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Found 27 of ic50 for UniProtKB: P15539
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238115(CHEMBL4082403)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238115(CHEMBL4082403)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238114(CHEMBL4093575)
Affinity DataIC50:  21nMAssay Description:Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238115(CHEMBL4082403)
Affinity DataIC50: >100nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238103(CHEMBL4070323)
Affinity DataIC50:  102nMAssay Description:Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238104(CHEMBL4072871)
Affinity DataIC50:  170nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)
Affinity DataIC50:  190nMAssay Description:Inhibition of mouse CYP11B2 expressed in renal leiomyoblastoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50444549(CHEMBL3099695)
Affinity DataIC50:  210nMAssay Description:Inhibition of mouse CYP11B2 expressed in renal leiomyoblastoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238110(CHEMBL4088766)
Affinity DataIC50:  257nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238105(CHEMBL4099824)
Affinity DataIC50:  300nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238102(CHEMBL4065476)
Affinity DataIC50:  440nMAssay Description:Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50125049(CHEMBL3623830)
Affinity DataIC50:  530nMAssay Description:Inhibition of mouse CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238109(CHEMBL4091167)
Affinity DataIC50:  798nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238101(CHEMBL4104118)
Affinity DataIC50:  911nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238106(CHEMBL4072943)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238121(CHEMBL4077051)
Affinity DataIC50:  1.31E+3nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238108(CHEMBL4070230)
Affinity DataIC50:  1.34E+3nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238111(CHEMBL4060559)
Affinity DataIC50:  1.38E+3nMAssay Description:Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238119(CHEMBL4075207)
Affinity DataIC50:  1.47E+3nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238116(CHEMBL4079006)
Affinity DataIC50:  1.76E+3nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238117(CHEMBL4092081)
Affinity DataIC50:  1.89E+3nMAssay Description:Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50047262((R)-4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-y...)
Affinity DataIC50:  2.07E+3nMAssay Description:Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238123(CHEMBL4061565)
Affinity DataIC50:  2.74E+3nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238112(CHEMBL4101118)
Affinity DataIC50:  3.13E+3nMAssay Description:Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238113(CHEMBL4067686)
Affinity DataIC50:  5.10E+3nMAssay Description:Concentration required to inhibit the activity of Angiotensin I converting enzyme by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50238107(CHEMBL4064367)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse CYP11B2 expressed in HEK293 cells using deoxycorticosterone as substrate pretreated for 1 hr followed by substrate addition after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50125050(CHEMBL3623831)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed