Compile Data Set for Download or QSAR
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Found 52 of ec50 for UniProtKB: P58681
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50543465(CHEMBL4636498)
Affinity DataEC50:  2.40nMAssay Description:Invivo antagonist activity at TLR7 in po dosed C57BL/6 mouse assessed as reduction of gardiquimod-induced IL-6 production pretreated for 30 mins foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50425234(CHEMBL2315158)
Affinity DataEC50:  4.60nMAssay Description:Agonist activity at mouse TLR7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539350(CHEMBL4635551)
Affinity DataEC50:  27nMAssay Description:Agonist activity at TLR7 in mouse BMDC cells assessed as immunostimulatory activity by measuring increase in IL6 secretion incubated for 18 hrs by EL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539351(CHEMBL4635169)
Affinity DataEC50:  40nMAssay Description:Agonist activity at TLR7 in mouse BMDC cells assessed as immunostimulatory activity by measuring increase in IL6 secretion incubated for 18 hrs by EL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539351(CHEMBL4635169)
Affinity DataEC50:  40nMAssay Description:Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 18 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539352(CHEMBL4636482)
Affinity DataEC50:  56nMAssay Description:Agonist activity at TLR7 in mouse BMDC cells assessed as immunostimulatory activity by measuring increase in IL6 secretion incubated for 18 hrs by EL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539350(CHEMBL4635551)
Affinity DataEC50:  57nMAssay Description:Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 18 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539347(CHEMBL4639831)
Affinity DataEC50:  71nMAssay Description:Agonist activity at TLR7 in mouse BMDC cells assessed as immunostimulatory activity by measuring increase in IL6 secretion incubated for 18 hrs by EL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539346(CHEMBL4641702)
Affinity DataEC50:  80nMAssay Description:Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 18 ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539345(CHEMBL4645661)
Affinity DataEC50:  99nMAssay Description:Agonist activity at TLR7 in mouse BMDC cells assessed as immunostimulatory activity by measuring increase in IL6 secretion incubated for 18 hrs by EL...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539352(CHEMBL4636482)
Affinity DataEC50:  107nMAssay Description:Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 18 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539349(CHEMBL4636020)
Affinity DataEC50:  108nMAssay Description:Agonist activity at TLR7 in mouse BMDC cells assessed as immunostimulatory activity by measuring increase in IL6 secretion incubated for 18 hrs by EL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539346(CHEMBL4641702)
Affinity DataEC50:  110nMAssay Description:Agonist activity at TLR7 in mouse BMDC cells assessed as immunostimulatory activity by measuring increase in IL6 secretion incubated for 18 hrs by EL...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539347(CHEMBL4639831)
Affinity DataEC50:  128nMAssay Description:Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 18 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50189287(CHEMBL3827413 | US9597326, Compound 11)
Affinity DataEC50:  130nMAssay Description:Agonist activity at TLR7 in Balb/c mouse splenocytes assessed as induction of IL-6 secretion in supernatant after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539349(CHEMBL4636020)
Affinity DataEC50:  132nMAssay Description:Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 18 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539345(CHEMBL4645661)
Affinity DataEC50:  136nMAssay Description:Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 18 ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539341(CHEMBL4632609)
Affinity DataEC50:  153nMAssay Description:Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 18 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539348(CHEMBL4647802)
Affinity DataEC50:  153nMAssay Description:Agonist activity at TLR7 in mouse BMDC cells assessed as immunostimulatory activity by measuring increase in IL6 secretion incubated for 18 hrs by EL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539350(CHEMBL4635551)
Affinity DataEC50:  186nMAssay Description:Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 6 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50189181(CHEMBL3828229 | US9597326, Compound 21)
Affinity DataEC50:  190nMAssay Description:Agonist activity at TLR7 in Balb/c mouse splenocytes assessed as induction of IL-6 secretion in supernatant after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539342(CHEMBL4641619)
Affinity DataEC50:  198nMAssay Description:Agonist activity at TLR7 in mouse BMDC cells assessed as immunostimulatory activity by measuring increase in IL6 secretion incubated for 18 hrs by EL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539341(CHEMBL4632609)
Affinity DataEC50:  210nMAssay Description:Agonist activity at TLR7 in mouse BMDC cells assessed as immunostimulatory activity by measuring increase in IL6 secretion incubated for 18 hrs by EL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539342(CHEMBL4641619)
Affinity DataEC50:  230nMAssay Description:Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 18 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539340(CHEMBL4640564)
Affinity DataEC50:  234nMAssay Description:Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 18 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539340(CHEMBL4640564)
Affinity DataEC50:  239nMAssay Description:Agonist activity at TLR7 in mouse BMDC cells assessed as immunostimulatory activity by measuring increase in IL6 secretion incubated for 18 hrs by EL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539339(CHEMBL4637769)
Affinity DataEC50:  252nMAssay Description:Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 18 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539344(CHEMBL4647035)
Affinity DataEC50:  252nMAssay Description:Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 18 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539343(CHEMBL4639099)
Affinity DataEC50:  258nMAssay Description:Agonist activity at TLR7 in mouse BMDC cells assessed as immunostimulatory activity by measuring increase in IL6 secretion incubated for 18 hrs by EL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539345(CHEMBL4645661)
Affinity DataEC50:  277nMAssay Description:Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 6 h...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539348(CHEMBL4647802)
Affinity DataEC50:  287nMAssay Description:Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 18 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539344(CHEMBL4647035)
Affinity DataEC50:  303nMAssay Description:Agonist activity at TLR7 in mouse BMDC cells assessed as immunostimulatory activity by measuring increase in IL6 secretion incubated for 18 hrs by EL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50189282(CHEMBL3828331 | US9597326, Compound 15)
Affinity DataEC50:  310nMAssay Description:Agonist activity at TLR7 in Balb/c mouse splenocytes assessed as induction of IL-6 secretion in supernatant after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539343(CHEMBL4639099)
Affinity DataEC50:  316nMAssay Description:Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 18 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539339(CHEMBL4637769)
Affinity DataEC50:  434nMAssay Description:Agonist activity at TLR7 in mouse BMDC cells assessed as immunostimulatory activity by measuring increase in IL6 secretion incubated for 18 hrs by EL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539342(CHEMBL4641619)
Affinity DataEC50:  490nMAssay Description:Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 6 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50189288(CHEMBL3828701 | US9597326, Compound 12)
Affinity DataEC50:  570nMAssay Description:Agonist activity at TLR7 in Balb/c mouse splenocytes assessed as induction of IL-6 secretion in supernatant after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539345(CHEMBL4645661)
Affinity DataEC50:  585nMAssay Description:Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion preincubated with...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50189283(CHEMBL3828542 | US9597326, Compound 6)
Affinity DataEC50:  810nMAssay Description:Agonist activity at TLR7 in Balb/c mouse splenocytes assessed as induction of IL-6 secretion in supernatant after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539342(CHEMBL4641619)
Affinity DataEC50:  909nMAssay Description:Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion preincubated with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539350(CHEMBL4635551)
Affinity DataEC50:  1.06E+3nMAssay Description:Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion preincubated with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50189286(CHEMBL3827244 | US9597326, Compound 1)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at TLR7 in Balb/c mouse splenocytes assessed as induction of IL-6 secretion in supernatant after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50189180(CHEMBL3827257 | US9597326, Compound 18)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at TLR7 in Balb/c mouse splenocytes assessed as induction of IL-6 secretion in supernatant after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539339(CHEMBL4637769)
Affinity DataEC50:  2.11E+3nMAssay Description:Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion preincubated with...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50539339(CHEMBL4637769)
Affinity DataEC50:  2.15E+3nMAssay Description:Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 6 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50189281(CHEMBL3827669 | US9597326, Compound 16)
Affinity DataEC50:  2.40E+3nMAssay Description:Agonist activity at TLR7 in Balb/c mouse splenocytes assessed as induction of IL-6 secretion in supernatant after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50189289(CHEMBL3828519 | US9597326, Compound 10)
Affinity DataEC50:  2.50E+3nMAssay Description:Agonist activity at TLR7 in Balb/c mouse splenocytes assessed as induction of IL-6 secretion in supernatant after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50189285(CHEMBL3828296 | US9597326, Compound 5)
Affinity DataEC50:  3.20E+3nMAssay Description:Agonist activity at TLR7 in Balb/c mouse splenocytes assessed as induction of IL-6 secretion in supernatant after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50189290(CHEMBL3828149 | US9597326, Compound 9)
Affinity DataEC50:  3.40E+3nMAssay Description:Agonist activity at TLR7 in Balb/c mouse splenocytes assessed as induction of IL-6 secretion in supernatant after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Princ

Curated by ChEMBL
LigandPNGBDBM50189284(CHEMBL3828386 | US9597326, Compound 27)
Affinity DataEC50:  3.60E+3nMAssay Description:Agonist activity at TLR7 in Balb/c mouse splenocytes assessed as induction of IL-6 secretion in supernatant after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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