Compile Data Set for Download or QSAR
maximum 50k data
Found 1747 of ic50 for UniProtKB: P18564
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50110227(3-{2-[4-(4-Methyl-pyridin-2-ylamino)-butyrylamino]...)
Affinity DataIC50:  0.0400nMAssay Description:Inhibition of integrin alphavbeta6 (unknown origin) by Merck binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50110227(3-{2-[4-(4-Methyl-pyridin-2-ylamino)-butyrylamino]...)
Affinity DataIC50:  0.0400nMAssay Description:Inhibition of fibronectin binding to recombinant human alphaV-beta6 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-6/beta-8(Homo sapiens (Human))
Scifluor Life Sciences

US Patent
LigandPNGBDBM297773(US10118929, Compound A1)
Affinity DataIC50:  0.130nMAssay Description:The optimized protocol was validated by employing reference compounds such as Cilengitide (+Vβ3/αVβ5−VN interaction) and CWHM12 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50110228(3-{2-[4-(4-Methyl-pyridin-2-ylamino)-butyrylamino]...)
Affinity DataIC50:  0.150nMAssay Description:Inhibition of fibronectin binding to recombinant human alphaV-beta6 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-6(Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279573((3S)-3-(3,5-dibromophenyl)-3-[[2-[[5-[(5-hydroxy-1...)
Affinity DataIC50:  0.200nMAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 g/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM MgCl2, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM279573((3S)-3-(3,5-dibromophenyl)-3-[[2-[[5-[(5-hydroxy-1...)
Affinity DataIC50:  0.200nMpH: 7.4 T: 2°CAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50530099(CHEMBL4441624)
Affinity DataIC50:  0.260nMAssay Description:Inhibition of LAP binding to human integrin alphavbeta6 receptor after 1 hr by solid-phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50530099(CHEMBL4441624)
Affinity DataIC50:  0.260nMAssay Description:Inhibition of LAP binding to human integrin alphavbeta6 receptor after 1 hr by solid-phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50565948(CHEMBL4780301)
Affinity DataIC50:  0.260nMAssay Description:Binding affinity to human integrin alphaVbeta6 incubated for 1 hr by ELISA based solid phase integrin binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM279561((3S)-3-(3-bromo-5-(trifluoromethyl)phenyl)-3-(2-(3...)
Affinity DataIC50:  0.300nMpH: 7.4 T: 2°CAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-6(Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279569((3S)-3-[3,5-bis(trifluoromethyl)phenyl)-3-(2-(3-hy...)
Affinity DataIC50:  0.300nMAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 g/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM MgCl2, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-6(Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279568((3S)-3-[3-bromo-5-(trifluoromethyl)phenyl]-3-[[2-[...)
Affinity DataIC50:  0.300nMAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 g/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM MgCl2, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-6(Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279566((3S)-3-[3-chloro-5-(trifluoromethyl)phenyl]3-[[2-[...)
Affinity DataIC50:  0.300nMAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 g/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM MgCl2, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-6(Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279561((3S)-3-(3-bromo-5-(trifluoromethyl)phenyl)-3-(2-(3...)
Affinity DataIC50:  0.300nMAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 g/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM MgCl2, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM279569((3S)-3-[3,5-bis(trifluoromethyl)phenyl)-3-(2-(3-hy...)
Affinity DataIC50:  0.300nMpH: 7.4 T: 2°CAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM279568((3S)-3-[3-bromo-5-(trifluoromethyl)phenyl]-3-[[2-[...)
Affinity DataIC50:  0.300nMpH: 7.4 T: 2°CAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM279566((3S)-3-[3-chloro-5-(trifluoromethyl)phenyl]3-[[2-[...)
Affinity DataIC50:  0.300nMpH: 7.4 T: 2°CAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-6(Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279572((3S)-3-[3-bromo-5-fluoro-phenyl)-3-(2-(3-hydroxy-5...)
Affinity DataIC50:  0.400nMAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 g/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM MgCl2, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-6(Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279567((3S)-3-(3-bromo-5-chloro-phenyl)-3-[[2-[[5-[(5-hyd...)
Affinity DataIC50:  0.400nMAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 g/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM MgCl2, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM279565((3S)-3-[3-bromo-5-chloro-phenyl)-3-(2-(3-hydroxy-5...)
Affinity DataIC50:  0.400nMpH: 7.4 T: 2°CAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-6(Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279565((3S)-3-[3-bromo-5-chloro-phenyl)-3-(2-(3-hydroxy-5...)
Affinity DataIC50:  0.400nMAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 g/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM MgCl2, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM279560((3S)-3-(3,5-dibromophenyl)-3-(2-(3-hydroxy-5-((5-h...)
Affinity DataIC50:  0.400nMpH: 7.4 T: 2°CAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM279563((3S)-3-[3-bromo-5-(difluoromethyl)phenyl)-3-(2-(3-...)
Affinity DataIC50:  0.400nMpH: 7.4 T: 2°CAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM279562((3S)-3-[3-chloro-5-(difluoromethyl)phenyl)-3-(2-(3...)
Affinity DataIC50:  0.400nMpH: 7.4 T: 2°CAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM279567((3S)-3-(3-bromo-5-chloro-phenyl)-3-[[2-[[5-[(5-hyd...)
Affinity DataIC50:  0.400nMpH: 7.4 T: 2°CAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-6(Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279560((3S)-3-(3,5-dibromophenyl)-3-(2-(3-hydroxy-5-((5-h...)
Affinity DataIC50:  0.400nMAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 g/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM MgCl2, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM279572((3S)-3-[3-bromo-5-fluoro-phenyl)-3-(2-(3-hydroxy-5...)
Affinity DataIC50:  0.400nMpH: 7.4 T: 2°CAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-6(Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279562((3S)-3-[3-chloro-5-(difluoromethyl)phenyl)-3-(2-(3...)
Affinity DataIC50:  0.400nMAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 g/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM MgCl2, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-6(Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279563((3S)-3-[3-bromo-5-(difluoromethyl)phenyl)-3-(2-(3-...)
Affinity DataIC50:  0.400nMAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 g/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM MgCl2, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50110236(3-(3,5-Dichloro-phenyl)-3-{2-[5-(4-methyl-pyridin-...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of fibronectin binding to recombinant human alphaV-beta6 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM279570((3S)-3-[3-bromo-5-methyl-phenyl)-3-(2-(3-hydroxy-5...)
Affinity DataIC50:  0.5nMpH: 7.4 T: 2°CAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-6(Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279564((3S)-3-[3-chloro-5-(trifluoromethyl)phenyl)-3-(2-(...)
Affinity DataIC50:  0.5nMAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 g/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM MgCl2, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM279575((3S)-3-[3-chloro-5-(trifluoromethoxy)phenyl)-3-(2-...)
Affinity DataIC50:  0.5nMpH: 7.4 T: 2°CAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM279564((3S)-3-[3-chloro-5-(trifluoromethyl)phenyl)-3-(2-(...)
Affinity DataIC50:  0.5nMpH: 7.4 T: 2°CAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-6(Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279575((3S)-3-[3-chloro-5-(trifluoromethoxy)phenyl)-3-(2-...)
Affinity DataIC50:  0.5nMAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 g/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM MgCl2, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-6(Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279570((3S)-3-[3-bromo-5-methyl-phenyl)-3-(2-(3-hydroxy-5...)
Affinity DataIC50:  0.5nMAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 g/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM MgCl2, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM606867(US11685738, Compound A3)
Affinity DataIC50:  0.570nMAssay Description:The full reaction (Integrin-Ligand Interaction) was optimized as above. Integrin coupled beads were taken for the experiment. 2 μL of 10 nM/20 n...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM279571((3S)-3-[3-chloro-5-methyl-phenyl)-3-(2-(3-hydroxy-...)
Affinity DataIC50:  0.600nMpH: 7.4 T: 2°CAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-6(Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279571((3S)-3-[3-chloro-5-methyl-phenyl)-3-(2-(3-hydroxy-...)
Affinity DataIC50:  0.600nMAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 g/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM MgCl2, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50110232(3-Biphenyl-4-yl-3-{2-[5-(pyridin-2-ylamino)-pentan...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of fibronectin binding to recombinant human alphaV-beta6 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50110232(3-Biphenyl-4-yl-3-{2-[5-(pyridin-2-ylamino)-pentan...)
Affinity DataIC50:  0.600nMAssay Description:Antagonist activity at alphavbeta6 integrin receptor (unknown origin) by cell-free ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM279574((3S)-3-[3,5-dichloro-phenyl)-3-(2-(3-hydroxy-5-((5...)
Affinity DataIC50:  0.600nMpH: 7.4 T: 2°CAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-6(Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279574((3S)-3-[3,5-dichloro-phenyl)-3-(2-(3-hydroxy-5-((5...)
Affinity DataIC50:  0.600nMAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 g/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM MgCl2, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50530110(CHEMBL4575627)
Affinity DataIC50:  0.670nMAssay Description:Inhibition of LAP binding to human integrin alphavbeta6 receptor after 1 hr by solid-phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50530110(CHEMBL4575627)
Affinity DataIC50:  0.670nMAssay Description:Inhibition of LAP binding to human integrin alphavbeta6 receptor after 1 hr by solid-phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM279576((3S)-3-(3-bromo-5-(trifluoromethoxy)phenyl)-3-(2-(...)
Affinity DataIC50:  0.700nMpH: 7.4 T: 2°CAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-6(Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279576((3S)-3-(3-bromo-5-(trifluoromethoxy)phenyl)-3-(2-(...)
Affinity DataIC50:  0.700nMAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 g/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM MgCl2, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-6(Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM432097(US10577330, Comparison Compound C6)
Affinity DataIC50:  1nMAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 g/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM MgCl2, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-6(Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM432094(US10577330, Comparison Compound C3)
Affinity DataIC50:  1nMAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 g/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM MgCl2, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL
LigandPNGBDBM50464106(CHEMBL4237498)
Affinity DataIC50:  1nMAssay Description:Antagonist activity at human integrin alphaVbeta6 expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP after 30 mins by BC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 1747 total ) | Next | Last >>
Jump to: