Affinity DataIC50: 0.480nMAssay Description:Inhibition of DENV NS2B/NS3 proMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of DENV NS2B-NS3 protease assessed as fluorescence emission using benzoyl-Nle-Lys-Arg-Arg-AMC as substrate preincubated with enzyme for 60...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of DENV NS2B-NS3 protease assessed as fluorescence emission using benzoyl-Nle-Lys-Arg-Arg-AMC as substrate preincubated with enzyme for 60...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of DENV NS2B-NS3 protease assessed as fluorescence emission using benzoyl-Nle-Lys-Arg-Arg-AMC as substrate preincubated with enzyme for 60...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of DENV2 NS2B-NS3 protease using Boc-Gly-Arg-7-amino-4-methylcoumarin as substrate preincubated for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of DENV2 NS2B-NS3 protease using Boc-Gly-Arg-7-amino-4-methylcoumarin as substrate preincubated for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Inhibition of DENV2 NS2B-NS3 protease using Boc-Gly-Arg-7-amino-4-methylcoumarin as substrate preincubated for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
Affinity DataIC50: 74nMAssay Description:Inhibition of DENV NS2B-NS3 protease assessed as fluorescence emission using benzoyl-Nle-Lys-Arg-Arg-AMC as substrate preincubated with enzyme for 60...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of Dengue Virus 4 recombinant NS2B-NS3 protease expressed in Escherichia coli using Bz-Nle-Arg-Arg-AMC as substrate incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of Dengue Virus 2 recombinant NS2B-NS3 protease expressed in Escherichia coli using Bz-Nle-Arg-Arg-AMC as substrate incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of Dengue Virus 1 recombinant NS2B-NS3 protease expressed in Escherichia coli using Bz-Nle-Arg-Arg-AMC as substrate incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of Dengue Virus 3 recombinant NS2B-NS3 protease expressed in Escherichia coli using Bz-Nle-Arg-Arg-AMC as substrate incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of 6-His tagged-G4SG4 fused DENV2 NS2B (1394 to 1440 residues) -NS3 (1476 to 1660 residue) expressed in Escherichia coli BL21 (DE3) using ...More data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition Dengue serotype-2 NS3B/NS3 protease using 7-amino-4-methylcoumarin as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition Dengue serotype-2 NS3B/NS3 protease using 7-amino-4-methylcoumarin as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of Dengue virus 2 NS2B-NS3 protease using Abz-Nle-Lys-Arg-Arg-Ser-Tyr(3-NO2)-NH2 as substrate preincubated with enzyme for 15 mins followe...More data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of DENV-2 NS2B/NS3 protease expressed in Escherichia coli XL1 using Boc-GRR-MCA as substrate preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of Dengue virus serotype 2 NS2B-NS3 protease preincubated with protein for 15 mins followed by Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Tyr substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of Dengue virus 2 NS2B-NS3 protease using Abz-Nle-Lys-Arg-Arg-Ser-Tyr(3-NO2)-NH2 as substrate preincubated with enzyme for 15 mins followe...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of Dengue virus 2 NS2B-NS3 protease using Abz-Nle-Lys-Arg-Arg-Ser-Tyr(3-NO2)-NH2 as substrate preincubated with enzyme for 15 mins followe...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of Dengue virus 2 NS3 helicase incubated for 2 mins followed by ATP additionMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of DENV2 NS2B-NS3 protease using fluorophore-tagged Bz-nKRR-AMC as substrate preincubated for 30 mins followed by substrate addition measu...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of DENV NS2B-NS3 protease assessed as fluorescence emission using benzoyl-Nle-Lys-Arg-Arg-AMC as substrate preincubated with enzyme for 60...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of DENV2 NS2B-NS3 protease expressed in Escherichia coli assessed as fluorescence emission using Bz-nKRR-AMC as substrate by microplate re...More data for this Ligand-Target Pair
Affinity DataIC50: 540nMAssay Description:Inhibition of Dengue virus serotype 2 NS2B-NS3 protease expressed in Escherichia coli BL21 lambda (DE3) cells using Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Ty...More data for this Ligand-Target Pair
Affinity DataIC50: 590nMAssay Description:Inhibition Dengue serotype-2 NS3B/NS3 protease using 7-amino-4-methylcoumarin as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of Dengue virus serotype 2 NS2B-NS3 protease preincubated with protein for 15 mins followed by Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Tyr substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 640nMAssay Description:Inhibition of Dengue Virus 3 recombinant NS2B-NS3 protease expressed in Escherichia coli using Bz-Nle-Arg-Arg-AMC as substrate incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 640nMAssay Description:Inhibition of Dengue Virus 4 recombinant NS2B-NS3 protease expressed in Escherichia coli using Bz-Nle-Arg-Arg-AMC as substrate incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 640nMAssay Description:Inhibition of DENV2 NS2B-NS3 serine protease expressed using Benzoyl-Nle-Lys-Arg-Arg-AMC as substrate measured preincubated for 3 mins followed by su...More data for this Ligand-Target Pair
Affinity DataIC50: 640nMAssay Description:Inhibition Dengue serotype-2 NS3B/NS3 protease using 7-amino-4-methylcoumarin as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 640nMAssay Description:Inhibition of Dengue Virus 1 recombinant NS2B-NS3 protease expressed in Escherichia coli using Bz-Nle-Arg-Arg-AMC as substrate incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 640nMAssay Description:Inhibition of Dengue Virus 2 recombinant NS2B-NS3 protease expressed in Escherichia coli using Bz-Nle-Arg-Arg-AMC as substrate incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 680nMAssay Description:Inhibition of Dengue virus serotype 2 NS2B-NS3 protease expressed in Escherichia coli BL21 lambda (DE3) cells using Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Ty...More data for this Ligand-Target Pair
Affinity DataIC50: 690nMAssay Description:Inhibition of DENV2 NS2B-NS3 protease expressed in Escherichia coli BL21(DE3) using Boc-Gly-Arg-Arg-AMC as substrate by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 730nMAssay Description:Inhibition Dengue serotype-2 NS3B/NS3 protease using 7-amino-4-methylcoumarin as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 860nMAssay Description:Inhibition Dengue serotype-2 NS3B/NS3 protease using 7-amino-4-methylcoumarin as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 980nMAssay Description:Inhibition Dengue serotype-2 NS3B/NS3 protease using 7-amino-4-methylcoumarin as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 990nMAssay Description:Inhibition of DENV3 NS2B-NS3 protease using PhAc-Lys-Arg-Arg-AMC as substrate incubated for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 990nMAssay Description:Inhibition of Dengue virus 3 NS2B-NS3 protease expressed in Escherichia coli BL21(DE3) using PhAc-Lys-Arg-Arg-AMC as substrate after 10 mins by fluor...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Dengue virus serotype 2 NS2B-NS3 protease expressed in Escherichia coli BL21 lambda (DE3) cells using Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Ty...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Dengue virus serotype 2 NS2B-NS3 protease preincubated with protein for 15 mins followed by Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Tyr substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of RNA unwinding activity of thioredoxin/His6 tagged Dengue virus 2 TSV01 NS3 helicase (171 to 618 residues) expressed in Escherichia coli...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Dengue virus 2 NS2B (50 to 95 residues)/NS3 (1 to 182 residues) protease expressed in Escherichia coli BL21 using Bz-Nle-Lys-Lys-Arg-AM...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Dengue virus serotype 2 NS2B-NS3 protease preincubated with protein for 15 mins followed by Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Tyr substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of C-terminal His6-tagged linked Dengue virus serotype 2 NS2B-NS3 protease domain expressed in Escherichia coli Bl21(DE3) preincubated for...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Dengue virus 2 NS2B-NS3 protease using Abz-Nle-Lys-Arg-Arg-Ser-Tyr(3-NO2)-NH2 as substrate preincubated with enzyme for 15 mins followe...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of Dengue virus serotype 2 NS2B-NS3 protease expressed in Escherichia coli BL21 lambda (DE3) cells using Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Ty...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of DENV2 NS2B-NS3 protease expressed in Escherichia coli Rosetta2(DE3) using Abz-RRRRSAG-nTyr as substrate preincubated with enzyme for 30...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of Dengue virus 2 NS2B (48 to 95 residues)-NS3 (1 to 185 residues) expressed in Escherichia coli BL21 Rosetta (DE3) incubated for 30 mins ...More data for this Ligand-Target Pair