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Found 41 of kd for UniProtKB: P40763
LigandPNGBDBM50605550(C-188-9 | Stat3 inhibitor c188-9 | Stat3 inhibitor...)
Affinity DataKd:  4.70nMAssay Description:Binding affinity to STAT3 (127 to 722 residues) (unknown origin) by microscale thermophoresis analysisMore data for this Ligand-Target Pair
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LigandPNGBDBM50588525(CHEMBL5177956)
Affinity DataKd:  21nMAssay Description:Binding affinity to human recombinant STAT3 expressed in Escherichia coli BL21 by MST assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50557878(CHEMBL4776801)
Affinity DataKd:  28nMAssay Description:Binding affinity to human recombinant STAT3 assessed as dissociation constant incubated for 15 mins by biolayer interferometryMore data for this Ligand-Target Pair
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LigandPNGBDBM50569086(CHEMBL4868479)
Affinity DataKd:  29nMAssay Description:Binding affinity to His-tagged STAT3-SH2 domain (127 to 722 residues) (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
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LigandPNGBDBM50602483(CHEMBL5175648)
Affinity DataKd:  34nMAssay Description:Binding affinity to recombinant GST tagged STAT3 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
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LigandPNGBDBM50514302(CHEMBL4452527)
Affinity DataKd:  44nMAssay Description:Binding affinity to His-SUMO-tagged human STAT3 (127 to 688 residues) expressed in Escherichia coli Rosette (DE3) assessed as dissociation constant u...More data for this Ligand-Target Pair
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LigandPNGBDBM50514302(CHEMBL4452527)
Affinity DataKd:  44nMAssay Description:Binding affinity to recombinant human His/SUMO-tagged STAT3 (127 to 688 residues) expressed in Escherichia coli Rosetta (DE3) incubated for 1 hr by f...More data for this Ligand-Target Pair
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LigandPNGBDBM50569071(CHEMBL4846365)
Affinity DataKd:  53nMAssay Description:Binding affinity to His-tagged STAT3-SH2 domain (127 to 722 residues) (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
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LigandPNGBDBM50569070(CHEMBL4864495)
Affinity DataKd:  63nMAssay Description:Binding affinity to His-tagged STAT3-SH2 domain (127 to 722 residues) (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
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LigandPNGBDBM50590873(CHEMBL5176684)
Affinity DataKd:  76nMAssay Description:Binding affinity to human STAT3 (127 to 722 residues) assessed as dissociation constant by MST assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50521054(CHEMBL4474417)
Affinity DataKd:  110nMAssay Description:Binding affinity to recombinant N-terminal His-tagged STAT3 (unknown origin) expressed in baculovirus infected Sf9 insect cells by SPR analysisMore data for this Ligand-Target Pair
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LigandPNGBDBM50590873(CHEMBL5176684)
Affinity DataKd:  114nMAssay Description:Binding affinity to human STAT3-SH2 domain (127 to 722 residues) assessed as dissociation constant by MST assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50605550(C-188-9 | Stat3 inhibitor c188-9 | Stat3 inhibitor...)
Affinity DataKd:  250nMAssay Description:Binding affinity to full length STAT3 (unknown origin) by Surface plasmon resonanceMore data for this Ligand-Target Pair
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LigandPNGBDBM50033887(CHEMBL3358611)
Affinity DataKd:  287nMAssay Description:Binding affinity to full-length His-tagged STAT3 (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50446146(CHEMBL3108909)
Affinity DataKd:  300nMAssay Description:Binding affinity to His-tagged STAT3 (unknown origin) by SPR spectroscopic analysisMore data for this Ligand-Target Pair
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LigandPNGBDBM50605546(CHEMBL5174100)
Affinity DataKd:  310nMAssay Description:Binding affinity to His-tagged STAT3 (127 to 722 residues) (unknown origin) incubated for 30 mins by MST assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50605547(CHEMBL5178793)
Affinity DataKd:  360nMAssay Description:Binding affinity to His-tagged STAT3 (127 to 722 residues) (unknown origin) incubated for 30 mins by MST assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50572604(CHEMBL4861762)
Affinity DataKd:  432nMAssay Description:Binding affinity to STAT3 (unknown origin) by SRB assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50605545(CHEMBL5182175)
Affinity DataKd:  460nMAssay Description:Binding affinity to His-tagged STAT3 (127 to 722 residues) (unknown origin) incubated for 30 mins by MST assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50353432(CHEMBL1829876 | US10196373, Compound 45O)
Affinity DataKd:  500nMAssay Description:Binding affinity to full length STAT3 (unknown origin) by Surface plasmon resonanceMore data for this Ligand-Target Pair
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LigandPNGBDBM50353432(CHEMBL1829876 | US10196373, Compound 45O)
Affinity DataKd:  504nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay at 50 uMMore data for this Ligand-Target Pair
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LigandPNGBDBM50353432(CHEMBL1829876 | US10196373, Compound 45O)
Affinity DataKd:  504nMAssay Description:Binding affinity to STAT3 (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50520522(CHEMBL4568628)
Affinity DataKd:  530nMAssay Description:Binding affinity to STAT3 in human SKOV3 cells assessed as equilibrium dissociation constant after 200 sec by SPR assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50605549(CHEMBL5175326)
Affinity DataKd:  590nMAssay Description:Binding affinity to His-tagged STAT3 (127 to 722 residues) (unknown origin) incubated for 30 mins by MST assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50605548(CHEMBL5204232)
Affinity DataKd:  640nMAssay Description:Binding affinity to His-tagged STAT3 (127 to 722 residues) (unknown origin) incubated for 30 mins by MST assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50556908(CHEMBL4777016 | US11299480, Example 134)
Affinity DataKd:  880nMAssay Description:Binding affinity to STAT3 (unknown origin) assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
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LigandPNGBDBM50605545(CHEMBL5182175)
Affinity DataKd:  960nMAssay Description:Binding affinity to His-tagged STAT3-SH2 domain (586 to 685 residues) (unknown origin) incubated for 30 mins by MST assayMore data for this Ligand-Target Pair
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LigandPNGBDBM549132(BDBM50556940 | US11299480, Example 138)
Affinity DataKd:  960nMAssay Description:Binding affinity to STAT3 (unknown origin) assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
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LigandPNGBDBM50396169(CHEMBL1337170)
Affinity DataKd:  1.53E+3nMAssay Description:Binding affinity to His-tagged STAT3-SH2 domain (127 to 722 residues) (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50446146(CHEMBL3108909)
Affinity DataKd:  1.57E+3nMAssay Description:Binding affinity to full length wild type STAT3-SH2 domain (unknown origin) assessed as equilibrium dissociation constant by SPR analysisMore data for this Ligand-Target Pair
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LigandPNGBDBM50528215(CHEMBL4562495)
Affinity DataKd:  3.22E+3nMAssay Description:Binding affinity to STAT3 CCD (unknown origin)More data for this Ligand-Target Pair
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LigandPNGBDBM50408830(CHEMBL5284089)
Affinity DataKd:  3.30E+3nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay at 50 uMMore data for this Ligand-Target Pair
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LigandPNGBDBM50408830(CHEMBL5284089)
Affinity DataKd:  4.10E+3nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay at 50 uMMore data for this Ligand-Target Pair
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LigandPNGBDBM50353432(CHEMBL1829876 | US10196373, Compound 45O)
Affinity DataKd:  4.57E+3nMAssay Description:Binding affinity to His-tagged STAT3 (127 to 722 residues) (unknown origin) incubated for 30 mins by MST assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50558620(CHEMBL4789066)
Affinity DataKd:  4.59E+3nMAssay Description:Binding affinity to STAT3 (unknown origin) expressed in Escherichia coli by CM5 sensor chip immobilization based SPR assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50607004(CHEMBL5220221)
Affinity DataKd:  5.02E+3nMAssay Description:Binding affinity to full length wild type STAT3-SH2 domain (unknown origin) assessed as equilibrium dissociation constant by SPR analysisMore data for this Ligand-Target Pair
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LigandPNGBDBM50408831(CHEMBL5271534)
Affinity DataKd:  6.60E+3nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay at 50 uMMore data for this Ligand-Target Pair
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LigandPNGBDBM50200777(CHEMBL3985200)
Affinity DataKd:  7.93E+3nMAssay Description:Binding affinity to STAT3 (unknown origin) expressed in Escherichia coli expression system by SPR assayMore data for this Ligand-Target Pair
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LigandPNGBDBM50408827(CHEMBL5282950)
Affinity DataKd:  1.55E+4nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay at 50 uMMore data for this Ligand-Target Pair
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LigandPNGBDBM50408826(CHEMBL5268863)
Affinity DataKd:  4.50E+4nMAssay Description:Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay at 50 uMMore data for this Ligand-Target Pair
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LigandPNGBDBM50593518(CHEBI:80908 | TELOCINOBUFAGIN | telocinobufagin)
Affinity DataKd:  5.03E+4nMAssay Description:Binding affinity to STAT3 (unknown origin) assessed as dissociation constant (KD) by surface plasmon resonance assayMore data for this Ligand-Target Pair
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