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Found 3 of ic50 for UniProtKB: P31938
TargetDual specificity mitogen-activated protein kinase kinase 1(Mus musculus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM104963(CHEMBL507361 | US11147816, PD0325901 | US11701360,...)
Affinity DataIC50:  0.330nMAssay Description:Inhibition of MEK1 in mouse colon 26 cells assessed as reduction in ERK1/2 phosphorylation after 1 hr by Western blot analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Mus musculus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50170831(CHEMBL188343 | N*6*-Cyclohexyl-N*2*-(4-morpholin-4...)
Affinity DataIC50:  8nMAssay Description:Inhibition of MEK1 in mouse C2C12 by ERK2 phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Mus musculus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50180839(CHEMBL1998165)
Affinity DataIC50:  20nMAssay Description:Inhibition of MEK1 in mouse C26 cells assessed as inhibition of ERK1/2 phosphorylation incubated for 1 hr by Western blottingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed