Compile Data Set for Download or QSAR
maximum 50k data
Found 16 of ki for UniProtKB: P48450
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50003025(1-((4aS,5S,6S,8aS)-6-Hydroxy-5,8a-dimethyl-octahyd...)
Affinity DataKi:  28nMAssay Description:Inhibitory concentration of the compound against purified rat liver Oxidosqualene cyclase (OSC)More data for this Ligand-Target Pair
In DepthDetails Article
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50055641(2,2-dimethyl-3-((3E,7E,11E)-3,7,12-trimethyl-14-(6...)
Affinity DataKi:  37nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50055642(2,2-Dimethyl-3-[(3E,7E,11E)-3,7,12-trimethyl-15-(4...)
Affinity DataKi:  180nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50051375((6S,8aS)-5,5,8a-Trimethyl-2-((E)-1,5,9-trimethyl-d...)
Affinity DataKi:  300nMAssay Description:Binding affinity towards competitive inhibition against rat microsomal Oxidosqualene-lanosterol cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50051375((6S,8aS)-5,5,8a-Trimethyl-2-((E)-1,5,9-trimethyl-d...)
Affinity DataKi:  400nMAssay Description:Binding affinity towards noncompetetive inhibition against rat microsomal Oxidosqualene-lanosterol cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50055643(2,2-Dimethyl-3-[(E)-3-methyl-7-((3E,7E)-4,8,12-tri...)
Affinity DataKi:  500nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from pig liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50055642(2,2-Dimethyl-3-[(3E,7E,11E)-3,7,12-trimethyl-15-(4...)
Affinity DataKi:  1.40E+3nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from pig liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50055641(2,2-dimethyl-3-((3E,7E,11E)-3,7,12-trimethyl-14-(6...)
Affinity DataKi:  1.50E+3nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from pig liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50055644(2-Methyl-3-((7E,11E,15Z)-3,7,12,20-tetramethyl-16-...)
Affinity DataKi:  2.50E+3nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290988(2,2-Dimethyl-3-(3,7,12,20-tetramethyl-16-vinyl-hen...)
Affinity DataKi:  2.50E+3nMAssay Description:Compound was evaluated for the binding affinity against rat liver oxidosqualene cyclase (OSC)More data for this Ligand-Target Pair
In DepthDetails Article
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50055644(2-Methyl-3-((7E,11E,15Z)-3,7,12,20-tetramethyl-16-...)
Affinity DataKi:  4.40E+3nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from pig liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50055640(3-[(3E,7E)-11-((E)-4,8-Dimethyl-nona-3,7-dienylsul...)
Affinity DataKi:  4.50E+3nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from pig liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290991(2,2-Dimethyl-3-(3,7,12,20-tetramethyl-16-vinyl-hen...)
Affinity DataKi:  4.50E+3nMAssay Description:Compound was evaluated for the binding affinity against rat liver oxidosqualene cyclase (OSC)More data for this Ligand-Target Pair
In DepthDetails Article
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290992(3-[16-(2,2-Difluoro-vinyl)-3,7,12,20-tetramethyl-h...)
Affinity DataKi:  1.02E+4nMAssay Description:Concentration that cause 50 percent inhibition of binding of [14C]-labeled (3S)-oxidosqualene to isolated rat liver oxidosqualene cyclase (OSC) was d...More data for this Ligand-Target Pair
In DepthDetails Article
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50290989(3-[16-(2,2-Difluoro-vinyl)-3,7,12,20-tetramethyl-h...)
Affinity DataKi:  1.20E+4nMAssay Description:Compound was evaluated for the binding affinity against rat liver oxidosqualene cyclase (OSC)More data for this Ligand-Target Pair
In DepthDetails Article
TargetLanosterol synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50055645((6E,10E,14E)-2,6,10,15,19-Pentamethyl-21-(3-methyl...)
Affinity DataKi:  6.00E+4nMAssay Description:Inhibition constant against rat liver Oxidosqualene-lanosterol cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed