Compile Data Set for Download or QSAR
maximum 50k data
Found 86 of ic50 for UniProtKB: P06756
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50235980(2-((2S,5R,8S,11S)-5-benzyl-11-(3-guanidinopropyl)-...)
Affinity DataIC50:  0.130nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta5 receptor in human placenta by microplate scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50276748(CHEMBL460012 | [(1R,3S,9S,11S,14R)-9-(3-Guanidino-...)
Affinity DataIC50:  0.900nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta5 receptor in human placenta by microplate scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50277112(3-[1-Oxo-6-(1,2,3,4-tetrahydro-benzo[4,5]imidazo[1...)
Affinity DataIC50:  1nMAssay Description:Binding affinity to human integrin alphavbeta3 receptor by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50277111(3-Benzo[1,3]dioxol-5-yl-3-[1-oxo-6-(1,2,3,4-tetrah...)
Affinity DataIC50:  2nMAssay Description:Binding affinity to human integrin alphavbeta3 receptor by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50277112(3-[1-Oxo-6-(1,2,3,4-tetrahydro-benzo[4,5]imidazo[1...)
Affinity DataIC50:  5nMAssay Description:Binding affinity to human integrin alphavbeta5 receptor by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50276748(CHEMBL460012 | [(1R,3S,9S,11S,14R)-9-(3-Guanidino-...)
Affinity DataIC50:  5.64nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta3 receptor in human placenta by microplate scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50277098(3-[1-Oxo-6-(1,2,3,4-tetrahydro-benzo[4,5]imidazo[1...)
Affinity DataIC50:  7nMAssay Description:Binding affinity to human integrin alphavbeta3 receptor by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50296598((R)-2-(2,4-dichlorophenylsulfonamido)-3-(thiophene...)
Affinity DataIC50:  8nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50265535(2-((2R,8R,11R,14S)-11-((5R,8S,11R,17R,20S,23R,26S)...)
Affinity DataIC50:  10.8nMAssay Description:Displacement of [125I]c(RGDyK) form integrin alphaVbeta3 receptor in human U87MG cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50296610((R)-3-(1-methyl-1H-pyrazole-5-carboxamido)-2-(2,4,...)
Affinity DataIC50:  11nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50265534(2-((2R,8R,11R,14S)-11-(4-aminobutyl)-8-(3-guanidin...)
Affinity DataIC50:  11.2nMAssay Description:Displacement of [125I]c(RGDyK) form integrin alphaVbeta3 receptor in human U87MG cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50265536(2-((2R,8R,11R,14S)-11-((5R,8S,11R,17R,20S,23R,26S)...)
Affinity DataIC50:  13.8nMAssay Description:Displacement of [125I]c(RGDyK) form integrin alphaVbeta3 receptor in human U87MG cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50277111(3-Benzo[1,3]dioxol-5-yl-3-[1-oxo-6-(1,2,3,4-tetrah...)
Affinity DataIC50:  14nMAssay Description:Binding affinity to human integrin alphavbeta5 receptor by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50276746(CHEMBL452724 | c[RGDf-(3S)-Carboxymorpholine])
Affinity DataIC50:  15.1nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta5 receptor in human placenta by microplate scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50235980(2-((2S,5R,8S,11S)-5-benzyl-11-(3-guanidinopropyl)-...)
Affinity DataIC50:  18.9nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta3 receptor in human placenta by microplate scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50296635((R)-2-(2,3-dichlorophenylsulfonamido)-3-(thiophene...)
Affinity DataIC50:  19nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50276747(CHEMBL443362 | c[RGDf-(3R)-Carboxymorpholine])
Affinity DataIC50:  21nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta5 receptor in human placenta by microplate scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50296597((R)-3-(thiophene-3-carboxamido)-2-(2,4,6-trichloro...)
Affinity DataIC50:  24nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50296603((R)-3-benzamido-2-(2-iodophenylsulfonamido)propano...)
Affinity DataIC50:  25nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50296611((R)-3-(furan-3-carboxamido)-2-(2,4,6-trimethylphen...)
Affinity DataIC50:  32nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50276747(CHEMBL443362 | c[RGDf-(3R)-Carboxymorpholine])
Affinity DataIC50:  32.6nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta3 receptor in human placenta by microplate scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50277096(3-(6-(2-amino-1-methyl-1H-benzo[d]imidazol-4-yloxy...)
Affinity DataIC50:  39nMAssay Description:Binding affinity to human integrin alphavbeta3 receptor by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50296609((R)-3-(2-methyloxazole-4-carboxamido)-2-(2,4,6-tri...)
Affinity DataIC50:  41nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50296612((R)-3-(thiophene-3-carboxamido)-2-(2,4,6-trimethyl...)
Affinity DataIC50:  44nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50296600((R)-3-benzamido-2-(2,3-dichlorophenylsulfonamido)p...)
Affinity DataIC50:  62nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50296607((R)-3-(pyrimidine-5-carboxamido)-2-(2,4,6-trimethy...)
Affinity DataIC50:  63nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50265536(2-((2R,8R,11R,14S)-11-((5R,8S,11R,17R,20S,23R,26S)...)
Affinity DataIC50:  73.3nMAssay Description:Displacement of [125I][Tyr4]BBN form integrin alphaVbeta3 receptor in human PC3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50296632((R)-3-(2-methoxybenzamido)-2-(2,4,6-trimethylpheny...)
Affinity DataIC50:  78nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50265537((S)-N1-((5R,8S,11R,17R,20S,23R)-11-((1H-imidazol-4...)
Affinity DataIC50:  79.0nMAssay Description:Displacement of [125I][Tyr4]BBN form integrin alphaVbeta3 receptor in human PC3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50296608((R)-3-(nicotinamido)-2-(2,4,6-trimethylphenylsulfo...)
Affinity DataIC50:  81nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50265535(2-((2R,8R,11R,14S)-11-((5R,8S,11R,17R,20S,23R,26S)...)
Affinity DataIC50:  85.5nMAssay Description:Displacement of [125I][Tyr4]BBN form integrin alphaVbeta3 receptor in human PC3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50296596((R)-2-(3-cyanophenylsulfonamido)-3-(furan-3-carbox...)
Affinity DataIC50:  98nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50296599((R)-3-benzamido-2-(2,6-dichlorophenylsulfonamido)p...)
Affinity DataIC50:  118nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50296623((R)-3-benzamido-2-(2,4,6-trimethylphenylsulfonamid...)
Affinity DataIC50:  120nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50276746(CHEMBL452724 | c[RGDf-(3S)-Carboxymorpholine])
Affinity DataIC50:  157nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta3 receptor in human placenta by microplate scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50277095(3-(5-(2-amino-1-methyl-1H-benzo[d]imidazol-4-yloxy...)
Affinity DataIC50:  180nMAssay Description:Binding affinity to human integrin alphavbeta3 receptor by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50296595((R)-3-(furan-3-carboxamido)-2-(3-methoxyphenylsulf...)
Affinity DataIC50:  208nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50277075(3-(4-(2-amino-1-methyl-1H-benzo[d]imidazol-4-yloxy...)
Affinity DataIC50:  230nMAssay Description:Binding affinity to human integrin alphavbeta3 receptor by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50296604((R)-3-benzamido-2-(2-chlorophenylsulfonamido)propa...)
Affinity DataIC50:  260nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50296633((R)-3-(furan-3-carboxamido)-2-(2-methylphenylsulfo...)
Affinity DataIC50:  260nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50296606((R)-3-(isonicotinamido)-2-(2,4,6-trimethylphenylsu...)
Affinity DataIC50:  301nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50277098(3-[1-Oxo-6-(1,2,3,4-tetrahydro-benzo[4,5]imidazo[1...)
Affinity DataIC50:  310nMAssay Description:Binding affinity to human integrin alphavbeta5 receptor by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50296605((R)-3-benzamido-2-(2-methylphenylsulfonamido)propa...)
Affinity DataIC50:  320nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50277097(3-(7-(2-amino-1-methyl-1H-benzo[d]imidazol-4-yloxy...)
Affinity DataIC50:  370nMAssay Description:Binding affinity to human integrin alphavbeta3 receptor by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50277096(3-(6-(2-amino-1-methyl-1H-benzo[d]imidazol-4-yloxy...)
Affinity DataIC50:  600nMAssay Description:Binding affinity to human integrin alphavbeta5 receptor by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50296634((R)-3-(furan-3-carboxamido)-2-(2-methoxyphenylsulf...)
Affinity DataIC50:  700nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50296601((R)-3-benzamido-2-(2-methoxyphenylsulfonamido)prop...)
Affinity DataIC50:  729nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50296594((R)-3-(furan-3-carboxamido)-2-(pyridine-3-sulfonam...)
Affinity DataIC50:  793nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50296629((R)-3-acetamido-2-(2,4,6-trimethylphenylsulfonamid...)
Affinity DataIC50:  800nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50296631((R)-3-(1-oxoisoindolin-2-yl)-2-(2,4,6-trimethylphe...)
Affinity DataIC50:  975nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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