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Found 4 of ic50 for UniProtKB: P20291
TargetArachidonate 5-lipoxygenase-activating protein(Rattus norvegicus)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052018(3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(qui...)
Affinity DataIC50:  10nMAssay Description:Inhibition of FLAP in rat whole blood assessed as inhibition of calcium ionophore A23187-induced LTB4 production preincubated for 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 5-lipoxygenase-activating protein(Rattus norvegicus)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359080(CHEMBL1922660)
Affinity DataIC50:  16nMAssay Description:Inhibition of FLAP in rat whole blood assessed as inhibition of calcium ionophore A23187-induced LTB4 production preincubated for 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 5-lipoxygenase-activating protein(Rattus norvegicus)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052018(3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(qui...)
Affinity DataIC50:  117nMAssay Description:Inhibition of FLAP in rat whole blood assessed as inhibition of calcium ionophore A23187-induced LTB4 production preincubated for 15 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 5-lipoxygenase-activating protein(Rattus norvegicus)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359080(CHEMBL1922660)
Affinity DataIC50:  239nMAssay Description:Inhibition of FLAP in rat whole blood assessed as inhibition of calcium ionophore A23187-induced LTB4 production preincubated for 15 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed