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Found 35 of ic50 for UniProtKB: P22985
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50320491(2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-METHYL-5-THIAZOLE...)
Affinity DataIC50:  4nMAssay Description:Inhibition of rat xanthine oxidaseMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50449104(CHEMBL3127117)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of rat xanthine oxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50333138(2-((4-methoxyphenoxy)methyl)-7-methyl-5H-[1,3,4]th...)
Affinity DataIC50:  289nMAssay Description:Inhibition of rat liver xanthine oxidase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50333141(7-methyl-2-(o-tolyloxymethyl)-5H-[1,3,4]thiadiazol...)
Affinity DataIC50:  362nMAssay Description:Inhibition of rat liver xanthine oxidase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50333140(2-((2-bromophenoxy)methyl)-7-methyl-5H-[1,3,4]thia...)
Affinity DataIC50:  413nMAssay Description:Inhibition of rat liver xanthine oxidase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50333139(2-((4-chlorophenoxy)methyl)-7-methyl-5H-[1,3,4]thi...)
Affinity DataIC50:  449nMAssay Description:Inhibition of rat liver xanthine oxidase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50333137(7-methyl-2-(phenoxymethyl)-5H-[1,3,4]thiadiazolo[3...)
Affinity DataIC50:  555nMAssay Description:Inhibition of rat liver xanthine oxidase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50333147(2-((2-fluorophenoxy)methyl)-7-methyl-5H-[1,3,4]thi...)
Affinity DataIC50:  590nMAssay Description:Inhibition of rat liver xanthine oxidase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50333143(2-((4-chloro-3-methylphenoxy)methyl)-7-methyl-5H-[...)
Affinity DataIC50:  623nMAssay Description:Inhibition of rat liver xanthine oxidase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM35440(ALLOPURINOL | MLS000069453 | SMR000059083 | cid_20...)
Affinity DataIC50:  753nMAssay Description:Inhibition of rat liver xanthine oxidase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50333133(7-methyl-2-(p-tolyloxymethyl)-5H-[1,3,4]thiadiazol...)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibition of rat liver xanthine oxidase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50333144(7-methyl-2-(m-tolyloxymethyl)-5H-[1,3,4]thiadiazol...)
Affinity DataIC50:  1.07E+3nMAssay Description:Inhibition of rat liver xanthine oxidase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50333146(2-((2,4-dimethylphenoxy)methyl)-7-methyl-5H-[1,3,4...)
Affinity DataIC50:  1.76E+3nMAssay Description:Inhibition of rat liver xanthine oxidase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50333142(2-((2-chlorophenoxy)methyl)-7-methyl-5H-[1,3,4]thi...)
Affinity DataIC50:  1.83E+3nMAssay Description:Inhibition of rat liver xanthine oxidase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50333136(2-((3-fluorophenoxy)methyl)-7-methyl-5H-[1,3,4]thi...)
Affinity DataIC50:  1.98E+3nMAssay Description:Inhibition of rat liver xanthine oxidase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50333145(7-methyl-2-((4-nitrophenoxy)methyl)-5H-[1,3,4]thia...)
Affinity DataIC50:  2.03E+3nMAssay Description:Inhibition of rat liver xanthine oxidase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50333135(2-((3-bromophenoxy)methyl)-7-methyl-5H-[1,3,4]thia...)
Affinity DataIC50:  2.56E+3nMAssay Description:Inhibition of rat liver xanthine oxidase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM35440(ALLOPURINOL | MLS000069453 | SMR000059083 | cid_20...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of Wistar albino rat xanthine oxidase isolated from liver using xanthine as substrate incubated for 15 mins prior to substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50333134(2-((3-chlorophenoxy)methyl)-7-methyl-5H-[1,3,4]thi...)
Affinity DataIC50:  6.18E+3nMAssay Description:Inhibition of rat liver xanthine oxidase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50423923(CHEMBL2313040)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of Wistar albino rat xanthine oxidase isolated from liver using xanthine as substrate incubated for 15 mins prior to substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50423922(CHEMBL2313041)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of Wistar albino rat xanthine oxidase isolated from liver using xanthine as substrate incubated for 15 mins prior to substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50423924(CHEMBL2313039)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of Wistar albino rat xanthine oxidase isolated from liver using xanthine as substrate incubated for 15 mins prior to substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50423932(CHEMBL2313031)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of Wistar albino rat xanthine oxidase isolated from liver using xanthine as substrate incubated for 15 mins prior to substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM35440(ALLOPURINOL | MLS000069453 | SMR000059083 | cid_20...)
Affinity DataIC50:  2.12E+4nMAssay Description:Inhibition of rat liver xanthine oxidase after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50423931(CHEMBL2313032)
Affinity DataIC50:  2.39E+4nMAssay Description:Inhibition of Wistar albino rat xanthine oxidase isolated from liver using xanthine as substrate incubated for 15 mins prior to substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50423933(CHEMBL2313030)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of Wistar albino rat xanthine oxidase isolated from liver using xanthine as substrate incubated for 15 mins prior to substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50423929(CHEMBL2313034)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of Wistar albino rat xanthine oxidase isolated from liver using xanthine as substrate incubated for 15 mins prior to substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50423928(CHEMBL2313035)
Affinity DataIC50:  3.42E+4nMAssay Description:Inhibition of Wistar albino rat xanthine oxidase isolated from liver using xanthine as substrate incubated for 15 mins prior to substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50423930(CHEMBL2313033)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibition of Wistar albino rat xanthine oxidase isolated from liver using xanthine as substrate incubated for 15 mins prior to substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50423926(CHEMBL2313037)
Affinity DataIC50:  4.66E+4nMAssay Description:Inhibition of Wistar albino rat xanthine oxidase isolated from liver using xanthine as substrate incubated for 15 mins prior to substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50423927(CHEMBL2313036)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Wistar albino rat xanthine oxidase isolated from liver using xanthine as substrate incubated for 15 mins prior to substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50423925(CHEMBL2313038)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Wistar albino rat xanthine oxidase isolated from liver using xanthine as substrate incubated for 15 mins prior to substrate addition by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50378419(CHEMBL570882)
Affinity DataIC50:  7.08E+4nMAssay Description:Inhibition of rat liver xanthine oxidase after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM60989((3S)-2-[(2S,3S)-2-(hydroxymethyl)-3-(3-methoxy-4-o...)
Affinity DataIC50:  8.03E+4nMAssay Description:Inhibition of rat liver xanthine oxidase after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50084979(3,5,7-Trihydroxy-2-[3-(4-hydroxy-3-methoxy-phenyl)...)
Affinity DataIC50:  8.03E+4nMAssay Description:Inhibition of rat liver xanthine oxidase after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed