Compile Data Set for Download or QSAR
maximum 50k data
Found 33 of ec50 for UniProtKB: P18090
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rattus norvegicus (Rat))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
Affinity DataEC50:  7nMAssay Description:Beta adrenergic receptor agonistic activity for the stimulation of accumulation of cyclic AMP in cultured C6 glioma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rattus norvegicus (Rat))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50007476(4-(3-tert-Butylamino-2-hydroxy-propoxy)-benzene-1,...)
Affinity DataEC50:  8.20nMAssay Description:Beta adrenergic receptor agonistic activity for the stimulation of accumulation of cyclic AMP in cultured C6 glioma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rattus norvegicus (Rat))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50007477(4-(3-tert-Butylamino-2-hydroxy-propoxy)-3-fluoro-b...)
Affinity DataEC50:  9.20nMAssay Description:Activity was evaluated by measuring the inhibition of isolated hog H+/K+ ATPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rattus norvegicus (Rat))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50019059((+/-)3-Fluoro-4-(1-hydroxy-2-methylamino-ethyl)-be...)
Affinity DataEC50:  40nMAssay Description:Stimulation of cyclic AMP accumulation in C6 glioma cells expressing adrenergic beta receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rattus norvegicus (Rat))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50019059((+/-)3-Fluoro-4-(1-hydroxy-2-methylamino-ethyl)-be...)
Affinity DataEC50:  40nMAssay Description:Agonistic potency at beta adrenergic receptor for the stimulation of accumulation of cyclic AMP in cultured C6 glioma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rattus norvegicus (Rat))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50029051((-)-arterenol | (-)-noradrenaline | (-)-norepineph...)
Affinity DataEC50:  52nMAssay Description:Stimulation of cyclic AMP accumulation in C6 glioma cells expressing adrenergic beta receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rattus norvegicus (Rat))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50019060((+/-)4-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-...)
Affinity DataEC50:  63nMAssay Description:Stimulation of cyclic AMP accumulation in C6 glioma cells expressing adrenergic beta receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rattus norvegicus (Rat))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
Affinity DataEC50:  230nMAssay Description:Agonistic potency at alpha-1 adrenergic receptor for the amine-induced increase of phosphatidylinositol breakdown in synaptoneurosomes from guinea pi...More data for this Ligand-Target Pair
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rattus norvegicus (Rat))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
Affinity DataEC50:  230nMAssay Description:Stimulation of cyclic AMP accumulation in C6 glioma cells expressing adrenergic beta receptorMore data for this Ligand-Target Pair
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337297(1-Adamantan-1-ylmethyl-3-(3-{2-[2-hydroxy-2-(8-hyd...)
Affinity DataEC50:  296nMAssay Description:Agonist activity at beta1 adrenoreceptor in rat left atria assessed as induction of ionotropic effectMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337292(1-(3-(2-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroq...)
Affinity DataEC50:  550nMAssay Description:Agonist activity at beta1 adrenoreceptor in rat left atria assessed as induction of ionotropic effectMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rattus norvegicus (Rat))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM35234(DL-[7-3H]norepinephrine | NOREPINEPHRINE | Noradre...)
Affinity DataEC50:  800nMAssay Description:Displacement of [3H]dihydroalprenolol from beta-adrenergic receptor in Sprague-Dawley rat cerebral cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337300(1-benzyl-3-(3-(2-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2...)
Affinity DataEC50:  900nMAssay Description:Agonist activity at beta1 adrenoreceptor in rat left atria assessed as induction of ionotropic effectMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rattus norvegicus (Rat))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50019057((+/-)4-Fluoro-5-(1-hydroxy-2-methylamino-ethyl)-be...)
Affinity DataEC50: >1.50E+3nMAssay Description:Agonistic potency at beta adrenergic receptor for the stimulation of accumulation of cyclic AMP in cultured C6 glioma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rattus norvegicus (Rat))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50019057((+/-)4-Fluoro-5-(1-hydroxy-2-methylamino-ethyl)-be...)
Affinity DataEC50: >1.50E+3nMAssay Description:Stimulation of cyclic AMP accumulation in C6 glioma cells expressing adrenergic beta receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337294(1-(2,6-dichlorobenzyl)-3-(3-(2-(2-hydroxy-2-(8-hyd...)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at beta1 adrenoreceptor in rat left atria assessed as induction of ionotropic effectMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rattus norvegicus (Rat))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50042998(5-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-d...)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at beta-adrenergic receptor in Sprague-Dawley rat cerebral cortex assessed as [3H]cAMP accumulation by liquid scintillation spectros...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rattus norvegicus (Rat))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50019060((+/-)4-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-...)
Affinity DataEC50:  2.00E+3nMAssay Description:Displacement of [3H]dihydroalprenolol from beta-adrenergic receptor in Sprague-Dawley rat cerebral cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50318159(8-Hydroxy-5-[(R)-1-hydroxy-2-(5,6-diethylindan-2-y...)
Affinity DataEC50:  2.31E+3nMAssay Description:Agonist activity at beta1 adrenoreceptor in rat left atria assessed as induction of ionotropic effectMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rattus norvegicus (Rat))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50042998(5-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-d...)
Affinity DataEC50:  4.00E+3nMAssay Description:Displacement of [3H]dihydroalprenolol from beta-adrenergic receptor in Sprague-Dawley rat cerebral cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rattus norvegicus (Rat))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50019060((+/-)4-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-...)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at beta-adrenergic receptor in Sprague-Dawley rat cerebral cortex assessed as [3H]cAMP accumulation by liquid scintillation spectros...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rattus norvegicus (Rat))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM35234(DL-[7-3H]norepinephrine | NOREPINEPHRINE | Noradre...)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at beta-adrenergic receptor in Sprague-Dawley rat cerebral cortex assessed as [3H]cAMP accumulation by liquid scintillation spectros...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337296(1-(biphenyl-2-yl)-3-(3-(2-(2-hydroxy-2-(8-hydroxy-...)
Affinity DataEC50:  5.77E+3nMAssay Description:Agonist activity at beta1 adrenoreceptor in rat left atria assessed as induction of ionotropic effectMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337293(1-(4-fluorobenzyl)-3-(3-(2-(2-hydroxy-2-(8-hydroxy...)
Affinity DataEC50:  6.30E+3nMAssay Description:Agonist activity at beta1 adrenoreceptor in rat left atria assessed as induction of ionotropic effectMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337295(1-benzhydryl-3-(3-(2-(2-hydroxy-2-(8-hydroxy-2-oxo...)
Affinity DataEC50:  8.89E+3nMAssay Description:Agonist activity at beta1 adrenoreceptor in rat left atria assessed as induction of ionotropic effectMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337291(1-(3-(2-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroq...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at beta1 adrenoreceptor in rat left atria assessed as induction of ionotropic effectMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rattus norvegicus (Rat))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50019061((+/-)4-(2-Amino-1-hydroxy-ethyl)-5-fluoro-benzene-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Stimulation of cyclic AMP accumulation in C6 glioma cells expressing adrenergic beta receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337298(1-(3-(2-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroq...)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at beta1 adrenoreceptor in rat left atria assessed as induction of ionotropic effectMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337301(1-(3-(2-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroq...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at beta1 adrenoreceptor in rat left atria assessed as induction of ionotropic effectMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50337299(1-(3-(2-(2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroq...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at beta1 adrenoreceptor in rat left atria assessed as induction of ionotropic effectMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rattus norvegicus (Rat))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50019061((+/-)4-(2-Amino-1-hydroxy-ethyl)-5-fluoro-benzene-...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at beta-adrenergic receptor in Sprague-Dawley rat cerebral cortex assessed as [3H]cAMP accumulation by liquid scintillation spectros...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rattus norvegicus (Rat))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50042997(4-(2-Amino-1-hydroxy-ethyl)-3,5-difluoro-benzene-1...)
Affinity DataEC50: >1.00E+5nMAssay Description:Stimulation of cyclic AMP accumulation in C6 glioma cells expressing adrenergic beta receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rattus norvegicus (Rat))
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50019061((+/-)4-(2-Amino-1-hydroxy-ethyl)-5-fluoro-benzene-...)
Affinity DataEC50: >1.00E+5nMAssay Description:Displacement of [3H]dihydroalprenolol from beta-adrenergic receptor in Sprague-Dawley rat cerebral cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed