Compile Data Set for Download or QSAR
maximum 50k data
Found 17 of ic50 for UniProtKB: P58681
TargetToll-like receptor 7(Mus musculus)
Biocon Bristol Myers Squibb Research Center (Bbrc)

Curated by ChEMBL
LigandPNGBDBM21958(2-(2,6-dimethylpyridin-4-yl)-3-isopropyl-5-(piperi...)
Affinity DataIC50:  0.300nMAssay Description:Antagonist activity at gardiquimod stimulated TRL7 in mouse whole blood assessed as inhibition of IL-6 production by ELISA analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetToll-like receptor 7(Mus musculus)
Biocon Bristol Myers Squibb Research Center (Bbrc)

Curated by ChEMBL
LigandPNGBDBM50586262(CHEMBL5091113)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at mouse TLR7 expressed in human whole blood assessed as inhibition of ssRNA stimulated IFNalpha level preincubated for 30 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Biocon Bristol Myers Squibb Research Center (Bbrc)

Curated by ChEMBL
LigandPNGBDBM50543137(CHEMBL4634860)
Affinity DataIC50:  4nMAssay Description:Antagonist activity at TLR7 in mouse splenocytes assessed as inhibition of ssRNA40-induced IL6 productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Biocon Bristol Myers Squibb Research Center (Bbrc)

Curated by ChEMBL
LigandPNGBDBM50560351(CHEMBL4748638)
Affinity DataIC50:  38nMAssay Description:Antagonist activity at TLR7 in mouse splenocytes assessed as inhibition of ssRNA40-induced IL6 productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Biocon Bristol Myers Squibb Research Center (Bbrc)

Curated by ChEMBL
LigandPNGBDBM50543465(CHEMBL4636498)
Affinity DataIC50:  43nMAssay Description:Antagonist activity at TLR7 in mouse whole blood cells assessed as inhibition of gardiquimod induced IL-6 production by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Biocon Bristol Myers Squibb Research Center (Bbrc)

Curated by ChEMBL
LigandPNGBDBM50560355(CHEMBL4740968)
Affinity DataIC50:  55nMAssay Description:Antagonist activity at TLR7 in mouse splenocytes assessed as inhibition of ssRNA40-induced IL6 productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Biocon Bristol Myers Squibb Research Center (Bbrc)

Curated by ChEMBL
LigandPNGBDBM50560353(CHEMBL4792072)
Affinity DataIC50:  93nMAssay Description:Antagonist activity at TLR7 in mouse splenocytes assessed as inhibition of ssRNA40-induced IL6 productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Biocon Bristol Myers Squibb Research Center (Bbrc)

Curated by ChEMBL
LigandPNGBDBM50560356(CHEMBL4755173)
Affinity DataIC50:  97nMAssay Description:Antagonist activity at TLR7 in mouse splenocytes assessed as inhibition of ssRNA40-induced IL6 productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Biocon Bristol Myers Squibb Research Center (Bbrc)

Curated by ChEMBL
LigandPNGBDBM50560350(CHEMBL4783510)
Affinity DataIC50:  110nMAssay Description:Antagonist activity at TLR7 in mouse splenocytes assessed as inhibition of ssRNA40-induced IL6 productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Biocon Bristol Myers Squibb Research Center (Bbrc)

Curated by ChEMBL
LigandPNGBDBM50560348(CHEMBL4796453)
Affinity DataIC50:  120nMAssay Description:Antagonist activity at TLR7 in mouse splenocytes assessed as inhibition of ssRNA40-induced IL6 productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Biocon Bristol Myers Squibb Research Center (Bbrc)

Curated by ChEMBL
LigandPNGBDBM50560349(CHEMBL4782200)
Affinity DataIC50:  150nMAssay Description:Antagonist activity at TLR7 in mouse splenocytes assessed as inhibition of ssRNA40-induced IL6 productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Biocon Bristol Myers Squibb Research Center (Bbrc)

Curated by ChEMBL
LigandPNGBDBM50560346(CHEMBL4743698)
Affinity DataIC50:  170nMAssay Description:Antagonist activity at TLR7 in mouse P4H1 cells assessed as inhibition of imiquimod-induced IL6 productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Biocon Bristol Myers Squibb Research Center (Bbrc)

Curated by ChEMBL
LigandPNGBDBM50543142(CHEMBL4641633)
Affinity DataIC50:  180nMAssay Description:Antagonist activity at TLR7 in mouse whole blood assessed as inhibition of DOTAP-ssRNA40 induced IFNalpha production preincubated for 30 mins followe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Biocon Bristol Myers Squibb Research Center (Bbrc)

Curated by ChEMBL
LigandPNGBDBM50560347(CHEMBL4776103)
Affinity DataIC50:  220nMAssay Description:Antagonist activity at TLR7 in mouse splenocytes assessed as inhibition of ssRNA40-induced IL6 productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Biocon Bristol Myers Squibb Research Center (Bbrc)

Curated by ChEMBL
LigandPNGBDBM50560354(CHEMBL4740820)
Affinity DataIC50:  300nMAssay Description:Antagonist activity at TLR7 in mouse splenocytes assessed as inhibition of ssRNA40-induced IL6 productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Biocon Bristol Myers Squibb Research Center (Bbrc)

Curated by ChEMBL
LigandPNGBDBM50560352(CHEMBL4745239)
Affinity DataIC50:  1.20E+3nMAssay Description:Antagonist activity at TLR7 in mouse splenocytes assessed as inhibition of ssRNA40-induced IL6 productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetToll-like receptor 7(Mus musculus)
Biocon Bristol Myers Squibb Research Center (Bbrc)

Curated by ChEMBL
LigandPNGBDBM50560346(CHEMBL4743698)
Affinity DataIC50:  2.00E+3nMAssay Description:Antagonist activity at TLR7 in mouse splenocytes assessed as inhibition of ssRNA40-induced IL6 productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed