8S,11S,14S,17S,23S,26S,29S,32S)-17-ethyl...)
Affinity DataIC50:  9.12nMAssay Description:Binding affinity to cyclophilin A by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataIC50:  9.30nMAssay Description:Inhibition of PPIase activity of human recombinant cyclophilin-A using succinyl-Ala-Ala-Pro-Phe-4-nitroanilide as substrate by protease coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50323721((3S,6S,9S,12R,15S,18S,21S,24S,27S,30S,33S)-27-(2-(...)
Affinity DataIC50:  9.48nMAssay Description:Binding affinity to cyclophilin A by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM172718(US11802108, Compound CSA | US9090657, Cyclosporine...)
Affinity DataIC50:  9.70nMAssay Description:The PPlase activity of recombinant CypA or D, produced by thrombin cleavage of GST-CypA or D, was determined by following the rate of hydrolysis of N...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataIC50:  10.3nMAssay Description:Inhibition of PPIase activity of Cyclophilin A by SpectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50500614(CHEMBL3754544)
Affinity DataIC50:  11nMAssay Description:Inhibition of Cyclophilin A peptidyl-prolyl cis-trans isomerase activity (unknown origin) using Succ-Ala-Leu-Pro-Phe-p-nitroaniline as substrate by I...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50330190((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-12-(4-amino...)
Affinity DataIC50:  11.1nMAssay Description:Binding affinity to cyclophilin A by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50295474(1-(2-Benzyloxybenzoyl)-3-(9H-fluoren-9-yl)-urea | ...)
Affinity DataIC50:  12.1nMAssay Description:Inhibition of peptidyl-prolyl isomerase activity of Cyclophilin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50613629(CHEMBL5268140)
Affinity DataIC50:  14nMAssay Description:Inhibition of CypA (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50330194((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-12-(4-(dime...)
Affinity DataIC50:  14nMAssay Description:Binding affinity to cyclophilin A by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50181474(1-(3-benzyloxy-pyridin-2-yl)-3-(4-nitro-phenyl)-ur...)
Affinity DataIC50:  14nMAssay Description:Inhibition of isomerase activity of Cyclophilin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50136484(CHEMBL2407581 | Cyclosporin A analogue)
Affinity DataIC50:  15nMAssay Description:Immunosuppressive activity was measured by inhibition of the IL-2 production in Jurkat cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50037808((S)-30-Ethyl-33-((E)-(1R,2R)-1-hydroxy-2-methyl-he...)
Affinity DataIC50:  16nMAssay Description:Compound was evaluated for in vitro binding affinity to cyclophilin A (CyP-A)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50136476(CHEMBL3038089 | Cyclosporin A analogue)
Affinity DataIC50:  19nMAssay Description:Immunosuppressive activity was measured by inhibition of the IL-2 production in Jurkat cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50136479(CHEMBL3038084 | Cyclosporin A analogue)
Affinity DataIC50:  19.5nMAssay Description:Immunosuppressive activity was measured by inhibition of the IL-2 production in Jurkat cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50136472(CHEMBL3038082 | [(40-OH) MeLeu]4-CsA derivatives)
Affinity DataIC50:  19.5nMAssay Description:Immunosuppressive activity was measured by inhibition of the IL-2 production in Jurkat cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50181489(4-[3-(3-benzyloxy-pyridin-2-yl)-ureido]-benzoic ac...)
Affinity DataIC50:  20nMAssay Description:Inhibition of isomerase activity of Cyclophilin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50330197((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-12-(3-(diet...)
Affinity DataIC50:  21.4nMAssay Description:Binding affinity to cyclophilin A by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50330184(CHEMBL1269582 | N-(4-((2R,5S,8S,11S,14S,17S,23S,26...)
Affinity DataIC50:  22.8nMAssay Description:Binding affinity to cyclophilin A by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50330191((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-12-((dimeth...)
Affinity DataIC50:  22.9nMAssay Description:Binding affinity to cyclophilin A by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataIC50:  23nMAssay Description:Inhibition of CypA (unknown origin) assessed as peptidyl-prolyl cis-trans isomerase activity using N-succinyl-Ala-Ala-Pro-Phe-p-nitroanilide as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50330186(3-((2R,5S,8S,11S,14S,17S,23S,26S,29S,32S)-17-ethyl...)
Affinity DataIC50:  23nMAssay Description:Binding affinity to cyclophilin A by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50136485(CHEMBL3038085 | Cyclosporin A analogue)
Affinity DataIC50:  24nMAssay Description:Immunosuppressive activity was measured by inhibition of the IL-2 production in Jurkat cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50330198((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-12-(4-(diet...)
Affinity DataIC50:  26.6nMAssay Description:Binding affinity to cyclophilin A by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50330183(CHEMBL1269581 | N-(3-((2R,5S,8S,11S,14S,17S,23S,26...)
Affinity DataIC50:  26.7nMAssay Description:Binding affinity to cyclophilin A by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataIC50:  27nMAssay Description:In vitro binding affinity of the compound against cyclophilin A by rotamase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50323712((R,S,S,S,S,S,R,R,S,S,S,S,E)-N,N'-(4,4'-((Z)-diazen...)
Affinity DataIC50:  30nMAssay Description:Inhibition of PPIase activity of cyclophilin 18 by protease coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50330182(CHEMBL1269580 | N-(2-((2R,5S,8S,11S,14S,17S,23S,26...)
Affinity DataIC50:  31.2nMAssay Description:Binding affinity to cyclophilin A by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50295455(1-(2,6-Dihydroxybenzoyl)-3-(9H-fluoren-9-yl)-urea ...)
Affinity DataIC50:  31.6nMAssay Description:Inhibition of peptidyl-prolyl isomerase activity of Cyclophilin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50295455(1-(2,6-Dihydroxybenzoyl)-3-(9H-fluoren-9-yl)-urea ...)
Affinity DataIC50:  32nMAssay Description:Inhibition of CypA (unknown origin) assessed as peptidyl-prolyl cis-trans isomerase activity using N-succinyl-Ala-Ala-Pro-Phe-p-nitroanilide as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50342826(CHEMBL1770807 | Trp-Gly-Pro)
Affinity DataIC50:  33.1nMAssay Description:Inhibition of PPIase activity of Cyclophilin A by SpectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50330193((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-12-(3-(dime...)
Affinity DataIC50:  35.2nMAssay Description:Binding affinity to cyclophilin A by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataIC50:  40.7nMAssay Description:Inhibition of peptidyl-prolyl isomerase activity of Cyclophilin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Neurovive Pharmaceutical

US Patent
LigandPNGBDBM50136483(CHEMBL3038083 | [(40-OH) MeLeu]4-CsA derivatives)
Affinity DataIC50:  43nMAssay Description:Immunosuppressive activity was measured by inhibition of the IL-2 production in Jurkat cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 228 total ) | Next | Last >>
Jump to: